A5046989874- Systemic Sclerosis and Related Diseases
- Dermatologic Treatments and Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diagnosis and Treatment of Venous Diseases
- Inflammatory Myopathies and Dermatomyositis
- Salivary Gland Disorders and Functions
- Venous Thromboembolism Diagnosis and Management
- Body Contouring and Surgery
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Connective Tissue Growth Factor Research
- Systemic Lupus Erythematosus Research
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Dermatological and Skeletal Disorders
- Cardiovascular Disease and Adiposity
- Autoimmune Bullous Skin Diseases
- Eosinophilic Esophagitis
- Acute Ischemic Stroke Management
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular and Diving-Related Complications
- COVID-19 Clinical Research Studies
- Lymphatic System and Diseases
- Celiac Disease Research and Management
- Asthma and respiratory diseases
Azienda Ospedaliera di Cosenza
2022-2023
Istituto Ortopedico Gaetano Pini
2016-2021
Azienda Socio Sanitaria Territoriale Lariana
2020
Ferrari (Italy)
2020
Università Campus Bio-Medico
2015-2018
Imperial College London
2017
Foro Italico University of Rome
2017
Sapienza University of Rome
2013-2014
Policlinico Umberto I
2011
University of Bologna
1998
A randomized controlled trial (RCT) was performed to confirm preliminary uncontrolled data indicating that regional adipose tissue (AT) grafting (G) is effective in inducing ischemic digital ulcer (IDU) healing patients with systemic sclerosis (SSc). SSc IDUs were be blindly treated AT-G or a sham procedure (SP). consisted of injection, at the base finger IDU, 0.5–1 ml AT after centrifugation fat aspirate. The SP false liposuction and local injection saline solution. primary endpoint compare...
This study aims to assess the peripheral blood cell count “signature” of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) discriminate promptly between COronaVIrus Disease 19 (COVID-19) and community-acquired pneumonia (CAP). We designed a retrospective case-control study, enrolling 525 patients (283 COVID-19 242 with CAP). All had fever at least one following signs: cough, chest pain, or dyspnea. excluded treated immunosuppressants, steroids, affected by diseases known modify...
Mesenchymal stromal cells (MSCs) have received attention as an ideal source of regenerative because their multipotent differentiation potential. Adipose tissue is attractive MSCs. Recent studies shown that autologous fat grafting may be effective in the treatment systemic sclerosis (SSc), but no specific study exists aimed at investigating whether adipose tissue-derived (ADSCs) from SSc patients maintain normal phenotypic and functional characteristics. The purpose current was to investigate...
Some abnormalities in nailfold videocapillaroscopy (NVC), such as the presence of micro-haemorrhages (MHEs), micro-thromboses (MTs), giant capillaries (GCs) and reduction number (nCs), suggest a disease activity (DA) phase systemic sclerosis (SSc). In previous paper, we showed that (the so-called NEMO score) was NVC feature more closely associated with DA. The present study aimed at validating score measure DA patients SSc. Two cohorts 122 97 SSc who were referred to two different...
Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated systemic sclerosis (SSc). Recent insights have also highlighted its role in diagnostic idiopathic inflammatory myopathies (IIMs). The aim this study to describe NVC a series 361 consecutive interstitial lung disease (ILD). All were assessed by clinical pulmonary and rheumatic examinations, blood exams, high-resolution computed tomography NVC. was...
Mortality rate in patients infected by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can be related to the presence of comorbidities like diabetes, cardiovascular and pulmonary diseases. On contrary, few data exist on impact CoronaVirus Disease 2019 (COVID-19) with rheumatic disorders, namely those having involvement treated immunosuppressive agents. The present survey is aimed at knowing COVID-19 a cohort systemic sclerosis (SSc).Telephone interviews were carried out during...
Abstract Background In previous studies, we demonstrated that the NEMO score, i.e. cumulative number of microhaemorrhages (MHEs) and microthromboses (MTs), observed in nailfold videocapillaroscopy was a good indicator steady state level disease activity (DA) patients with systemic sclerosis (SSc) when European Scleroderma Study Group (EScSG) index considered gold standard. Aim study To verify whether score could be (i) valid tool to assess DA, even modified Trials Research (EUSTAR)...
Severe morning stiffness with painful involvement of the girdles are often referred by patients Interstitial Lung Disease (ILD), but association between ILD and Polymyalgia Rheumatica (PMR) is rarely reported. The purpose work to describe a series classified as having PMR ILD. We retrospectively enrolled diagnosis our center during previous year for respiratory symptoms. Data concerning clinical serological manifestations suggesting Connective Tissue (CTD), High-Resolution Chest Tomography...
Over the past few years, COVID-19 pandemic has imposed a high toll worldwide, with burden of morbidity and mortality. Healthcare practitioners (HCPs) have been in frontline since beginning outbreak, level stress affected their physical mental status, as well relationships. We aimed at exploring self-reported changes comprehensive well-being cohort Italian physicians. An online-based survey was administered to members Society Internal Medicine (SIMI) between March June 2021. The based on 32...
COVID-19 outbreak has quickly spread worldwide, causing a high pressure on the health-care system. In Italy, from March 8, 2020, all deferrable clinical activities have been suspended to increase health care offer for patients. The hospital organization modified also in order assure non-COVID-19 patients assistance. Scleroderma Unit of ASST Pini-CTO Hospital, Milan, region mostly hit by SARS-CoV-2 follows more than 600 affected systemic sclerosis (SSc). Patients with SSc need close follow-up...
To investigate the gene expression profile in patients with Sjögren's syndrome that is characterized by different clinical phenotypes.RNA from peripheral blood mononuclear cells was purified 8 glandular features (GFs) and widespread pain (WP) 11 extraglandular manifestations (EGMs) then analyzed hybridization on a human chip exploring more than 40,000 genes. Differentially expressed genes (DEGs) two subgroups (ie, those false discovery rate-corrected P values ≤ 0.01) respect to 20 healthy...