Giovanni Orsolini
A5024251948- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Bone health and treatments
- Bone and Joint Diseases
- Bone health and osteoporosis research
- SARS-CoV-2 and COVID-19 Research
- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Bone Metabolism and Diseases
- Viral Infections and Immunology Research
- Mast cells and histamine
- Immunodeficiency and Autoimmune Disorders
- Atherosclerosis and Cardiovascular Diseases
- Monoclonal and Polyclonal Antibodies Research
- Vitamin D Research Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- COVID-19 Clinical Research Studies
- Peripheral Neuropathies and Disorders
- Autoimmune and Inflammatory Disorders Research
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- IgG4-Related and Inflammatory Diseases
University of Verona
2015-2024
Azienda Ospedaliera Universitaria Integrata Verona
2016-2024
National University of Malaysia
2023
University of Nigeria Teaching Hospital
2023
King Edward Memorial Hospital and Seth G.S. Medical College
2023
Wolverhampton Hospital
2023
The Royal Wolverhampton NHS Trust
2023
Dr. Reddy's Foundation
2023
LUPUS UK
2022-2023
Policlinico San Matteo Fondazione
2023
To develop new antiphospholipid syndrome (APS) classification criteria with high specificity for use in observational studies and trials, jointly supported by the American College of Rheumatology (ACR) EULAR. This international multidisciplinary initiative included 4 phases: 1) Phase I, generation surveys literature review; 2) II, reduction modified Delphi nominal group technique exercises; 3) III, definition, further guidance real-world patient scenarios, weighting via consensus-based...
<h3>Objective</h3> To develop new antiphospholipid syndrome (APS) classification criteria with high specificity for use in observational studies and trials, jointly supported by the American College of Rheumatology (ACR) EULAR. <h3>Methods</h3> This international multidisciplinary initiative included four phases: (1) Phase I, generation surveys literature review; (2) II, reduction modified Delphi nominal group technique exercises; (3) III, definition, further guidance real-world patient...
Objective Environmental air pollution has been associated with disruption of the immune system at a molecular level. The primary aim present study was to describe association between long-term exposure and risk developing immune-mediated conditions. Methods We conducted retrospective observational on nationwide dataset women men. Diagnoses various diseases (IMIDs) were retrieved. Data monitoring particulate matter (PM)10 PM2.5 concentrations retrieved from Italian Institute Protection...
To investigate predictors of response, remission, low disease activity, damage, and drug discontinuation in patients with systemic lupus erythematosus (SLE) who were treated belimumab.In this retrospective study a multicenter cohort SLE received intravenous belimumab, the proportion achieved treatment response according to Responder Index 4 (SRI-4) was determined, Systemic Lupus International Collaborating Clinics/American College Rheumatology Damage (SDI) used score damage yearly over...
Environmental air pollution has been linked to the pathogenesis of RA. Nevertheless, evidence linking higher concentrations pollutants with risk RA reactivations is missing. The objective present study was determine association between flares and pollution.We collected longitudinal data patients affected by daily concentration in Verona area. We designed a case-crossover study. compared exposure 30-day 60-day periods preceding an arthritic flare referent low-disease activity visit.The...
Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy manage pandemic. Although none of currently approved vaccines are live-attenuated, several reports disease flares, waning protection, acute-onset syndromes emerged as short-term adverse events after...
Abstract Objectives To comprehensively compare the disease burden among patients with RA, PsA and AS using Patient-Reported Outcome Measurement Information System (PROMIS) scores to identify distinct patient clusters based on comorbidity profiles PROMIS outcomes. Methods Data from global COVID-19 Vaccination in Autoimmune Diseases (COVAD) 2 e-survey were analysed. Patients or undergoing treatment DMARDs included. (global physical health, mental fatigue 4a function short form 10a),...
The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution reducing poor clinical outcomes, vaccine hesitancy an obstacle achieving high levels uptake. This represents particular risk patients with autoimmune diseases, group already at increased hospitalization outcomes related infection. there is paucity long-term safety efficacy data in current evidence...
COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs); however, hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors and reasons for IIMs, other AIRDs, non-rheumatic (nrAIDs) healthy controls (HCs), using data from two international Vaccination Autoimmune Diseases (COVAD) e-surveys.The first second COVAD patient self-reported e-surveys were...
Long-term environmental air pollution exposure was associated with osteoporosis' risk in a cohort of women at high fracture. Cortical sites seemed to be more susceptible the exposure's effect.Environmental has been disruption bone health molecular level. Particulate matter (PM) can simultaneously stimulate resorption and halt formation. The primary aim present study is describe association between long-term PM osteoporosis large fracture.Clinical, demographic, densitometric data were...
Abstract Objectives COVID-19 vaccines have been proven to be safe in the healthy population. However, gaps remain evidence of their safety patients with systemic autoimmune and inflammatory disorders (SAIDs). vaccination-related adverse events (AEs) SAIDs controls (HC) seven days post-vaccination were assessed COVAD study, a patient self-reported cross-sectional survey. Methods The survey was circulated early 2021 by &gt;110 collaborators (94 countries) collect SAID details, vaccination...
Abstract Objective Flares of autoimmune rheumatic diseases (AIRDs) following COVID-19 vaccination are a particular concern in vaccine-hesitant individuals. Therefore, we investigated the incidence, predictors and patterns flares individuals living with AIRDs, using global Vaccination Autoimmune Diseases (COVAD) surveys. Methods The COVAD surveys were used to extract data on flare demographics, comorbidities, history, details for patients AIRDs. identified as patient-reported (a), increased...
Abstract Objectives To investigate health-related quality of life in patients with idiopathic inflammatory myopathies (IIMs) compared those non-IIM autoimmune rheumatic diseases (AIRDs), non-rheumatic (nrAIDs) and without (controls) using Patient-Reported Outcome Measurement Information System (PROMIS) instrument data obtained from the second COVID-19 vaccination disease (COVAD-2) e-survey database. Methods Demographics, diagnosis, comorbidities, activity, treatments PROMIS were analysed....
Abstract Objectives The COVID-19 vaccination in autoimmune diseases (COVAD) study aimed to assess short-term vaccination-related adverse events (AEs) RA patients. Methods An online self-reported questionnaire (March–December 2021) was used capture data related AEs RA, other rheumatic (AIRDs) (excluding and inflammatory myositis), non-rheumatic (nrAIDs) healthy controls (HCs). Descriptive multivariable regression analyses were performed. Results Of the 9462 complete respondents, 14.2% (n =...