Gianluca Sambataro
- Systemic Sclerosis and Related Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inflammatory Myopathies and Dermatomyositis
- SARS-CoV-2 and COVID-19 Research
- Sarcoidosis and Beryllium Toxicity Research
- Dermatologic Treatments and Research
- COVID-19 Clinical Research Studies
- Salivary Gland Disorders and Functions
- Medical Imaging and Pathology Studies
- Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Sinusitis and nasal conditions
- Diagnosis and Treatment of Venous Diseases
- Eosinophilic Disorders and Syndromes
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Immunodeficiency and Autoimmune Disorders
- Heparin-Induced Thrombocytopenia and Thrombosis
- Reconstructive Surgery and Microvascular Techniques
- Cancer-related Molecular Pathways
- Salivary Gland Tumors Diagnosis and Treatment
- Vasculitis and related conditions
- Tracheal and airway disorders
- Peripheral Neuropathies and Disorders
- Voice and Speech Disorders
- Lung Cancer Diagnosis and Treatment
Università degli Studi di Enna Kore
2025
University of Catania
2017-2024
Ospedale Cannizzaro
2021-2024
Policlinico Universitario di Catania
2022-2023
University of Zurich
2023
National University of Malaysia
2023
King Edward Memorial Hospital and Seth G.S. Medical College
2023
Wolverhampton Hospital
2023
The Royal Wolverhampton NHS Trust
2023
Dr. Reddy's Foundation
2023
Antisynthetase syndrome (ASSD) is a rare clinical condition that characterized by the occurrence of classic triad, encompassing myositis, arthritis, and interstitial lung disease (ILD), along with specific autoantibodies are addressed to different aminoacyl tRNA synthetases (ARS). Until now, it has been unknown whether presence ARS might affect presentation, evolution, outcome ASSD. In this study, we retrospectively recorded time onset, characteristics, clustering triad findings, survival...
Digital ulcers (DUs) are a rather frequent and invalidating complication in systemic sclerosis (SSc), often showing very slow or null tendency to heal, spite of the commonly used local therapeutic procedures. Recently, stem cell therapy has emerged as new approach accelerate wound healing. In present study, we have tentatively treated long-lasting poorly responsive traditional SSc-related DUs by implantation autologous adipose tissue-derived (ATDC) fractions. Fifteen patients with SSc having...
Abstract Objective The aim of this study was to identify the main CT features that may help in distinguishing a progression interstitial lung disease (ILD) secondary SSc from COVID-19 pneumonia. Methods This multicentric included 22 international readers grouped into radiologist group (RADs) and non-radiologist (nRADs). A total 99 patients, 52 with 47 SSc-ILD, were study. Results Fibrosis inside focal ground-glass opacities (GGOs) upper lobes; fibrosis lower lobe GGOs; reticulations lobes...
Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy manage pandemic. Although none of currently approved vaccines are live-attenuated, several reports disease flares, waning protection, acute-onset syndromes emerged as short-term adverse events after...
Abstract Objectives To comprehensively compare the disease burden among patients with RA, PsA and AS using Patient-Reported Outcome Measurement Information System (PROMIS) scores to identify distinct patient clusters based on comorbidity profiles PROMIS outcomes. Methods Data from global COVID-19 Vaccination in Autoimmune Diseases (COVAD) 2 e-survey were analysed. Patients or undergoing treatment DMARDs included. (global physical health, mental fatigue 4a function short form 10a),...
The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution reducing poor clinical outcomes, vaccine hesitancy an obstacle achieving high levels uptake. This represents particular risk patients with autoimmune diseases, group already at increased hospitalization outcomes related infection. there is paucity long-term safety efficacy data in current evidence...
Abstract Objectives COVID-19 vaccines have been proven to be safe in the healthy population. However, gaps remain evidence of their safety patients with systemic autoimmune and inflammatory disorders (SAIDs). vaccination-related adverse events (AEs) SAIDs controls (HC) seven days post-vaccination were assessed COVAD study, a patient self-reported cross-sectional survey. Methods The survey was circulated early 2021 by >110 collaborators (94 countries) collect SAID details, vaccination...
COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs); however, hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors and reasons for IIMs, other AIRDs, non-rheumatic (nrAIDs) healthy controls (HCs), using data from two international Vaccination Autoimmune Diseases (COVAD) e-surveys.The first second COVAD patient self-reported e-surveys were...
The role of immunosuppression in SARS-CoV-2-related disease (COVID-19) is a matter debate. We here describe the course and outcome COVID-19 cohort patients undergoing treatment with calcineurin inhibitors. In this monocentric study, data were collected from outbreak Italy up to April 28th 2020. Patients followed at our hospital for solid organ transplantation or systemic rheumatic disorders (RMDs) on inhibitor (CNI)-based therapy. Selected referred North Italy. aim study was evaluate...
Our study assesses the diagnostic value of different features extracted from high resolution computed tomography (HRCT) images patients with idiopathic pulmonary fibrosis. These are investigated over a range HRCT lung volume measurements (in Hounsfield Units) for which no prior has yet been published. In particular, we provide comparison their at Unit (HU) thresholds, including corresponding functional tests.
Abstract Objective Flares of autoimmune rheumatic diseases (AIRDs) following COVID-19 vaccination are a particular concern in vaccine-hesitant individuals. Therefore, we investigated the incidence, predictors and patterns flares individuals living with AIRDs, using global Vaccination Autoimmune Diseases (COVAD) surveys. Methods The COVAD surveys were used to extract data on flare demographics, comorbidities, history, details for patients AIRDs. identified as patient-reported (a), increased...