A5054709938- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Patient Dignity and Privacy
- Childhood Cancer Survivors' Quality of Life
- Patient-Provider Communication in Healthcare
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Family and Patient Care in Intensive Care Units
- Geriatric Care and Nursing Homes
- Long-Term Effects of COVID-19
- Ethics in medical practice
- Breast Cancer Treatment Studies
- Grief, Bereavement, and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Pain Management and Opioid Use
- Gastroesophageal reflux and treatments
- Family Support in Illness
- Advances in Oncology and Radiotherapy
- Breast Lesions and Carcinomas
- Esophageal and GI Pathology
- COVID-19 and healthcare impacts
- Palliative and Oncologic Care
- Frailty in Older Adults
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2025
Fondazione IRCCS Istituto Nazionale dei Tumori
2022-2024
Instituto Nazionale Tumori Regina Elena
2024
King's College London
2002-2024
Cicely Saunders International
2024
Azienda Sanitaria Unità Locale di Reggio Emilia
2018-2022
Collaborative Group (United States)
2022
Azienda Unità Sanitaria Locale Della Romagna
2019
Agostino Gemelli University Polyclinic
2019
Ospedale Santa Maria
2014-2017
The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of people worldwide. Tocilizumab has shown promising results in retrospective studies patients with COVID-19 pneumonia a good safety profile.To evaluate the effect early tocilizumab administration vs standard therapy preventing clinical worsening hospitalized pneumonia.Prospective, open-label, randomized trial that between March 31 and June 11, 2020, to receive or care 24 hospitals Italy. Cases were confirmed by...
Background: Palliative care is an important component of health in pandemics, contributing to symptom control, psychological support, and supporting triage complex decision making. Aim: To examine preparedness for, impact of, the COVID-19 pandemic on hospices Italy inform response other countries. Design: Cross-sectional telephone survey, March 2020. Setting: Italian hospices, purposively sampled according regional prevalence categorised as high (>25), medium (15–25) low (<15) cases...
To describe actual and preferred place of death Italian cancer patients to analyse the preferences met regarding death.Mortality follow back survey 2000 deaths, identified with a two stage probability sample representative whole country. Information on patients' experience was gathered from non-professional caregiver an interview. A section interview covered information patients.30 local health districts randomly selected after stratification in four geographical areas.1900 (95.0%)...
The Hospital Anxiety and Depression Scale (HADS) is a widely used self-report measure to assess emotional distress in clinical populations. As highlighted recent review studies, the latent structure of HADS still an issue. aim this study was analyze factorial large community sample Italy, test invariance best fitting model across age gender groups. Data analyses were carried out on 1.599 participants proportionally stratified according Italian census population pyramid. Participants aged 18...
Abstract Background Tocilizumab blocks pro-inflammatory activity of interleukin-6 (IL-6), involved in pathogenesis pneumonia the most frequent cause death COVID-19 patients. Methods A multicenter, single-arm, hypothesis-driven trial was planned, according to a phase 2 design, study effect tocilizumab on lethality rates at 14 and 30 days (co-primary endpoints, priori expected being 20 35%, respectively). further prospective cohort patients, consecutively enrolled after first accomplished,...
Rationale Pulse glucocorticoid therapy is used in hyperinflammation related to coronavirus disease 2019 (COVID-19). We evaluated the efficacy and safety of pulse intravenous methylprednisolone addition standard treatment COVID-19 pneumonia. Methods In this multicentre, randomised, double-blind, placebo-controlled trial, 304 hospitalised patients with pneumonia were randomised receive 1 g intravenously for three consecutive days or placebo dexamethasone. The primary outcome was duration...
This population-based study of all cancer deaths (n = 12,343) occurring in Genoa, Italy, from 1986 to 1990 investigated the relation between place death and age, sex, marital status, education, site provision palliative home care (PHC). The proportion significantly increased 27.9% (1986) 33.0% (1990) was twice as frequent among PHC users (60.8%) than nonusers (29.3%). number patients dying who received 41 (1.6% deaths) 191 (8.0% deaths). users, when compared were younger, more frequently...
Although erythropoietin (EPO) is known to be useful in treating chemotherapy-induced anemia, few data are available on its potential preventive role. The aim of this study was evaluate the ability EPO preventing development clinically significant anemia patients treated with chemotherapy.Sixty-two early-stage breast cancer undergoing accelerated adjuvant chemotherapy were randomized receive 150 U/kg three times a week or no additional treatment. Chemotherapy consisted six cycles...
Abstract Background Patients with solid or hematological tumors neurological and immune-inflammatory disorders are potentially fragile subjects at increased risk of experiencing severe coronavirus disease 2019 an inadequate response to acute respiratory syndrome 2 (SARS-CoV-2) vaccination. Methods We designed a prospective Italian multicenter study assess humoral T-cell responses SARS-CoV-2 vaccination in patients (n = 378) (ST), malignancies (HM), (ND), immunorheumatological diseases (ID)....