A5085229958- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Diverticular Disease and Complications
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Eosinophilic Esophagitis
- Tracheal and airway disorders
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Pancreatitis Pathology and Treatment
- Cancer, Lipids, and Metabolism
- Biliary and Gastrointestinal Fistulas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Appendicitis Diagnosis and Management
- Colorectal Cancer Surgical Treatments
- Liver Disease and Transplantation
- Inflammatory Bowel Disease
- Bariatric Surgery and Outcomes
- Liver Disease Diagnosis and Treatment
- Metastasis and carcinoma case studies
Maimonides Medical Center
2023-2025
Hospital Clínic de Barcelona
2021-2024
SUNY Downstate Health Sciences University
2023
GTx (United States)
2023
Albert B. Chandler Hospital
2021-2023
Johns Hopkins Hospital
2020-2022
Massachusetts General Hospital
2017-2022
Harvard University
2017-2021
Johns Hopkins University
2019-2021
Lemuel Shattuck Hospital
2021
The extent to which co-occurrence of cardiovascular disease (CVD) and cancer is due shared risk factors or other mechanisms unknown.We investigated the association standard CVD factors, biomarkers, preexisting CVD, ideal CV health metrics with development future cancer.We prospectively followed Framingham Heart Study PREVEND participants free at baseline, ascertained histology-proven cancer. We studied baseline 10-year atherosclerotic score, established prevalent AHA Life's Simple 7 score...
Main recommendations Malignant disease 1 ESGE recommends placement of partially or fully covered self-expandable metal stents (SEMSs) for palliation malignant dysphagia over laser therapy, photodynamic and esophageal bypass. Strong recommendation, high quality evidence. 2 brachytherapy as a valid alternative, alone in addition to stenting, cancer patients with expected longer life expectancy. 3 SEMS sealing tracheoesophageal bronchoesophageal fistulas. low 4 does not recommend bridge surgery...
Main Recommendations MR1 ESGE recommends the following standards for Barrett esophagus (BE) surveillance: – a minimum of 1-minute inspection time per cm BE length during surveillance endoscopy photodocumentation landmarks, segment including one picture length, and esophagogastric junction in retroflexed position, any visible lesions use Prague (for lesions) Paris classification collection biopsies from all abnormalities (if present), followed by random four-quadrant every 2-cm length. Strong...
Abstract Background/Aims Cirrhosis presents with variable degrees of thrombocytopenia that might cause bleeding during invasive procedures. Transfusion one standard adult platelet dose is often employed to prevent in thrombocytopenia, but the threshold count clinically effective not well established because clinical studies and laboratory tools judge on efficacy are insufficient. However, vitro showed patients cirrhosis generate as much thrombin healthy individuals provided their at least...
Although low fiber intake has been considered a risk factor for diverticulitis, prospective evidence is limited in women despite having disproportionate burden of disease, with little known about variation the protective effects according to food sources. We assessed associations intakes and major sources including fruits vegetables diverticulitis large cohort women.
<b>Background</b> Treatment of Zenker's diverticulum has evolved from open surgery to endoscopic techniques, including flexible and rigid septotomy, more recently, peroral myotomy (Z-POEM). This study compared the effectiveness septotomy with that Z-POEM. <b>Methods</b> Consecutive patients who underwent (flexible/rigid) or Z-POEM for between 1/2016 9/2019 were included. Primary outcomes clinical success (decrease in Dakkak Bennett dysphagia score ≤ 1), failure, recurrence. Secondary...
Most studies on endoscopic ultrasound (EUS)-guided gastroenterostomy (EUS-GE) for palliation of malignant gastric outlet obstruction (GOO) utilized a 15-mm lumen-apposing metal stent (LAMS). More recently, 20-mm LAMS has become available. This study aimed to compare rates technical and clinical success adverse events (AEs) in patients undergoing EUS-GE using vs. LAMS.Patients who underwent with or GOO during the period from January 2018 October 2020 were included. The primary outcome was...
To evaluate the value of serial C-reactive protein (CRP) measurements in predicting risk cardiovascular disease (CVD), cancer, and mortality. The analysis was performed using data from two prospective, population-based observational cohorts: Prevention Renal Vascular End-Stage Disease (PREVEND) study Framingham Heart Study (FHS). A total 9253 participants had CRP available at examinations (PREVEND: 1997-1998 2001-2002; FHS Offspring cohort: 1995-1998 1998-2001). All were natural...
Abstract Background Endoscopic resection of lesions involving the appendiceal orifice remains a challenge. We aimed to report outcomes with full-thickness device (FTRD) for and identify factors associated occurrence appendicitis. Methods This was retrospective study at 18 tertiary-care centers (USA 12, Canada 1, Europe 5) between November 2016 August 2020. Consecutive patients who underwent an lesion using FTRD were included. The primary outcome rate R0 in neoplastic lesions, defined as...
Obesity and cardiometabolic dysfunction have been associated with cancer risk severity. Underlying mechanisms remain unclear.The aim of this study was to examine associations obesity related traits incident cancer.FHS (Framingham Heart Study) PREVEND (Prevention Renal Vascular End-Stage Disease) participants without prevalent were studied, examining obesity, body mass index (BMI), waist circumference, visceral adipose tissue (VAT) subcutaneous depots, C-reactive protein (CRP) future in Cox...
Abstract Background Zenker’s peroral endoscopic myotomy (Z-POEM) is a novel procedure for the management of symptomatic diverticulum. This study aims to report technical feasibility and outcomes Z-POEM in diverticulum after prior failed interventions. Methods Patients with persistent or recurrent symptoms and/or surgical intervention were retrospectively included. The primary outcome was clinical success, defined as complete near resolution dysphagia (dysphagia score 0 1) without need repeat...