A5074196528- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Kidney Injury Research
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Anesthesia and Pain Management
- Renal function and acid-base balance
- Palliative Care and End-of-Life Issues
- Airway Management and Intubation Techniques
- Ultrasound in Clinical Applications
- Nausea and vomiting management
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- Dialysis and Renal Disease Management
- Radiation Dose and Imaging
- Non-Invasive Vital Sign Monitoring
- Family and Patient Care in Intensive Care Units
- Nutrition and Health in Aging
- Spine and Intervertebral Disc Pathology
- Abdominal Surgery and Complications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Muscle and Compartmental Disorders
University of Milan
2021-2024
IRCCS Policlinico San Donato
2011-2024
Azienda Sanitaria Unità Locale di Reggio Emilia
2020-2021
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2021
Istituto Clinico Sant'Ambrogio
2007
University of Trieste
1999-2003
Fondazione IRCCS Istituto Nazionale dei Tumori
2002
Fondazione IRCCS Istituto Neurologico Carlo Besta
2001
Ospedale di Cattinara
1999
Few observations exist with respect to the pro-coagulant profile of patients COVID-19 acute respiratory distress syndrome (ARDS). Reports thromboembolic complications are scarce but suggestive for a clinical relevance problem.Prospective observational study aimed characterize coagulation ARDS standard and viscoelastic tests evaluate their changes after establishment an aggressive thromboprophylaxis.Sixteen received complete at admission in intensive care unit. Ten were followed subsequent 7...
Abstract Background Tocilizumab blocks pro-inflammatory activity of interleukin-6 (IL-6), involved in pathogenesis pneumonia the most frequent cause death COVID-19 patients. Methods A multicenter, single-arm, hypothesis-driven trial was planned, according to a phase 2 design, study effect tocilizumab on lethality rates at 14 and 30 days (co-primary endpoints, priori expected being 20 35%, respectively). further prospective cohort patients, consecutively enrolled after first accomplished,...
Abstract Background Systemic inflammation in COVID-19 often leads to multiple organ failure, including acute kidney injury (AKI). Renal replacement therapy (RRT) combination with sequential extracorporeal blood purification therapies (EBP) might support renal function, attenuate systemic inflammation, and prevent or mitigate dysfunctions COVID-19. Aim Describe overtime variations of clinical biochemical features critically ill patients treated EBP a hemodiafilter characterized by enhanced...
Abstract Background During the first coronavirus disease 2019 (COVID-19) pandemic wave, an unprecedented number of patients with respiratory failure due to a new, highly contagious virus needed hospitalization and intensive care unit (ICU) admission. The aim present study was describe communication visiting policies Italian units (ICUs) during COVID-19 wave national lockdown compare these data prepandemic conditions. Methods A web-based survey conducted among 290 hospitals. Each ICU (active...
The outbreak of coronavirus disease 2019 (COVID-19) has caused significant delays in oncological care worldwide due to restriction elective surgery and intensive unit capacity. It been hypothesized that COVID-free hubs can provide safer cancer compared COVID hospitals. primary aim the present study was analyze outcomes minimally invasive esophagectomy for performed both hospital settings by same surgical staff.All esophagectomies during pandemic a single team were reviewed data with control...
<b><i>Background:</i></b> Critically ill patients with acute respiratory failure frequently present concomitant lung and kidney injury, within a multiorgan condition due to local systemic mediators. To face this issue, extracorporeal carbon dioxide removal (ECCO<sub>2</sub>R) systems have been integrated into continuous renal replacement therapy (CRRT) platforms provide combined organ support, efficient clearance of CO<sub>2</sub> very low...
<b><i>Introduction:</i></b> Membrane fouling is a significant complication potentially reducing clinical effects of extracorporeal blood purification (EBP) in critically ill septic patients with acute kidney injury. Although fascinating, the effect heparin coating preventing membrane currently unknown. This multicenter prospective study aims to preliminary describe incidence, associated factors, and consequences premature circuit clotting cohort adult treated EBP...
Summary Background Systemic sclerosis (SSc) is a rare autoimmune and multiorgan disorder. Hallmarks of the disease include inflammation, endothelial dysfunction, dysregulation fibroblasts leading to fibrosis skin internal organs. The esophagus often involved, with up 80% patients developing gastroesophageal reflux (GERD). Reflux can be associated hiatal hernia several complications such as erosive esophagitis, peptic stricture, Barrett’s esophagus, aspiration pneumonia, chronic...
Background:The importance of knowing the blood volume, in critically ill patients, collides with difficulty to have its direct measure through a safe and economic method.Hydroxyethyl starch (HES) was introduced by Tschaikowsky as useful marker for dilution method, calculating HES concentration (HESC) solution inducing an in-vitro hydrolysis molecules into glucose monomers dosing consequent increase level (Δ GLUCOSE).Objective: This study develops simple cheap laboratory technique which uses...
During citrate-based Continuous Renal Replacement Therapy (CRRT), an infusion of calcium is necessary to replace the lost in effluent. The replacement takes place through a central venous catheter (CVC) that primed with saline solution. Thus, we hypothesized potential systemic anticoagulation caused by unchelated citrate reaching patient at start CRRT because 0.42 ml line dead space. In this pilot study, two subpopulations 7 patients who underwent Veno-Venous Hemodiafiltration (150 ml/min...