A5016829240- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Nutrition and Health in Aging
- Gastroesophageal reflux and treatments
- Hepatitis Viruses Studies and Epidemiology
- Colorectal Cancer Screening and Detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal disorders and treatments
- Hepatitis C virus research
- Inflammatory Bowel Disease
- Liver physiology and pathology
- Liver Diseases and Immunity
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Microscopic Colitis
- Eosinophilic Esophagitis
- Spondyloarthritis Studies and Treatments
- COVID-19 Clinical Research Studies
- Gastrointestinal Tumor Research and Treatment
- Epilepsy research and treatment
- Vitamin D Research Studies
- Long-Term Effects of COVID-19
- Pancreatic and Hepatic Oncology Research
Sapienza University of Rome
2016-2025
University of Padua
2025
Ospedale Santa Maria Goretti
2014-2024
Società Italiana di Reumatologia
2019
NIHR Clinical Research Network
2019
Lymphatic Education & Research Network
2019
Creative Research Enterprises (United States)
2019
University of Rome Tor Vergata
2019
Policlinico Umberto I
2018
St. Marien Hospital
2018
Hepatorenal syndrome (HRS), a serious complication of cirrhosis, is associated with high mortality without treatment. Terlipressin albumin effective in the reversal HRS. Where terlipressin not available, as United States, midodrine and octreotide are used an alternative treatment The aim was to compare effectiveness plus versus HRS randomized controlled trial. Twenty‐seven patients were receive (TERLI group) 22 (MID/OCT group). TERLI group received by intravenous infusion, initially 3 mg/24...
<b>Background:</b> Cold polypectomy techniques (without electrocautery) by means of biopsy forceps or snare are widely adopted for the removal subcentimetric polyps. However, few data available on safety this approach. The aim study was to assess cold polyps, as well rate advanced neoplasia in these lesions. <b>Patients and methods:</b> In a prospective multicenter trial, consecutive patients with at least one < 10-mm polyp colonoscopy were prospectively included. All polyps detected within...
Abstract Large spontaneous portal-systemic shunts have been occasionally described in patients with cirrhosis. This study was undertaken to assess the prevalence of cirrhosis recurrent or persistent hepatic encephalopathy (HE) as compared without HE. Fourteen HE (cases) and 14 previous present signs overt matching for age degree liver failure (controls) were studied. Each patient underwent neurological assessment cerebral magnetic resonance (MR) imaging exclude organic pathological...
Screening for hepatic encephalopathy (HE) that does not cause obvious disorientation or asterixis (minimal HE [MHE]/grade 1 HE) is important. We examined if the animal naming test (ANT1 ) (maximum number of animals listed in minute) useful this context. In total, 208 healthy controls, 40 controls with inflammatory bowel disease, and 327 consecutive patients cirrhosis underwent ANT1 . Patients were tested MHE by psychometric score, 146 assessed electroencephalography; 202 followed up...
Muscle alterations (myosteatosis and sarcopenia) are frequent in cirrhosis related to some complications including overt hepatic encephalopathy (HE). The aim of our study was investigate the relationship between muscle minimal HE (MHE) their role risk HE. Sixty-four patients with were administered Psychometric Hepatic Encephalopathy Score animal naming test detect MHE. Computed tomography used analyze skeletal index attenuation. incidence first episode HE, taking into account competing...
<h3>Introduction</h3> Hepatic macrophages (Kupffer cells) undergo inflammatory activation during the development of portal hypertension in experimental cirrhosis; this may play a pathogenic role or be an epiphenomenon. Our objective was to study serum soluble CD163 (sCD163), sensitive marker macrophage activation, before and after reduction venous pressure gradient by insertion transjugular intrahepatic portosystemic shunt (TIPS) patients with cirrhosis. <h3>Methods</h3> sCD163 measured 11...
Minimal hepatic encephalopathy (MHE) is a subclinical cognitive impairment frequently observable in patients with cirrhosis. Proton pump inhibitors (PPIs) can contribute to small‐bowel bacterial overgrowth, but no study has investigated the link between PPIs and MHE. We relationship MHE PPI use as well role of development overt HE survival. Consecutive cirrhosis (n = 310) were included followed up for 14.1 ± 12.3 months. At entry, was diagnosed when Psychometric Hepatic Encephalopathy Score...
Overt hepatic encephalopathy (OHE) is a major complication of transjugular intrahepatic portosystemic shunt (TIPS) placement, given its high incidence and possibility refractoriness to medical treatment. Nevertheless, the impact post-TIPS OHE on mortality has not been investigated in large population.
Background & AimsNumerous studies have evaluated the role of human albumin (HA) in managing various liver cirrhosis-related complications. However, their conclusions remain partially controversial, probably because HA was different settings, including indications, patient characteristics, and dosage duration therapy.MethodsThirty-three investigators from 19 countries with expertise complications were invited to organize an International Special Interest Group. A three-round Delphi consensus...
Helicobacter pylori eradication remains a challenge for physicians. Sequential, concomitant and the hybrid regimens have been proposed as novel, more effective therapies. We compare efficacy of these Dyspeptic patients referred upper endoscopy with H. infection were enrolled. Patients randomized to receive: (a) sequential therapy – 20 mg omeprazole 1 g amoxicillin 5 days, followed by omeprazole, 500 clarithromycin tinidazole successive days; (b) amoxicillin, either days (5 day concomitant)...