A5010330527- Orthodontics and Dentofacial Orthopedics
- dental development and anomalies
- Dental Radiography and Imaging
- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- Cleft Lip and Palate Research
- Dental Trauma and Treatments
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Dental materials and restorations
- Craniofacial Disorders and Treatments
- Oral and Maxillofacial Pathology
- Assisted Reproductive Technology and Twin Pregnancy
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Medical and Biological Sciences
- Ovarian cancer diagnosis and treatment
- SARS-CoV-2 and COVID-19 Research
- Ectopic Pregnancy Diagnosis and Management
- Liver Disease Diagnosis and Treatment
- Prenatal Screening and Diagnostics
- Congenital Heart Disease Studies
- Research on Leishmaniasis Studies
- Oral and Craniofacial Lesions
Sapienza University of Rome
1991-2025
Magna Graecia University
2016-2025
University of Rome Tor Vergata
2013-2024
Policlinico Umberto I
2019-2024
Department of Medical Sciences
2020-2024
Azienda Ospedaliero Universitario Mater Domini
2020-2022
Fatebenefratelli Hospital
2004-2015
Azienda Ospedaliera Fatebenefratelli e Oftalmico
2002-2011
Ospedale San Pietro Fatebenefratelli
2001
University of Reggio Calabria
1994-1998
Abstract Since December 2019, coronavirus disease 2019 (COVID-19) pandemic has spread from China all over the world and many COVID-19 outbreaks have been reported in long-term care facilities (LCTF). However, data on clinical characteristics prognostic factors such settings are scarce. We conducted a retrospective, observational cohort study to assess baseline predictors of mortality patients hospitalized after an outbreak SARS-CoV-2 infection LTCF. A total 50 were included. Mean age was 80...
Abstract Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) persistence in COVID‐19 patients could play a key role the emergence of variants concern. The rapid intra ‐host evolution SARS‐CoV‐2 may result an increased transmissibility, immune and therapeutic escape which be direct consequence epidemic currents. In this context, longitudinal retrospective study on eight consecutive with persistent infection, from January 2022 to March 2023, was conducted. To characterize ‐ inter...
ABSTRACT TBCK (TBC1 Domain‐Containing Kinase) encodes a protein playing role in actin organization and cell growth/proliferation via the mTOR signaling pathway. Deleterious biallelic variants cause Hypotonia, infantile, with psychomotor retardation characteristic facies 3. We report on three affected sibs, also displaying cardiac malformations. The parents, consanguineous couple of first cousins, were referred to schedule invasive diagnosis for their sixth pregnancy. They known carry...
Abstract Objectives To assess the efficacy of remote blood pressure monitoring to prevent readmission due complications hypertensive disorders pregnancy. Methods The search was conducted using MEDLINE, EMBASE, Web-of-Sciences, Scopus, ClinicalTrial.gov , OVID and Cochrane-Library as electronic databases from inception each database November 2023. Selection criteria included randomized controlled trials postpartum individuals or telehealth strategies vs. routine-care. primary outcome...
Cholangiocarcinoma (CCA) is a very aggressive cancer showing the presence of high stem cells (CSCs). Doublecortin-like kinase1 (DCLK1) has been demonstrated as CSC marker in different gastroenterological solid tumors. Our aim was to evaluate vitro expression and biological function DCLK1 intrahepatic CCA (iCCA) perihilar (pCCA).Specimens surgically resected human were enzymatically digested, submitted immunosorting for specific markers (LGR5 [leucine-rich repeat-containing G protein-coupled...
Adnexal masses are not common in pregnancy. They often discovered incidentally during routine ultrasound examinations. In general, 24%–40% of the cases benign tumors; up to 8% malignant tumors. usually asymptomatic, but sometimes can be responsible for abdominal or pelvic pain. Transvaginal and transabdominal is essential define morphology distinguish between cases. Magnetic resonance imaging a complementary examination when findings equivocal useful additional better tissue planes relations...
The aims of this investigation were to cephalometrically study the short-term skeletal and dental modifications induced by rapid palatal expansion in a sample 20 patients (10 male, 10 female), aged 6–10 years (mean age 8 years) mixed dentition with uni- or bilateral posterior crossbite, mild Class II malocclusion, an increased vertical dimension (FMA, SN^GoGn), compare them untreated matched control group subjects male mean years.Cephalometric analysis showed that maxilla displayed tendency...
Abstract Introduction The pathophysiology of sepsis consists two phases. A first phase characterized by a substantial increase pro-inflammatory mediators including cytokines and systemic inflammatory markers, second (immunoparalysis, immunodysregulation) associated with the rise anti-inflammatory mediators. In this study we prospectively analyzed 52 consecutive patients diagnosis response syndrome (SIRS) at hospital admission to evaluate prognostic early diagnostic performance interleukin-10...
Abstract Background Bond strength of orthodontic composite is strongly influenced by molecular and structural mechanisms. Aim this in vitro study was to compare bond light-cure composites measuring debonding forces evaluating locations failure. Investigations on chemical compositions clarified adhesive behaviors abilities, exploring effects ageing processes junction materials. Methods Twelve enamel discs, from human premolars, were randomly coupled one system (Transbond XT™ 3 M UNITEK, USA,...
Recent studies have shown that the age-specific seroprevalence of H pylori infection parallels hepatitis A (HAV), suggesting similar modes transmission. The aim this study was to investigate seroepidemiology and HAV in same setting.A sample 705 resident subjects (273 men, age range 1-87 years, median 50) who attended outpatient medical centre rural town Cirò, Southern Italy (11,000 inhabitants) for blood testing were recruited.All completed a structured questionnaire. serum drawn from each...
Procalcitonin (PCT) is a polypeptide with several cationic aminoacids in its chemical structure and it well known marker of sepsis. It now emerging that PCT might exhibit some anti-inflammatory effects. The present study, based on the evaluation vitro interaction between bacterial lipopolisaccharide (LPS), reports new data supporting interesting potentially useful activity PCT.PCT significantly decreased (p < 0.05) limulus amoebocyte lysate (LAL) assay reactivity LPS from both Salmonella...
In open bite case treatments, a proper diagnostic differentiation is essential in determining the appropriate corrective procedures. Dental bites are generally more responsive to treatment with orthodontics alone, whereas skeletal often require combination of and orthognathic surgery. Patient selection principles for non-surgical routinely include fixed appliances both labial or lingual. However, removable clear aligners have gained consistent popularity complex cases including...
Abstract Introduction Association between persistency of a patent ductus arteriosus (PDA) and morbidity in preterm newborns is still controversial. We aimed to investigate the relation PDA large retrospective study. Methods A case-control study including neonates consecutively admitted Neonatal Intensive Care Unit (NICU), with gestational age (GA) < 32 weeks or body birth weight (BW) 1500 g, over 5-year period. Newborns were divided into Cases Controls, according presence absence...
The activity of the SARS-CoV-2 virus has not yet been studied in a post-mortem setting. absence these data led to prohibition exposure infected corpses during burial procedures. Our aim was assess virus’s persistence and possibility transmission phase including autopsy staff. sample group included 29 patients who were admitted our Covid-19 Centre died hospitalisation All swabs subjected one-step real-time reverse transcription polymerase chain reaction with cycle threshold (Ct) values. Swab...