A5047365004- Ovarian cancer diagnosis and treatment
- Lung Cancer Treatments and Mutations
- Advanced Breast Cancer Therapies
- Economic and Financial Impacts of Cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Brain Metastases and Treatment
- HER2/EGFR in Cancer Research
- Meta-analysis and systematic reviews
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Health Systems, Economic Evaluations, Quality of Life
- BRCA gene mutations in cancer
- Colorectal and Anal Carcinomas
- Cancer Treatment and Pharmacology
- Renal cell carcinoma treatment
- Artificial Intelligence in Healthcare and Education
- Metastasis and carcinoma case studies
- Endometrial and Cervical Cancer Treatments
- Medication Adherence and Compliance
- Advances in Oncology and Radiotherapy
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Male Breast Health Studies
- Protease and Inhibitor Mechanisms
- Reproductive Biology and Fertility
- Lung Cancer Research Studies
- Head and Neck Cancer Studies
Ospedali Riuniti Umberto I
2023-2025
Università degli Studi di Enna Kore
2024-2025
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2023
Ospedale Garibaldi
2012-2021
Ospedale per gli Infermi
2015
Presidio Ospedaliero
2015
University of Turin
1996-1997
University of Catania
1993
Purpose: Adrenocortical cancer (ACC) is an aggressive tumor characterised by a high recurrence rate and poor response to treatment. This study analyses consecutive series of ACC patients evaluate the prognostic value various clinical pathological characteristics. Methods: We retrospectively evaluated 32 followed at our Medical Center from 1997 2015 age diagnosis, gender, functional status, stage type treatment with respect overall survival (OS) disease-free (DFS) as determined Kaplan–Meier...
In recent years, generative Artificial Intelligence models, such as ChatGPT, have increasingly been utilized in healthcare. Despite acknowledging the high potential of AI models terms quick access to sources and formulating responses a clinical question, results obtained using these still require validation through comparison with established guidelines. This study compares model eight questions Italian Association Medical Oncology (AIOM) guidelines for ovarian cancer.
Background: Adherence to oral anticancer therapies among breast cancer patients is an often-overlooked issue. Lack of patients’ compliance can be caused by several factors, and may hinder the efficacy prescribed medication, determining shorter than expected survival. In this context, few data are available about adherence CDK4/6 inhibitors in real-world practice. We report here results a retrospective analysis abemaciclib plus endocrine therapy cohort women with hormone receptor-positive...
Background: Adherence to oral anticancer therapies among breast cancer patients is an often-overlooked issue. A lack of patient compliance can be caused by several factors, and may hinder the efficacy prescribed medication, leading a shorter than expected survival. In this context, few data about adherence CDK4/6 inhibitors in real-world practice are available. We report here results retrospective analysis abemaciclib plus endocrine therapy cohort women with hormone receptor-positive (HR+),...
Background/Aim: A high percentage of cancer patients use complementary therapies (CM) during their disease journey. Several barriers for CM prescription still exist among oncologists. This study explored oncologists' attitudes toward prescribing with oral supplements or confirming prescriptions made by others. Materials and Methods: The employed a mixed semi-quantitative qualitative research strategy via web-based platform interview as preliminary step program observational studies on the...
Background: Mixed neuroendocrine–non-neuroendocrine tumors (MINEN) of the liver are exceptionally rare, with limited data available regarding their clinical behavior, pathogenesis, and optimal management. The coexistence hepatocellular carcinoma (HCC) neuroendocrine (NEC) within presents diagnostic therapeutic challenges. Methods: A systematic literature search was conducted on PubMed, identifying cases primary mixed HCC NEC in liver. adhered to PRISMA guidelines, relevant studies were...
Patients with luminal breast cancer (BC) may develop central nervous system metastases in 20%-40% of cases. Radiation or surgical therapy represents the cornerstone treating metastases. Meanwhile, best practice for metastatic BC involves using cyclin-dependent kinase 4/6 inhibitors combined endocrine therapy. To our knowledge, this is first case to report a dramatic response abemaciclib plus without radiation therapy, particularly patient who presented seizures and sudden coma. She received...
Abstract: A case of primary liver cancer showing combined hepatocellular and cholangiocellular features an associated pseudosarcomatous (schwannomatous) component is presented. Histologically, compact microtrabecular glandular patterns in a dense fibrous stroma were recognized. The latter showed transition towards spindle cell sarcomatous growth several areas both the lymph‐node metastasis. Glandular expressed acidic mucins AE1‐reactive keratins; albumin mRNA was detected by situ...
Chronic inflammation and cytokine storm can cause uncontrolled events in cancer. Pro-inflammatory molecules released by malignant cells send signals to the brain, liver, neuroendocrine cells, interfering with appetite promoting anorexia. Malnutrition cancer patients is associated increased treatment toxicity, reduced physical efficiency, decreased survival. Therefore, early recognition of malnutrition could improve quality life, compliance, The aim study was explore relationship between...
5503^ Background: few drugs are available for patients (pts) with platinum resistant or refractory AOC; their efficacy is scanty. Evidence on antiangiogenic in AOC increasing. Pazopanib an oral multi-kinase inhibitor of VEGFR-1, -2, -3, PDGFR-α and -β c-Kit properties. Methods: pts disease progressing during within 6 months from the last platinum-based chemotherapy, aged≤75, ECOG PS 0-1 were eligible a multicenter comparative randomized phase 2 trial weekly paclitaxel (wP, 80 mg/m² dd 1, 8,...
COVID-19 is a global public health emergency. The increasing spread of presents challenges for the clinical care patients with gynecological tumors. Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) performed survey to evaluate impact pandemic on medical treatment cancer, focus chemotherapy oral poly(ADP)-ribose polymerase inhibitors (PARP-i).The consisted self-administered online questionnaire, sent via email between November 2020 January 2021 all members MITO...
Introduction: In recent years, generative Artificial Intelligence models, such as ChatGPT, have been increasingly utilized in healthcare. Despite acknowledging the high potential of AI models terms quick access to sources and formulating a response clinical question, results obtained using these still require validation through comparison with established guidelines. This study compares responses model eight questions Italian Association Medical Oncology (AIOM) guidelines for ovarian cancer....