A5082342562- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Immunodeficiency and Autoimmune Disorders
- Cytomegalovirus and herpesvirus research
- Chronic Lymphocytic Leukemia Research
- Pediatric Hepatobiliary Diseases and Treatments
- Mycobacterium research and diagnosis
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Diverticular Disease and Complications
- Gastrointestinal Tumor Research and Treatment
- Eosinophilic Esophagitis
- SARS-CoV-2 and COVID-19 Research
- Helicobacter pylori-related gastroenterology studies
- Acute Lymphoblastic Leukemia research
- Gut microbiota and health
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- Digestive system and related health
- Gastrointestinal motility and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal and Anal Carcinomas
Policlinico S.Orsola-Malpighi
2018-2025
University of Bologna
2017-2024
Azienda USL di Bologna
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Abstract Background Cytomegalovirus (CMV) colitis is a serious concern worsening the prognosis of patients with ulcerative (UC) as an independent risk factor for hospitalization and surgery. European guidelines indicate that immunohistochemistry [IHC], tissue polymerase chain reaction [PCR], or possibly both, are essential confirming active CMV in IBD should be considered standard tests. The aim our study to evaluate diagnostic performance different tests used diagnosis infection comparison...
Abstract Background A new capsule endoscopy (CE) system featuring two advanced optics for 344°-viewing and a prolonged operative time has been recently developed Crohn’s disease (CD) patients. Hence, we evaluated, the first time, performance of this novel CE add-on value in multi-center real-life setting. Methods Consecutive patients with suspected or established CD received PillCam™ System as supplementary diagnostic work-up focused on small-bowel between June 2017 2018. Technical clinical...
Background COVID-19, whose causative pathogen is the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), was declared a pandemic in March 2020. The gastrointestinal tract one of targets this virus, and mounting evidence suggests that symptoms may contribute to disease severity. gut–lung axis involved immune response SARS-CoV-2; therefore, we investigated whether COVID-19 patients’ bacterial fungal gut microbiome composition linked clinical outcome. Methods In May 2020, collected...
Abstract Background Crohn’s disease (CD) can be classified according to endoscopic and cross-sectional imaging characteristics. Information regarding extent phenotype may provided by advanced techniques. In this study, we compare the ability of capsule endoscopy (CE) techniques (CST) (MRE/Computer Tomography Enteroscopy [CTE]) in detecting small bowel (SB) lesions. Methods We retrospectively analyzed 102 patients with a diagnosis CD who underwent both CE CST. Only at least 12-month follow-up...
Over the past few years, COVID-19 pandemic has imposed a high toll worldwide, with burden of morbidity and mortality. Healthcare practitioners (HCPs) have been in frontline since beginning outbreak, level stress affected their physical mental status, as well relationships. We aimed at exploring self-reported changes comprehensive well-being cohort Italian physicians. An online-based survey was administered to members Society Internal Medicine (SIMI) between March June 2021. The based on 32...
Abstract Background Cytomegalovirus (CMV) colitis is a serious concern worsening the prognosis of patients with ulcerative (UC), involving mainly those who are not responding to immunosuppressive therapy. CMV an independent predictor hospitalisation and surgery. Diagnosis can be obtained either via immunohistochemistry (ICH) or tissue polymerase chain reaction (PCR), possibly both. We aimed assess prognostic impact in UC clinical utility testing for plasma-DNA reactivation. Methods conducted...
ABSTRACT Cytomegalovirus (CMV) colitis is a serious concern worsening the prognosis of patients with ulcerative (UC). We aimed to assess risk factors and prognostic impact CMV in moderate-to-severe UC flare. conducted retrospective, observational, single-center study. Consecutive adult hospitalized for from January 2020 June 2023 were included. The primary endpoint was diagnosis CMV-colitis according immunohistochemistry on tissue biopsies. secondary need colectomy within 30 days. Overall,...
Abstract Background Long-term effectiveness of vedolizumab (VDZ) in real-life clinical practice is unknown. We aimed to evaluate efficacy and treatment persistence VDZ a real-world cohort patients with Crohn’s disease (CD). Methods CD from single tertiary IBD referral centre receiving outside trials between September 2016 August 2019 were included. Data collected prospectively at baseline, weeks 22, 54, 108. Disease activity was assessed using the Harvey Bradshaw index (HBI). The primary...
Background: Large bowel localization of Crohn's disease occurs in more than 60% all patients. In approximately 50% those patients small coexists, while the other half, colon is only localization. Rectum involved about 40% At least 30% with colonic Crohn' will require surgery during their lifetime. For extensive first-choice surgical therapy consist rectum sparing colectomy and ileorectal anastomosis. this study we evaluated long-term outcome ileo-rectal anastomosis relatively to prior...