A5070572496- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Gynecological conditions and treatments
- Pelvic floor disorders treatments
- Intraperitoneal and Appendiceal Malignancies
- Colorectal and Anal Carcinomas
- Estrogen and related hormone effects
- Immunotherapy and Immune Responses
- PARP inhibition in cancer therapy
- Reproductive Biology and Fertility
- Anorectal Disease Treatments and Outcomes
- Cancer Immunotherapy and Biomarkers
- Urinary Bladder and Prostate Research
- Glycosylation and Glycoproteins Research
- BRCA gene mutations in cancer
- Cancer Risks and Factors
- Lymphoma Diagnosis and Treatment
- Intestinal and Peritoneal Adhesions
- Hernia repair and management
- Immune Cell Function and Interaction
- Menopause: Health Impacts and Treatments
- Cancer Mechanisms and Therapy
Policlinico Umberto I
2015-2024
Sapienza University of Rome
2015-2024
Policlinico S.Orsola-Malpighi
2022
Universidad Cardenal Herrera CEU
2022
Dillinger Hütte (Germany)
2022
University of Pisa
1994-2020
Università Campus Bio-Medico
2000-2019
Azienda Ospedaliera Universitaria Pisana
2019
European Institute of Oncology
2006-2015
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2015
Pelvic lymph nodes are the most common site of extrauterine tumor spread in early-stage endometrial cancer, but clinical impact lymphadenectomy has not been addressed randomized studies. We conducted a trial to determine whether addition pelvic systematic standard hysterectomy with bilateral salpingo-oophorectomy improves overall and disease-free survival. From October 1, 1996, through March 31, 2006, 514 eligible patients preoperative International Federation Gynecology Obstetrics stage I...
The objective of this work is to assess the 5-year outcomes patients undergoing conization for high-grade cervical lesions that simultaneously present as risk factors in persistence HPV infection and positivity surgical resection margins. This a retrospective study evaluating lesions. All included had both positive margins experienced at 6 months. Associations were evaluated with Cox proportional hazard regression summarized using ratio (HR). charts 2966 reviewed. Among whole population, 163...
PURPOSE: Neoadjuvant chemotherapy (NACT) and radical surgery (RS) have emerged as a possible alternative to conventional radiation therapy (RT) in locally advanced cervical carcinoma. In 1990, phase III trial was undertaken verify such hypothesis terms of survival treatment-related morbidity. PATIENTS AND METHODS: Patients with squamous cell, International Federation Gynecology Obstetrics stage IB2 cancer were eligible for the study. They received cisplatin-based NACT followed by RS (type V...
No randomised trials have addressed the value of systematic aortic and pelvic lymphadenectomy (SL) in ovarian cancer macroscopically confined to pelvis. This study was conducted investigate role SL compared with lymph nodes sampling (CONTROL) management early stage cancer. A total 268 eligible patients intrapelvic carcinoma were (N=138) or CONTROL (N=130). The primary objective compare proportion retroperitoneal nodal involvement between two groups. Median operating time longer more required...
Neoadjuvant chemotherapy (NACT) and radical surgery (RS) have emerged as a possible alternative to conventional radiation therapy (RT) in locally advanced cervical carcinoma. In 1990, phase III trial was undertaken verify such hypothesis terms of survival treatment-related morbidity.Patients with squamous cell, International Federation Gynecology Obstetrics stage IB2 cancer were eligible for the study. They received cisplatin-based NACT followed by RS (type V hysterectomy plus systematic...
The high recurrence rate and the low overall survival in ovarian cancer suggest that a more specific therapeutic approach addition to conventional treatment is required. Translational clinical research investigating new molecular targets order find an alternative way affect tumor growth minimize overlap of toxicity antiblastic agents. Given its implication many cellular activities including regulation cell growth, motility, survival, proliferation, protein synthesis, autophagy,...