A5058295876- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Nutrition and Health in Aging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metabolism, Diabetes, and Cancer
- Pancreatic and Hepatic Oncology Research
- Cancer-related molecular mechanisms research
- FOXO transcription factor regulation
- Gallbladder and Bile Duct Disorders
- Drug-Induced Hepatotoxicity and Protection
- Biliary and Gastrointestinal Fistulas
- Cancer Cells and Metastasis
- Clinical Nutrition and Gastroenterology
- Infectious Encephalopathies and Encephalitis
- Hepatitis Viruses Studies and Epidemiology
- Electrolyte and hormonal disorders
- Neurological and metabolic disorders
- Child Nutrition and Feeding Issues
- Cancer Diagnosis and Treatment
- Digestive system and related health
- Epilepsy research and treatment
- Hepatitis C virus research
Sapienza University of Rome
2017-2025
Creative Research Enterprises (United States)
2019
Abstract Background Sarcopenia and myosteatosis have been associated to a poor prognosis of cirrhosis higher incidence hepatic encephalopathy (HE). The prognostic implications visceral subcutaneous adiposity are less known. Aim To evaluate the modifications adipose tissue after TIPS investigate their relationships with modification muscle mass post‐TIPS HE. Patients Methods 35 cirrhotic patients submitted were retrospectively studied. skeletal index (SMI), attenuation (myosteatosis), (SATI),...
Cholangiocarcinoma (CCA) is a very aggressive cancer showing the presence of high stem cells (CSCs). Doublecortin-like kinase1 (DCLK1) has been demonstrated as CSC marker in different gastroenterological solid tumors. Our aim was to evaluate vitro expression and biological function DCLK1 intrahepatic CCA (iCCA) perihilar (pCCA).Specimens surgically resected human were enzymatically digested, submitted immunosorting for specific markers (LGR5 [leucine-rich repeat-containing G protein-coupled...
Abstract Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive cancer with marked resistance to chemotherapeutics without therapies. The tumour microenvironment of iCCA enriched Cancer-Stem-Cells expressing Epithelial-to-Mesenchymal Transition (EMT) traits, being these features associated aggressiveness and drug resistance. Treatment the anti-diabetic Metformin, has been recently reduced incidence iCCA. We aimed evaluate anti-cancerogenic effects Metformin in vitro vivo on primary...
Hepatic encephalopathy (HE) is a common complication of advanced liver disease and acute failure. It condition that features several neuropsychiatric symptoms affect mortality, morbidity the quality patients’ caregivers’ lives. An HE diagnosis generally an exclusion diagnosis. Once patient admitted to hospital, clinical examination, blood tests eventually neuroimaging should be performed with aim ruling out other causes brain dysfunction. Moreover, recognized using various precipitants can...
Hepatic Encephalopaty (HE) is a common complications of advanced liver disease and acute failure. It condition that features both neurological psychiatric symptoms, affects mortality, morbidity quality patients caregivers’ life. HE diagnosis generally an exclusion diagnosis. Once the patient admitted to hospital, clinical examination, blood tests eventually neuroimaging should be performed in order rule out other causes brain dysfunction. Moreover, recognizes various precipitants can...