A5090731125- Cardiac Health and Mental Health
- Cardiovascular and exercise physiology
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Heart Rate Variability and Autonomic Control
- Ovarian function and disorders
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Nutrition and Health in Aging
- Hormonal and reproductive studies
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Frailty in Older Adults
- Cardiovascular Health and Disease Prevention
- Hormonal Regulation and Hypertension
- Iron Metabolism and Disorders
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer survivorship and care
- Erythropoietin and Anemia Treatment
- Bone health and osteoporosis research
- Blood Pressure and Hypertension Studies
University of Naples Federico II
2016-2025
Federico II University Hospital
2016-2025
University of New England
2012-2023
University of Campania "Luigi Vanvitelli"
2023
Ospedale Veris Delli Ponti Scorrano
2016
University of Parma
2016
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2016
St George's, University of London
2014
University of Padua
2014
National Institute on Aging
2008-2013
Introduction: Several established tools are available to assess study quality and reporting of randomized controlled trials; however, these were designed with clinical intervention trials in mind. In exercise training some the traditional criteria, such as participant or researcher blinding, extremely difficult implement. Methods: We developed Tool for assEssment Study qualiTy EXercise (TESTEX) – a assessment tool, specifically use studies. Our tool is 15-point scale (5 points 10 reporting)...
BACKGROUNDLifestyle modifications are successfully employed to treat obese and overweight women with polycystic ovary syndrome (PCOS). The aims of the current pilot study were (i) compare efficacy on reproductive functions a structured exercise training (SET) programme diet in PCOS patients (ii) their clinical, hormonal metabolic effects elucidate potentially different mechanisms action.
Polycystic ovary syndrome (PCOS) is an endocrine disease closely related to several risk factors for cardiovascular disease. An impaired cardiopulmonary functional capacity was previously demonstrated in PCOS women. No data regarding the effects of a structured exercise training (ET) program on women are available.Our objective evaluate 3-month ET young women.A prospective baseline-randomized clinical study conducted at University "Federico II" Naples, School Medicine (Italy).Ninety...
BACKGROUNDWomen with polycystic ovary syndrome (PCOS) have been reported to subclinical cardiovascular disease (CVD) and increased abdominal fat. The aim of this study was evaluate the relationship between visceral fat (VF) early markers CVD in PCOS women.
Abstract Aims No data are available on early initiation of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) in patients with acute coronary syndrome (ACS) the real world. This study investigates effects PCSK9i started at time ACS hospitalization lipid control and major cardiovascular (CV) events Methods results The outcome was percentage reaching LDL-C target <55 mg/dL first control. clinical incidence composite CV (all-cause death, non-fatal MI, stroke,...
Dopamine is a key neurotransmitter involved in physiological processes such as motor control, motivation, reward, cognitive function, and maternal reproductive behaviors. Therefore, dysfunctions of the dopaminergic system are related to plethora human diseases. Dopamine, via different circuitries implicated compulsive behavior, habit formation, also represents player substance use disorder formation perpetuation mechanisms leading addiction. Here, we propose dopamine model not only...
Background/Objectives: This study assessed the proportion of secondary cardiovascular prevention patients who achieved low-density lipoprotein (LDL) cholesterol targets as per 2019 ESC/EAS Dyslipidemia Guidelines. We also evaluated whether lipid-lowering therapies (LLTs) were adjusted in not meeting and analyzed likelihood these modifications achieving recommended levels. Methods: A multicenter, cross-sectional observational retrospectively reviewed medical records 1909 outpatients 9 Italian...
Abstract Context: Polycystic ovary syndrome (PCOS) is associated with early impairment of vascular structure and a low-grade chronic inflammation. Aldosterone well-recognized cardiovascular risk (CVR) factor related to inflammatory processes. Objective: Our objective was investigate serum aldosterone levels in PCOS correlate them some CVR factors atherosclerotic markers. Design Setting: A prospective baseline-controlled clinical study conducted at the University “Federico II” Naples School...
Clomiphene citrate (CC) is the first-line therapy for induction of ovulation in infertile women with polycystic ovary syndrome (PCOS), but ∼20% patients are unresponsive. The aim current study was to test hypothesis that a 6-week intervention consisted structured exercise training (SET) and hypocaloric diet increases probability after CC overweight obese CC-resistant PCOS patients.A cohort 96 enrolled consecutively three-arm randomized, parallel, controlled, assessor-blinded clinical trial....
Polycystic ovary syndrome (PCOS) is a common female reproductive-age endocrine disease predominantly characterized by chronic anovulation, hyperandrogenism, insulin-resistance and low-grade inflammatory status. Exercise training (ET) favourably modulates cardiopulmonary function insulin-sensitivity markers in PCOS women. The present study investigated the effects of ET on autonomic pattern women.Prospective baseline uncontrolled clinical study.One-hundred eighty five women referred to our...
The importance of vitamin D for bone health has long been acknowledged. Recent evidence suggests that can also play a role in reducing the risk several other diseases, including cardiovascular disease.The aim this study is to test hypothesis 25-hydroxyvitamin (25-OH D) an independent cross-sectional correlate central arterial stiffness normative aging population.We conducted analysis.We studied 1228 healthy volunteers (50% males; age, 70±12 yr) Baltimore Longitudinal Study Aging.We measured...
Poor muscle strength is a major public health concern in older persons, predisposing to functional limitations, increased fall risk, and higher mortality. Understanding risk factors for decline may offer opportunities prevention treatment. One of the possible causes imbalance between catabolic anabolic signaling. This study aims examine whether high levels multiple low biomarkers predict accelerated strength.In representative sample 716 men women aged >or=65 years InCHIANTI we measured...
Background Although mounting evidence supports the concept that growth hormone (GH) deficiency (GHD) affects cardiovascular function, no study has systematically investigated its prevalence and role in a large cohort of chronic heart failure (CHF) patients. Aim this is to assess GHD mild-to-moderate CHF explore clinical functional correlates GHD. Methods One-hundred thirty patients underwent GH provocative test with GHRH+arginine accordingly categorized into GH-deficiency (GHD, n = 88, age...