A5076480220- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Systemic Sclerosis and Related Diseases
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Medical Imaging and Pathology Studies
- Asthma and respiratory diseases
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
- Inflammatory Myopathies and Dermatomyositis
- COVID-19 Clinical Research Studies
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Mycobacterium research and diagnosis
- Bone health and treatments
- Salivary Gland Disorders and Functions
- Pneumonia and Respiratory Infections
- Eosinophilic Disorders and Syndromes
- Neonatal Respiratory Health Research
- Diagnosis and treatment of tuberculosis
- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Inhalation and Respiratory Drug Delivery
Azienda Ospedaliera San Gerardo
2019-2025
University of Milano-Bicocca
2019-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
University of Modena and Reggio Emilia
2013-2022
Metropolitan University
2021
Azienda Ospedaliero-Universitaria di Modena
2010-2020
Ospedale Santa Maria
2020
Azienda Ospedaliera San Giovanni Addolorata
2012
Thorax Foundation
2008
University of Parma
2006
Chronic obstructive pulmonary disease (COPD) is defined by fixed airflow limitation associated with an abnormal and systemic inflammatory response of the lungs to cigarette smoke. The inflammation induced smoking may also cause chronic heart failure, metabolic syndrome other diseases, which contribute clinical manifestations natural history COPD. Thus COPD can no longer be considered a only lungs, as it often wide variety consequences. A better understanding origin consequences inflammation,...
Chronic obstructive pulmonary disease (COPD) is often associated with other chronic diseases. These patients are admitted to hospital based rehabilitation programmes.To determine the prevalence of comorbidities in COPD undergoing and assess their influence on outcome.Observational retrospective cohort study.A single centre.2962 inpatients outpatients (73% male, aged 71 (SD 8) years, forced expiratory volume 1 s (FEV(1)) 49.3 14.8)% predicted), graded 0, or >/=2 according comorbidity...
Long-term pulmonary sequelae following hospitalization for SARS-CoV-2 pneumonia is largely unclear. The aim of this study was to identify and characterise caused by at 12-month from discharge.
Abstract Objective The aim of this study was to identify the main CT features that may help in distinguishing a progression interstitial lung disease (ILD) secondary SSc from COVID-19 pneumonia. Methods This multicentric included 22 international readers grouped into radiologist group (RADs) and non-radiologist (nRADs). A total 99 patients, 52 with 47 SSc-ILD, were study. Results Fibrosis inside focal ground-glass opacities (GGOs) upper lobes; fibrosis lower lobe GGOs; reticulations lobes...
Rationale Pulse glucocorticoid therapy is used in hyperinflammation related to coronavirus disease 2019 (COVID-19). We evaluated the efficacy and safety of pulse intravenous methylprednisolone addition standard treatment COVID-19 pneumonia. Methods In this multicentre, randomised, double-blind, placebo-controlled trial, 304 hospitalised patients with pneumonia were randomised receive 1 g intravenously for three consecutive days or placebo dexamethasone. The primary outcome was duration...
Die gewöhnliche interstitielle Pneumonie (UIP) ist durch die fortschreitende Lungenparenchymveränderung gekennzeichnet, bei verschiedenen rheumatischen Autoimmunerkrankungen (ARD), einschließlich rheumatoider Arthritis und Bindegewebserkrankungen, beobachtet werden kann. Aus diagnostischer Sicht kann ein UIP-Muster im Zusammenhang mit ARD bildgebende pathologische Merkmale aufweisen, denen es von dem Muster der idiopathischen Lungenfibrose (IPF) unterschieden kann, etwa das...
Abstract Background Increased airway epithelial proliferation is frequently observed in smokers. To elucidate the molecular mechanisms leading to these changes, we studied effect of cigarette smoke condensate (CSC) on cell proliferation, wound closure and mitogen activated protein kinase (MAPK) activation. We also whether modulation intracellular glutathione/thiol levels could attenuate CSC-induced proliferation. Methods Cells bronchial line NCI-H292 subcultures primary cells were used for...
Recent evidences show that Pulmonary Rehabilitation (PR) is effective in patients with Interstitial Lung Disease (ILD). It still unclear whether disease severity and/or etiology might impact on the reported benefits. We designed this prospective study 1) to confirm efficacy of rehabilitation a population ILDs and 2) investigate baseline exercise capacity, or ILD affect outcomes. Forty-one (IPF 63%, age 66.9 ± 11 ys) were enrolled standard PR course two centers. function, incremental...