Francesco Cacciatore
- Heart Failure Treatment and Management
- Frailty in Older Adults
- Cardiac Ischemia and Reperfusion
- Cardiovascular Function and Risk Factors
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Transplantation: Methods and Outcomes
- Blood Pressure and Hypertension Studies
- Cardiac Arrest and Resuscitation
- Renal Transplantation Outcomes and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- Dementia and Cognitive Impairment Research
- Cardiac pacing and defibrillation studies
- Anesthesia and Neurotoxicity Research
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Organ Transplantation Techniques and Outcomes
- Cardiac electrophysiology and arrhythmias
- Body Composition Measurement Techniques
- Chronic Disease Management Strategies
- COVID-19 Clinical Research Studies
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
Federico II University Hospital
2008-2025
University of Naples Federico II
2015-2024
Ospedale Monaldi
2017-2022
Regione Campania
2021
IberEspacio (Spain)
2021
Azienda Ospedaliera San Gerardo
2020
University of Padua
2020
Fondazione Salvatore Maugeri
2009-2018
Istituti Clinici Scientifici Maugeri
2001-2018
Politecnico di Milano
2014-2018
Abstract Background The elderly are characterized by a high prevalence of chronic heart failure (CHF) and frailty, which is complex interaction physical, psychological social impairment. This study aimed to examine the predictive role frailty on long‐term mortality in subjects with CHF. Materials methods assessed after 12‐year follow up 120 CHF 1139 without CHF, selected 1992, from random sample population Campania region Italy. Frailty was according ‘Frailty Staging System’. Results...
<i>Background:</i> Hearing impairment (HI) is a very common condition in elderly people and the epidemiology together with hearing-related problems still poorly investigated. Moreover, cognitive status may be impaired relation to hearing function. <i>Objective:</i> The goal of study was evaluate: (a) prevalence HI random sample aged 65 over (n = 1,750) living Campania, region southern Italy; (b) cross-sectional relationship between function also depressive...
OBJECTIVE: Congestive heart failure (CHF) is potentially preventable, and the identification of modifiable risk factors for cognitive impairment (CI) older persons a very important issue. We examined cross‐sectional relationship between CHF CI in an population. DESIGN: A survey. SETTING AND PARTICIPANTS: total 1339 subjects aged 65 were selected from electoral rolls Campania, region southern Italy. MEASUREMENTS: Sociodemographic characteristics recorded, as was presence cardiovascular...
Abstract Introduction A hypercoagulable condition was described in patients with coronavirus disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing to progression lethality. Aim We evaluated if in-hospital administration of heparin improved survival large cohort Italian COVID-19 patients. Methods In retrospective observational study, 2,574 unselected hospitalized 30 clinical centers Italy from February 19, 2020 June 5, laboratory-confirmed severe acute...
Abstract Selection of cancer patients for treatment with immune checkpoint inhibitors remains a challenge due to tumour heterogeneity and variable biomarker detection. PD-L1 expression in 24 surgical chordoma specimen was determined immunohistochemically antibodies 28-8 E1L3N. The ability patient-derived organoids detect effects nivolumab explored by quantitative qualitative immunofluorescence FACS analysis. more sensitive antibody, E1L3N (ROC = 0.896, p 0.001), associated greater diameters...
ABSTRACT— An epidemiological survey of the prevalence snoring and sleep apnoeas was performed on 3479 30-69-year-old men living in Bologna, north-east Italy. First a postal questionnaire sent. It returned with appropriate answers by 1170. A 20% random sample those who did not answer were invited telephone to return questionnaire. Among these groups 119 (10%) 19 (5.6%) respectively answered that they always snored. 40 every-night snorers studied polysomnography. Based frequency results...
Objective The aim of this study was to investigate the cross-sectional relationship between arterial blood pressure and cognitive impairment in a group elderly subjects, controlling for such confounding variables as age, education, depression, drug use antihypertensive treatment. Design setting A survey Campania, region southern Italy. Subjects methods random sample 1339 subjects aged 65–95 years (mean 73.9 ± 6.2 years) selected from electoral rolls interviewed by trained physicians....
Tumor growth requires neoangiogenesis. VEGF is the most potent proangiogenic factor. Dysregulation of hypoxia-inducible factor (HIF) or cytokine stimuli such as those involving chemokine receptor 4/stromal-derived cell 1 (CXCR4/SDF-1) axis are major cause ectopic overexpression in tumors. Although CXCR4/SDF-1 pathway well characterized, transcription factors executing effector function this signaling poorly understood. The multifunctional Yin Yang (YY1) protein highly expressed different...
Background: The role of ventricular rate response (VRr) on the incidence dementia in elderly subjects with cognitive impairment and atrial fibrillation (AF) is not known. Thus, we examined ability VRr to predict cognitively impaired without AF. Methods: A total 358 (MMSE <24) AF were stratified low/high (<50/>90) moderate (>50/<90 bpm) VRr. 10-year follow-up was performed. Results: Cognitively at end 135 (37.7%): 33 presence (75.0%) 102 (32.5%) absence (p < 0.001). Multivariate analysis...