A5012973305- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Frailty in Older Adults
- Diabetes Management and Research
- Cardiac Arrest and Resuscitation
- Chronic Disease Management Strategies
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 and healthcare impacts
- Thermal Regulation in Medicine
- Pancreatitis Pathology and Treatment
- Medication Adherence and Compliance
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Potassium and Related Disorders
- Lipid metabolism and disorders
- Cerebral Venous Sinus Thrombosis
- Renin-Angiotensin System Studies
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2019-2024
University of Chieti-Pescara
1998-2023
Azienda Ospedaliera Universitaria Senese
2023
Policlinico S.Orsola-Malpighi
2023
Ospedale San Paolo
2023
IRCCS Ospedale San Raffaele
2023
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2023
Ospedale SS. Annunziata
2023
University of Parma
2021
Mario Negri Institute for Pharmacological Research
2020
The ability of interleukin (IL)-12 to prevent tumors when administered individuals with a genetic risk cancer was studied in two lines transgenic mice expressing rat HER-2/neu oncogene the mammary gland. Female BALB/c (H-2d) carrying activated HER-2/ neu show no morphological abnormalities gland until 3 wk age. They then progress through atypical hyperplasia situ lobular carcinoma and at 33 age all 10 glands display invasive carcinomas. Adult FVB (H-2q) protooncogene develop carcinomas...
The renin-angiotensin system (RAS) plays a main role in regulating blood pressure and electrolyte liquid balance. Previous evidence suggests that RAS may represent an important target for the treatment of lung pathologies, especially acute respiratory distress syndrome chronic fibrotic disease. scientific community has recently focused its attention on angiotensin-converting enzyme (ACE) inhibitors angiotensin receptor 1 (AT1R) their possible benefit/harms patients infected by Coronavirus...
COVID-19 patients may manifest thrombocytopenia and some of these succumb to infection due coagulopathy. The aim our study was examine platelet count values in infected with SARS-CoV-2, comparing them a control group consisting non-COVID-19 patients. Moreover, we evaluated the correlation between value respiratory alteration parameters outcome (hospitalization mortality) mean (×109/L) differed positive or negative SARS-CoV-2 swabs (242.1 ± 92.1 vs. 215.2 82.8 patients, p < 0.001). In...
OBJECTIVES:The sero-prevalence of co-infection with the hepatitis B virus (HBV) and D (HDV) is well known in many European countries, starting from 6.8% Germany to more than 27% some Turkish areas. To gain a better description this infection Switzerland, characterise those affected, questionnaire was sent all Swiss gastroenterologists, hepatologists infectologists. METHODS:A received by 349 physicians which asked them report on HBV- HDV-infected patients seen at their units/offices....
The diffusion of SARS-CoV-2, starting from China in December 2019, has led to a pandemic, reaching Italy February 2020. Previous studies Asia have shown that the median duration SARS-CoV-2 viral shedding was approximately 12–20 days. We considered cohort patients recovered COVID-19 showing disease between onset and end symptoms 27.5 days (interquartile range (IQR): 17.0–33.2) microbiological healing, defined by two consecutive negative nasopharyngeal swabs, 38 (IQR: 31.7–50.2). A longer with...
In December 2019, an outbreak of a new coronavirus (SARS-CoV-2) was reported in Hubei province China. The disease has since spread worldwide and the World Health Organization declared it pandemic on 11 March 2020. We describe case 65-year-old woman who clinically recovered from COVID-19 but showed persistent infection with SARS-CoV-2 for 51 days.
We present a case in which lung ultrasound (LUS) was relevant to reach an early diagnosis of tuberculosis and manage the patient right setting. Moreover, allowed detect treat massive pleural effusion through ultrasound-guided thoracentesis.
Background and Objectives: Obesity is a worldwide disease associated with systemic complications. In recent years, there has been growing interest in studying vitamin D but data related to obese subjects are still poor. AIM: The aim of this study was evaluate the relationship between obesity degree 25-hydroxyvitamin [25(OH)D] levels. Materials Methods: We recruited 147 Caucasian adult patients (BMI > 30 Kg/m2; 49 male; median age 53 years), 20 overweight as control group (median 57 who had...
It seems that during SARS-CoV-2 infection, total cholesterol, LDL-C, and HDL-C values decrease lipids could play a fundamental role in viral replication. Moreover, it has been shown infection influence thyroid function. We performed retrospective analysis of 118 hospitalized patients with COVID-19, comparing pre-infection lipid profile (53 patients) thyroid-stimulating hormone (TSH) (45 to those measured on admission. Our aim was evaluate whether be involved alterations study possible...
Non-alcoholic fatty liver disease (NAFLD) is the most widespread disease, characterized by acids accumulation and subsequent fibrosis. NAFLD prevalence ranges from 80% to 90% in obese subjects estimated be around 50% patients with metabolic syndrome. In this clinical scenario, diet lifestyle modifications can play an important role. There are several imaging techniques that accurately diagnose liver. Recently, ultrasound has acquired a leading role diagnosis follow-up of disease....
Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of hospitalization and several geriatric syndromes than older nondiabetic adults. For these conditions, special care required prescribing therapies including anti- diabetes drugs. Aim this study was to evaluate appropriateness adherence safety recommendations prescriptions glucose-lowering drugs hospitalized patients diabetes. Data for...
Outcomes of insulin analogues in pediatric diabetes camps are poorly investigated; no data is available about degludec (IDeg).Our aim was to assess impact therapy adopted by the participants a 4-day camp held 2017, hypothesizing possible excess risk hypoglycemia patients treated with IDeg. Overall, 40 children type 1 (mean age 13.4±3.0 years; 62.5% males) attended (20.0% on continuous subcutaneous infusion and 80.0% multiple daily injections - MDI). Among MDI regimen, 71.9% were IDeg as...
Background Fever occurs frequently in acute brain injury patients, and its occurrence is associated with poorer outcomes. Paracetamol, an antipyretic employed patients cerebral damage, may cause hypotension. We evaluated the hemodynamic effects of intravenous (IV) paracetamol for control fever Neuro-Intensive Care Unit (NICU) patients.
The efficacy of hydroxychloroquine (HCQ) in treating SARS-CoV-2 infection is harshly debated, with observational and experimental studies reporting contrasting results. To clarify the role HCQ Covid-19 patients, we carried out a retrospective study 4,396 unselected patients hospitalized for Italy (February–May 2020). Patients’ characteristics were collected at entry, including age, sex, obesity, smoking status, blood parameters, history diabetes, cancer, cardiovascular chronic pulmonary...
Currently, Italian versions of the Hypoglycemia Fear Survey for Children (CHFS) and Parents (PHFS) quantifying (FoH) in pediatric diabetes are not available.To validate version CHFS PHFS.One hundred seventy-four children with type 1 aged 6-18 178 parents completed PHFS, PedsQL 3.0 Diabetes module KIDSCREEN-10. Internal consistency was good (α = 0.85 CHFS, α 0.88 PHFS); validity supported by correlations total score (CHFS-T r -0.50; p < 0.001, CI -0.62 to -0.35) Worry subscale (CHFS-W -0.49;...