A5072479964- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Cardiac Ischemia and Reperfusion
- Adipose Tissue and Metabolism
- Receptor Mechanisms and Signaling
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Genetics, Aging, and Longevity in Model Organisms
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Nutrition and Health in Aging
- Frailty in Older Adults
- Particle physics theoretical and experimental studies
- Cardiovascular Disease and Adiposity
- Cardiac, Anesthesia and Surgical Outcomes
- Hormonal Regulation and Hypertension
- Intensive Care Unit Cognitive Disorders
- High-Energy Particle Collisions Research
- Cystic Fibrosis Research Advances
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
Istituto Nazionale di Fisica Nucleare, Sezione di Bari
2024-2025
University of Bari Aldo Moro
2023-2025
University of Naples Federico II
2015-2024
Federico II University Hospital
2014-2024
Polytechnic University of Bari
2024
University of Salerno
2024
Istituti Clinici Scientifici Maugeri
2013-2023
University of Palermo
2022
University of Ferrara
2003-2021
Hebrew University of Jerusalem
2021
The human endometrium undergoes a complex process of vascular and glandular proliferation, differentiation, regeneration with each menstrual cycle in preparation for implantation. Vascular endothelial growth factor (VEGF) is an cell-specific angiogenic protein that appears to play important role both physiological pathological neovascularization. To investigate whether VEGF may regulate endometrial angiogenesis, we examined messenger ribonucleic acid (mRNA) throughout the studied regulation...
Angiogenesis is important in the proliferation of inflammatory synovial tissue. Vascular endothelial growth factor (VEGF) an cell mitogen that also angiogenic vivo. We examined potential role VEGF mediating chemotaxis and cells rheumatoid arthritis (RA) using samples tissue fluid from 55 arthritic patients. Synovial by ELISA was higher RA fluids (386 +/- 122 ng/ml) (SE) compared with osteoarthritis (OA) (< 0.8 (p < 0.05) or patients other arthritides (6.6 2 ng/ml). In addition to its known...
The relationship between the consumption of meat and health is multifaceted, it needs to be analyzed in detail, with specific attention relevant differences that characterize effects different types, as yet considered by only a limited literature. A variable but moderate energy content, highly digestible proteins (with low levels collagen) good nutritional quality, unsaturated lipids (mainly found skin easily removed), B-group vitamins thiamin, vitamin B6, pantothenic acid), minerals (like...
To explore clinical phenotype and characteristics of Parkinson disease (PD) at different ages onset in recently diagnosed patients with untreated PD.We have analyzed baseline data from the Parkinson's Progression Markers Initiative database. Four hundred twenty-two a diagnosis PD confirmed by DaTSCAN imaging were divided into 4 groups according to age (onset younger than 50 years, 50-59 60-69 70 years or older) investigated for differences side, type localization symptoms,...
To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number participants these not exceeded a few hundred. overcome limitations, we have determined, multicenter study, over single day large population patients admitted to and rehabilitation wards Italy. This is point study (called "Delirium Day") including 1867 older (aged 65 years or more) across...
<h3>Objective</h3> To investigate whether diabetes mellitus is associated with Parkinson-like pathology in people without Parkinson disease and to evaluate the effect of on markers clinical progression drug-naive patients early-stage disease. <h3>Methods</h3> We compared 25 mellitus, 14 no healthy controls (people or disease). The diagnosis was confirmed by 2 consecutive fasting measurements serum glucose levels >126 mL/dL. Over a 36-month follow-up period, we then investigated population...
To determine whether the angiogenic peptide vascular endothelial growth factor (VEGF) is sufficient to produce iris neovascularization in a nonhuman primate (Macaca fascicularis).Eight eyes of 4 animals were studied. The 165-amino acid isoform human recombinant VEGF (VEGF165) was injected into vitreous 5 cynomolgus monkey (doses ranging from 0.25-2.5 micrograms per injection). Equal amounts inactivated (2 eyes) or vehicle (1 eye) contralateral control eyes. Eyes assessed by slitlamp...
Abstract Background The elderly are characterized by a high prevalence of chronic heart failure (CHF) and frailty, which is complex interaction physical, psychological social impairment. This study aimed to examine the predictive role frailty on long‐term mortality in subjects with CHF. Materials methods assessed after 12‐year follow up 120 CHF 1139 without CHF, selected 1992, from random sample population Campania region Italy. Frailty was according ‘Frailty Staging System’. Results...
We studied the distribution of messenger RNA (mRNA) that encodes for vascular endothelial growth factor (VEGF) within primate ovary by in situ hybridization and Northern analysis to determine if presence mRNA this angiogenic is associated with structures which angiogenesis thought play a role development and/or function. In sections cynomolgus ovaries 35S-labeled antisense probe revealed specific tissue localization follicle as well corpus luteum, but not stromal tissue. Intense expression...
The objective of this study was to determine the effects aging and exercise training on SIRT1 activity identify a pathway linking antioxidant response cell cycle regulation in rats. is NAD+-dependent deacetylase involved oxidative stress aging. moderate prolonged rats are unknown. We measured heart adipose tissue young (6 months old), sedentary old (24 months), trained months) using an assay kit. Peroxidative damage determined by measuring levels thiobarbituric reactive substances (TBARS)...
OBJECTIVE: Congestive heart failure (CHF) is potentially preventable, and the identification of modifiable risk factors for cognitive impairment (CI) older persons a very important issue. We examined cross‐sectional relationship between CHF CI in an population. DESIGN: A survey. SETTING AND PARTICIPANTS: total 1339 subjects aged 65 were selected from electoral rolls Campania, region southern Italy. MEASUREMENTS: Sociodemographic characteristics recorded, as was presence cardiovascular...
Cultured monolayers of bovine pituitary follicular cells, which transport ions, contain high amounts mitogenic activity for endothelial cells which, on the basis gene expression analysis, heparin-Sepharose elution profile, bioassay, immunoblotting, radioimmunoassay, and radioreceptor assay, has been identified as basic fibroblast growth factor (bFGF). These data indicate that may be a major source bFGF in gland. Considering proposed to play role paracrine regulation hormone secretion, also...
Objective. During OMERACT 8, delegates selected patient global assessment (PGA) of disease as a domain to be evaluated in randomized controlled trials psoriatic arthritis (PsA). This study assessed the reliability PGA, measured by means 0–100 mm visual analog scale (VAS), and additional utility separate VAS scales for joints (PJA) skin (PSA). Methods. In total, 319 consecutive patients with PsA (186 men, 133 women, mean age 51 ± 13 yrs) were enrolled. PJA, PSA administered at enrolment (W0)...