Andrea Salzano
A5058260855- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Effects of Exercise
- Hormonal and reproductive studies
- Nutrition and Health in Aging
- Cardiovascular and exercise physiology
- Diet and metabolism studies
- Growth Hormone and Insulin-like Growth Factors
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Cardiac Imaging and Diagnostics
- Genetic Neurodegenerative Diseases
- Cardiac pacing and defibrillation studies
- Cardiac Health and Mental Health
- Cardiovascular Issues in Pregnancy
- Pharmaceutical Practices and Patient Outcomes
- Cardiac Valve Diseases and Treatments
- Mitochondrial Function and Pathology
- Cardiac Fibrosis and Remodeling
- Pediatric Hepatobiliary Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Gut microbiota and health
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
Federico II University Hospital
2015-2025
University of Leicester
2017-2024
Glenfield Hospital
2017-2024
Ospedale Antonio Cardarelli
2022-2024
University of Naples Federico II
2008-2024
NIHR Leicester Biomedical Research Centre
2017-2023
Policlinico Umberto I
2023
SDN Istituto di Ricerca Diagnostica e Nucleare
2019-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
Synlab Czech (Czechia)
2022
Abstract Aim To investigate the prevalence and prognostic impact of right heart failure ventricular-arterial uncoupling in Corona Virus Infectious Disease 2019 (COVID-19) complicated by an Acute Respiratory Distress Syndrome (ARDS). Methods Ninety-four consecutive patients (mean age 64 years) admitted for acute respiratory on COVID-19 were enrolled. Coupling ventricular function to pulmonary circulation was evaluated a comprehensive trans-thoracic echocardiography with focus tricuspid...
Background Although mounting evidence supports the concept that growth hormone (GH) deficiency (GHD) affects cardiovascular function, no study has systematically investigated its prevalence and role in a large cohort of chronic heart failure (CHF) patients. Aim this is to assess GHD mild-to-moderate CHF explore clinical functional correlates GHD. Methods One-hundred thirty patients underwent GH provocative test with GHRH+arginine accordingly categorized into GH-deficiency (GHD, n = 88, age...
Recent evidence supports the occurrence of multiple hormonal and metabolic deficiency syndrome (MHDS) in chronic heart failure (CHF). However, no large observational study has unequivocally demonstrated its impact on CHF progression outcome. The T.O.S.CA. (Trattamento Ormonale nello Scompenso CArdiaco; Hormone Treatment Heart Failure) Registry been specifically designed to test hypothesis that MHDS affects morbidity mortality patients.The is a prospective, multicentre, involving 19 Italian...
PATIENTS with classic congenital adrenal hyperplasia (CAH) are treated lifelong glucocorticoids (GCs). Cardiovascular and metabolic effects of such therapy in adolescents have never been quantified.Our objective was to investigate left ventricular (LV) morphology, function, exercise performance CAH.We conducted a cross-sectional controlled study at tertiary referral center.Twenty patients CAH (10 females) aged 13.6 ± 2.5 years 20 healthy controls comparable for sex pubertal status were...
Abstract Aims The aim of this study was to investigate whether ethnicity influences the associations between trimethylamine N‐oxide (TMAO) levels and heart failure (HF) outcomes. Methods results Trimethylamine were measured in two cohorts with acute HF at sites. UK Leicester cohort consisted mainly Caucasian ( n = 842, 77%) South Asian 129, 12%) patients, whereas patients Japanese 116, 11%) all Japanese. primary endpoint measurement all‐cause mortality and/or rehospitalization within 1 year...
Pulmonary arterial hypertension (PAH) is a rare subtype of group 1 pulmonary (PH) diseases, characterized by high artery pressure leading to right ventricular dysfunction and potential life-threatening consequences. PAH involves complex mechanisms: vasoconstriction, vascular remodeling, endothelial dysfunction, inflammation, oxidative stress, fibrosis, RV cellular hypoxia, metabolic imbalance, thrombosis. These mechanisms are mediated several pathways, involving molecules like nitric oxide...
Growing evidence suggests that reduced activity of the growth hormone (GH)/insulin-like factor (IGF)-1 axis is common and associated with poor clinical status outcome in heart failure (HF). In addition, preliminary results deficiency (GHD) correction HF showed an improvement quality life, cardiac structure function, cardiovascular performance. The aim present double-blind, randomized, placebo-controlled trial was to evaluate effects 1 year GH replacement therapy a cohort patients ejection...