A5010920275- Parkinson's Disease Mechanisms and Treatments
- Nutrition and Health in Aging
- Frailty in Older Adults
- Intensive Care Unit Cognitive Disorders
- Neurotransmitter Receptor Influence on Behavior
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Neuroscience and Neuropharmacology Research
- Enhanced Recovery After Surgery
- Ultrasound in Clinical Applications
- Atrial Fibrillation Management and Outcomes
- Health Promotion and Cardiovascular Prevention
- Aging and Gerontology Research
- Vitamin C and Antioxidants Research
- Historical and modern epidemiology studies
- Genetic Neurodegenerative Diseases
- Respiratory Support and Mechanisms
- Restless Legs Syndrome Research
- Receptor Mechanisms and Signaling
- Vitamin D Research Studies
- Pleural and Pulmonary Diseases
- Cardiovascular Function and Risk Factors
- Sleep and Wakefulness Research
- Functional Brain Connectivity Studies
University of Parma
2020-2025
Ospedale di Parma
2023
Dopamine is a key neurotransmitter involved in physiological processes such as motor control, motivation, reward, cognitive function, and maternal reproductive behaviors. Therefore, dysfunctions of the dopaminergic system are related to plethora human diseases. Dopamine, via different circuitries implicated compulsive behavior, habit formation, also represents player substance use disorder formation perpetuation mechanisms leading addiction. Here, we propose dopamine model not only...
Atrial Fibrillation can be considered a geriatric syndrome for its prevalence and incidence, impact on patients’ quality of life, Health Systems’ economy. The European Society Cardiology 2024 guidelines introduce recommendation maintaining vitamin K antagonist therapy over switching to direct oral anticoagulants in clinically stable elderly patients with atrial fibrillation. This article explores the implications this indication clinical context. focus will also devoted need stratification...
During aging, many physiological systems spontaneously change independent of the presence chronic diseases. The reward system is not an exception and its dysfunction generally includes a reduction in dopamine glutamate activities loss neurons ventral tegmental area (VTA). These impairments are even more pronounced older persons who have neurodegenerative diseases and/or affected by cognitive motoric frailty. All these changes may result occurrence frailty accelerated progression diseases,...
Abstract Count Neipperg (1775–1829), the morganatic husband of Maria Luigia Habsburg, Napoleon's former wife, presented with typical heart failure symptoms and died bilateral bronchopneumonia. Neipperg's case is an example conflict in medical field, which led to birth modern evidence‐based medicine (EBM), although almost 200 years ago, his presents same critical issues that more complex geriatric patients face today. First, attending physicians provided divergent opinions without reaching...
<title>Abstract</title> <bold>Purpose</bold> Frail and sarcopenic older individuals are high-risk population of cardiovascular events requiring multidomain intervention. The cross-talk between cardiac skeletal muscle mass is crucial to maintain physical independence in this specific population. aim the study was evaluate, a selected sample frail adults, influence two-year exercise program nutritional counseling (MCI group) compared lifestyle education (HALE on echocardiographic parameters...
Significant progress has been made in our understanding of the neurobiology Parkinson's disease (PD). Post-mortem studies are an important step and could help to comprehend not only progression motor symptoms, but also involvement other clinical domains, including cognition, behavior impulse control disorders (ICDs). The correlation neuropathological extension with stages remains challenging. Molecular imaging, positron emission tomography (PET) single photon computed (SPECT), allow for...