Mrudula Joshi
A5022508981- SARS-CoV-2 and COVID-19 Research
- Inflammatory Myopathies and Dermatomyositis
- Peripheral Neuropathies and Disorders
- COVID-19 Clinical Research Studies
- Autoimmune and Inflammatory Disorders Research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Immunodeficiency and Autoimmune Disorders
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- Social Media in Health Education
- Rheumatoid Arthritis Research and Therapies
- Long-Term Effects of COVID-19
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vaccine Coverage and Hesitancy
- Diabetes and associated disorders
- Autoimmune Bullous Skin Diseases
- Muscle and Compartmental Disorders
- Viral Infections and Immunology Research
- Intramuscular injections and effects
- Chronic Disease Management Strategies
- T-cell and B-cell Immunology
- Dermatological and COVID-19 studies
- Microscopic Colitis
- Health Literacy and Information Accessibility
- Spondyloarthritis Studies and Treatments
B. J. Medical College & Sassoon Hospital
2021-2025
Medical College of Wisconsin
2024
Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy manage pandemic. Although none of currently approved vaccines are live-attenuated, several reports disease flares, waning protection, acute-onset syndromes emerged as short-term adverse events after...
Abstract Introduction/Aims In this study we investigated COVID‐19 vaccination–related adverse events (ADEs) 7 days postvaccination in patients with idiopathic inflammatory myopathies (IIMs) and other systemic autoimmune disorders (SAIDs). Methods Seven‐day vaccine ADEs were collected an international patient self‐reported e‐survey. Descriptive statistics obtained multivariable regression was performed. Results Ten thousand nine hundred respondents analyzed (1227 IIM cases, 4640 SAID 5033...
Abstract Objectives To comprehensively compare the disease burden among patients with RA, PsA and AS using Patient-Reported Outcome Measurement Information System (PROMIS) scores to identify distinct patient clusters based on comorbidity profiles PROMIS outcomes. Methods Data from global COVID-19 Vaccination in Autoimmune Diseases (COVAD) 2 e-survey were analysed. Patients or undergoing treatment DMARDs included. (global physical health, mental fatigue 4a function short form 10a),...
Abstract Objectives COVID-19 vaccines have been proven to be safe in the healthy population. However, gaps remain evidence of their safety patients with systemic autoimmune and inflammatory disorders (SAIDs). vaccination-related adverse events (AEs) SAIDs controls (HC) seven days post-vaccination were assessed COVAD study, a patient self-reported cross-sectional survey. Methods The survey was circulated early 2021 by >110 collaborators (94 countries) collect SAID details, vaccination...
COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs); however, hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors and reasons for IIMs, other AIRDs, non-rheumatic (nrAIDs) healthy controls (HCs), using data from two international Vaccination Autoimmune Diseases (COVAD) e-surveys.The first second COVAD patient self-reported e-surveys were...
YouTube is the second most popular search website worldwide to access health information online. This study was undertaken assess reliability and quality of about myositis on delineate attributes useful videos using standard metrics.We conducted a thorough 9 terms related myositis. The inclusion criteria were content myositis, English language acceptable audio-video quality. Duplicates advertisements excluded from analysis. Videos classified as useful, not very or misleading patient...
Abstract Objective Flares of autoimmune rheumatic diseases (AIRDs) following COVID-19 vaccination are a particular concern in vaccine-hesitant individuals. Therefore, we investigated the incidence, predictors and patterns flares individuals living with AIRDs, using global Vaccination Autoimmune Diseases (COVAD) surveys. Methods The COVAD surveys were used to extract data on flare demographics, comorbidities, history, details for patients AIRDs. identified as patient-reported (a), increased...
Abstract Objectives The COVID-19 vaccination in autoimmune diseases (COVAD) study aimed to assess short-term vaccination-related adverse events (AEs) RA patients. Methods An online self-reported questionnaire (March–December 2021) was used capture data related AEs RA, other rheumatic (AIRDs) (excluding and inflammatory myositis), non-rheumatic (nrAIDs) healthy controls (HCs). Descriptive multivariable regression analyses were performed. Results Of the 9462 complete respondents, 14.2% (n =...
Abstract Objectives Disease flares in the post–coronavirus disease 2019 (COVID-19) vaccination period represent a prominent concern, though risk factors are poorly understood. We studied these among patients with idiopathic inflammatory myopathies (IIMs) and other autoimmune rheumatic diseases (AIRDs). Methods The COVAD-1 -2 global surveys were circulated early 2021 2022, respectively, we captured demographics, comorbidities, AIRDs details, COVID-19 infection history details. Flares of IIMs...
Abstract Objectives We aimed to compare the spectrum and severity of COVID-19 vaccine breakthrough infections (BIs) among patients with IIMs, other systemic autoimmune inflammatory diseases (SAIDs), healthy controls (HCs). Methods This is a cross-sectional study data from COVAD study, self-reported online global survey that collected demographics, history, vaccination details April September 2021. Adult at least one dose were included. BIs defined as occurring > 2 weeks after any vaccine....
Abstract Objective To determine COVID-19 vaccine-related adverse events (AEs) in the seven-day post-vaccination period patients with SLE vs autoimmune rheumatic diseases (AIRDs), non-rheumatic (nrAIDs), and healthy controls (HC). Methods Data were captured through Vaccination Autoimmune Diseases (COVAD) questionnaire (March–December 2021). Multivariable regression models accounted for age, gender, ethnicity, vaccine type background treatment. Results Among 9462 complete respondents, 583...
Abstract Limited evidence on long-term COVID-19 vaccine safety in patients with idiopathic inflammatory myopathies (IIMs) continues to contribute hesitancy. We studied delayed-onset adverse events (AEs) IIMs, other systemic autoimmune and disorders (SAIDs), healthy controls (HCs), using data from the second Vaccination Autoimmune Diseases (COVAD) study. A validated self-reporting e-survey was circulated by COVAD study group (157 collaborators, 106 countries) Feb–June 2022. collected...
Idiopathic inflammatory myopathies (IIMs) confer a significant risk of disability and poor quality life, though fatigue, an important contributing factor, remains under-reported in these individuals. We aimed to compare analyze differences visual analog scale (VAS) scores (0-10 cm) for fatigue (VAS-F) patients with IIMs, non-IIM systemic autoimmune diseases (SAIDs), healthy controls (HCs). performed cross-sectional analysis the data from COVID-19 Vaccination Autoimmune Diseases (COVAD)...
Abstract Background The pandemic presented unique challenges for individuals with autoimmune and rheumatic diseases (AIRDs) due to their underlying condition, the effects of immunosuppressive treatments, increased vaccine hesitancy. Objectives COVID‐19 vaccination in (COVAD) study, a series ongoing, patient self‐reported surveys were conceived vision being tool gather perspectives on AIRDs. It involved multinational, multicenter collaborative effort amidst global lockdown. Methods Leveraging...
Abstract Background Despite the overall safety and efficacy of COVID‐19 vaccinations, rare cases systemic autoimmune diseases (SAIDs) have been reported post‐vaccination. This study used a global survey to analyze SAIDs in susceptible individuals' Methods A cross‐sectional was conducted among participants with self‐reported new‐onset using Vaccination Autoimmune Diseases (COVAD) 2 dataset—a validated, patient‐reported e‐survey—to long‐term vaccines. Baseline characteristics patients...
Notwithstanding the wealth of literature on COVID-19, studies focusing young adults with autoimmune diseases (AD) are lacking. To determine early (within 7 days) and late (after anti-SARS-CoV-2 vaccine-related adverse events (AEs), post-vaccine disease flares, COVID-19 severity breakthrough infections (B-INFs) in people rheumatic (RMDs) non-rheumatic (nr-ADs) compared to healthy controls (HC). Data were captured through international vaccination (COVAD) 1 2 questionnaires. Of 20,685 complete...
The assessment of physical function is fundamental in the management patients with idiopathic inflammatory myopathies (IIMs). We aimed to investigate IIMs compared those non-IIM autoimmune rheumatic diseases (AIRDs) utilizing Patient-Reported Outcome Measurement Information System (PROMIS) Physical Function (PF) data obtained COVAD study, an international self-reported e-survey assessing safety COVID-19 vaccines AIRDs.Demographics, AIRD diagnosis, disease activity, and PROMIS PF short...
Reactive arthritis (ReA) is an often neglected disease that received some attention during the coronavirus 2019 (COVID-19) pandemic. There evidence infection with severe acute respiratory syndrome 2 can lead to "reactive" arthritis. However, this does not follow classical definition of ReA limits organisms leading condition. Also, there no recommendation by any international society on management current Thus, a survey was conducted gather information about how modern clinicians across world...