A5028590088- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Tuberculosis Research and Epidemiology
- Long-Term Effects of COVID-19
- Infectious Diseases and Tuberculosis
- Chronic Lymphocytic Leukemia Research
- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Streptococcal Infections and Treatments
- Animal Virus Infections Studies
- Bacterial Infections and Vaccines
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Diagnosis and treatment of tuberculosis
- Bacterial Identification and Susceptibility Testing
- Rabies epidemiology and control
- Infections and bacterial resistance
- COVID-19 Impact on Reproduction
- Fungal Infections and Studies
- Vaccine Coverage and Hesitancy
- HIV Research and Treatment
- Celiac Disease Research and Management
- Research on Leishmaniasis Studies
Azienda Ospedaliera Pugliese Ciaccio
2012-2025
University of Bonn
2022
The University of Texas MD Anderson Cancer Center
2022
UCLouvain
2022
Université Laval
2022
Institute for Biomedical and Pharmaceutical Research
2022
Becton Dickinson (United States)
2012
Mylan (Switzerland)
2012
Società Italiana di Medicina Generale
2012
BioAge (Italy)
2006
The DNA methylation levels of host cell genes increase with the severity cervical intraepithelial neoplasia (CIN) grade and are very high in cancer. Our study aims to evaluate FAM19A4 hsa-miR124-2 Atypical Squamous cells high-grade squamous lesions (ASC-H) CIN1, defined as low-grade (LSILs) by Bethesda classification, possible early warning biomarkers for managing women high-risk HPV infections (hrHPV). tests were conducted on fifty-six screening samples from a subset aged 30–64 years old....
Vitamin D might play a role in counteracting COVID-19, albeit strong evidence is still lacking the literature. The present multicenter real-practice study aimed to evaluate differences of 25(OH)D3 serum levels adults tested for SARS-CoV-2 (acute COVID-19 patients, subjects healed from and non-infected ones) recruited over 6-month period (March–September 2021). In sample 117 subjects, statistically significant difference was found, with acute patients demonstrating lowest (9.63 ± 8.70 ng/mL),...
The continuous emergence of SARS-CoV-2 variants and subvariants poses significant public health challenges. latest designated subvariant JN.1, with all its descendants, shows more than 30 mutations in the spike gene. JN.1 has raised concerns due to genomic diversity potential enhance transmissibility immune evasion. This study aims analyse molecular characteristics JN.1-related lineages (JN.1*) identified Italy from October 2023 April 2024 evaluate neutralization activity against a subsample...
Antibody response following SARS-CoV2 vaccination is somewhat defective in chronic lymphocytic leukemia (CLL). Moreover, the correlation between serologic and status of cellular immunity has been poorly studied.This study was undertaken to assess humoral immune responses BNT162b2 messenger RNA (mRNA) COVID-19 CLL.The presence spike antibodies assessed at a median time 14 days from second vaccine dose 70 CLL followed-up single institution.The antibody rate (RR) patients 58.5%, compared 100%...
The rapid emergence and worldwide detection of the SARS-CoV-2 Omicron variant underscore importance robust genomic surveillance systems prompt information sharing among global public health partners. has rapidly replaced Delta as a dominating because natural selection, favoring with higher infectivity stronger vaccine breakthrough capability. is also known B.1.1.529. It four sub-variants, indicated BA.1, BA.2, BA.3 BA.4. Among them, BA.1 currently prevailing sub-variant, BA.2 been found to...
Although analysis of the Human papillomavirus (HPV) genotype spread in a particular area has crucial impact on public health and prevention programmes, there is lack epidemiological data regarding HPV Calabria region Italy. We therefore update information age/genotype distribution by retrospectively analysing cohort women, with without cervical lesions, living Calabria, who underwent DNA testing; moreover, we also evaluated subset patients lesions. Cervical scrape specimens obtained from...
The new Coronavirus identified in Whuan at the end of 2019 (SARS-CoV-2) belongs to Beta genus and is responsible for pandemia (COVID-19). Infected children may be asymptomatic or present fever, dry cough, fatigue gastrointestinal symptoms. CDC recommends that clinicians should decide test patients based on presence signs symptoms compatible with COVID-19.42 (the majority < 5 years age) were referred, our Pediatric Department, as possible cases COVID-19 infection. Blood analysis, chest X-ray,...
In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of disease 2019 (COVID-19), emerged in Wuhan, China. Several variants concern (VOCs) have been identified so far. Recently, B.1.1.529 (Omicron) variant SARS-CoV-2 spread rapidly worldwide. We describe first case Omicron genetic lineage BA.1 our region. The patient is a physician who traveled to Johannesburg (South Africa) and returned Reggio Calabria (Italy). He underwent screening before...
The clinical presentation of COVID-19 is non-specific, and to improve limit the spread SARS-CoV-2 virus, an accurate diagnosis with a robust method needed. A total 500 nasopharyngeal swab specimens were tested for SARS-CoV-2. Of these, 184 samples found be positive Allplex™ 2019-nCoV Assay, which fully automated. All retested TaqPath™ CE-IVD RT-PCR Kit (after this, referred as COVID-19), semi-automated. comparison RT-qPCR genes target points shows only one point in common, N gene. Therefore,...
Nursing home (NH) residents suffered the greatest impact of COVID-19 pandemic. Limited data are available on vaccine-induced immunity and protection ensured by a prior infection in this population. The present study aims to monitor antibody levels their persistence over 6-month period NH according history SARS-CoV-2 infection. We measured anti-trimeric Spike IgG sample 395 from 25 NHs 6 Italian Regions at enrolment (prior first dose vaccine, T0) then after 2 (T1) months (T2) following...
Diagnostic laboratory tools are essential to keep everyone safe and track newly emerging variants; on the other hand, "filter" screening tests recognizing positivity valuable avoid hectic work that, besides COVID-19, also part of routine. Therefore, complementary assays, such as rapid antigen (RATs), in controlling monitoring virus spread within community, especially asymptomatic population. A subset nasopharyngeal swab specimens resulted SARS-CoV-2 positive investigated for genomic...
The rapid emergence and worldwide detection of the SARS-CoV-2 omicron variant underscore importance robust genomic surveillance systems prompt information sharing among global public health partners. Omicron has rapidly replaced delta as a dominating because natural selection, favoring with higher infectivity more strong vaccine breakthrough ability. Also known B.1.1.529, four sub-variants, BA.1, BA.2, BA.3, BA.4. Among them, BA.1 is currently prevailing sub-variant, BA.2 found to be able...
A Cryptococcus subspecies, neoformans, represents the most pathogenic infection for humans, particularly in immunocompromised hosts (e.g., cancer patients, drug users). In present study, we described a 67-year old woman with non-Hodgkin lymphoma who developed an infectious disease sustained by neoformans. Biochemical data documented decrease lymphocytes count while clinical evaluation was suggestive on meningeal infection. The microbiological analysis of serum, using dilution pattern through...
Tuberculous meningitis (TBM) is a severe form of tuberculosis. We report the development fatal TBM in 2-year-old previously healthy child, suggesting that must be evaluated children all ages with non-specific symptoms central nervous involvement because diagnostic delay induces negative prognosis.
The rapid emergence and worldwide detection of the SARS-CoV-2 omicron variant underscore importance robust genomic surveillance systems prompt information sharing among global public health partners. Omicron has rapidly replaced delta as a dominating because natural selection, favoring with higher infectivity more strong vaccine breakthrough ability. three lineages or sub-variants, BA.1 (B.1.1.529.1), BA.2 (B.1.1.529.2), BA.3 (B.1.1.529.3). Among them, is currently prevailing sub-variant....