A5004970438- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Drug-Induced Ocular Toxicity
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Heparin-Induced Thrombocytopenia and Thrombosis
- Coronary Interventions and Diagnostics
- Renal and Vascular Pathologies
- Aortic Disease and Treatment Approaches
- interferon and immune responses
- Cardiac Imaging and Diagnostics
- Ophthalmology and Eye Disorders
- Vascular anomalies and interventions
- Central Venous Catheters and Hemodialysis
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
University of Liège
2023-2025
Istituto Clinico Sant'Ambrogio
2023-2025
University of Milan
2022-2025
IRCCS Policlinico San Donato
2019-2024
University of Pisa
2022
Abstract Background Tocilizumab blocks pro-inflammatory activity of interleukin-6 (IL-6), involved in pathogenesis pneumonia the most frequent cause death COVID-19 patients. Methods A multicenter, single-arm, hypothesis-driven trial was planned, according to a phase 2 design, study effect tocilizumab on lethality rates at 14 and 30 days (co-primary endpoints, priori expected being 20 35%, respectively). further prospective cohort patients, consecutively enrolled after first accomplished,...
BackgroundHydroxychloroquine (HCQ) and azithromycin (AZT) have been proposed for COVID-19 treatment. Data available in the literature reported a potential increased risk of fatal arrhythmias under these therapies. The aim this study was to assess effects drugs on QT interval outcome population.MethodA total 112 consecutive patients were included analysis divided 3 groups according receiving therapeutic regimens: 19 (17%) Group 1 (no treatment), 40 (36%) 2 (HCQ only), 53 (47%)...
Recently, a staging system using 4 grades has been proposed to quantify the extent of cardiac damage associated with aortic stenosis (AS), namely AS-related (ASCDS). ASCDS is independently all-cause mortality and important clinical outcomes. To evaluate whether it might be occurrence conduction disorders after TAVI, total 119 symptomatic patients severe AS who underwent TAVI were categorized according ASCDS: group 1 (13.5%): no or LV damage; 2 (58.8%): left atrial/mitral valve damage, atrial...
Abstract Aims In acute heart failure (AHF), the consequences of impaired left atrial (LA) mechanics are not well understood. We aimed to define clinical trajectory LA by strain (LAS) analysis. Methods and results Eighty-five consecutive AHF patients with reduced, mildly preserved ventricular ejection fraction (LVEF) were enrolled in LAS-AHF trial underwent analysis speckle tracking echocardiography. Seventy-seven followed-up (FU) at 6 12 months. At hospital admission, discharge, months...
Key Points Surgical AVF ligation in KTRs is associated with a significant increase diastolic BP while systolic remains stable. closure leads to an improvement of LV and LA morphology decrease serum NT-proBNP levels. There no effect on kidney allograft function: The eGFR stable over time. Background Kidney transplantation considered as the best replacement therapy, arteriovenous fistula (AVF) preferred vascular access for hemodialysis. systematic functioning transplant recipients (KTRs)...
Although staging of the extent aortic stenosis (AS)-related cardiac damages is usually performed via echocardiography, this technique has considerable limitations in assessing pulmonary artery and right chamber pressures. The present hypothesis-generating study sought to explore efficacy a system damage based on echocardiographic invasive [right heart catheterization (RHC)] hemodynamic parameters patients undergoing transcatheter valve implantation (TAVI). We studied 90 symptomatic with...
Abstract Aims The prognostic impact of flow trajectories according to stroke volume index (SVi) and transvalvular rate (FR) in patients with severe aortic stenosis (AS) undergoing transcatheter valve replacement (TAVR) remains poorly assessed. We evaluated compared SVi FR prior after TAVR for AS. Methods results Patients were categorized (<35 mL/m2) (<200 mL/s). association pre- post-TAVR all-cause mortality up 3 years was assessed multivariable Cox regression models. Among 980...
Since its first implementation, minimally invasive cardiac surgery has become more and popular among surgeons. By avoiding a complete opening of the sternum, this is traditionally associated with faster recovery, less surgical pain postoperative bleeding transfusions. With growing popularity, need for specifically designed instrumentation evident. 2008, detachable-branch Glauber clamp (Cardiovision-Trytech, Tokyo, Japan) been used to facilitate aortic cross-clamp during surgery, optimize...
To evaluate whether the extent of cardiac damage in severe aortic stenosis (AS) might be associated with occurrence conduction system disorders after TAVI. A total 153 symptomatic patients AS who had a TAVI were categorized before procedure according to damage: stage 1 (13.5%): no or LV damage; 2 (58.8%): left atrial/mitral valve damage, atrial fibrillation (AF); 3 (27.7%): low-flow state, pulmonary vasculature/tricuspid valve/RV damage. After TAVI, 34% exhibited LBBB and 10% high-degree...
Objective: Minimally invasive surgery determines shorter postoperative hospital length of stay (LOS) even in cardiac surgery. Potential preoperative factors affecting LOS are still not known minimally heart valve (MIVS). We aimed to identify variables influencing prolonged MIVS. Methods: reviewed 189 patients who underwent MIVS via minithoracotomy at our institution. Prolonged was defined as more than 7 days. Poisson and logistic regression were used screen the predictors. Results: The mean...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)