Giacomo Bellani
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Mechanical Circulatory Support Devices
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Long-Term Effects of COVID-19
- Family and Patient Care in Intensive Care Units
- Nosocomial Infections in ICU
- Pleural and Pulmonary Diseases
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Thermal Regulation in Medicine
- Ultrasound in Clinical Applications
- Pericarditis and Cardiac Tamponade
- Pneumothorax, Barotrauma, Emphysema
- Trauma Management and Diagnosis
- Pulmonary Hypertension Research and Treatments
- Biomarkers in Disease Mechanisms
- Restraint-Related Deaths
- Cardiac, Anesthesia and Surgical Outcomes
Ospedale Santa Chiara
2023-2025
University of Trento
2023-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
University of Milano-Bicocca
2015-2024
Azienda Ospedaliera San Gerardo
2015-2024
Vall d'Hebron Hospital Universitari
2024
Provincia Autonoma di Trento
2024
ASST Melegnano e della Martesana
2020-2023
Institution of Engineering and Technology
2023
American Heart Association
2023
<h3>Importance</h3> Many patients with coronavirus disease 2019 (COVID-19) are critically ill and require care in the intensive unit (ICU). <h3>Objective</h3> To evaluate independent risk factors associated mortality of COVID-19 requiring treatment ICUs Lombardy region Italy. <h3>Design, Setting, Participants</h3> This retrospective, observational cohort study included 3988 consecutive laboratory-confirmed referred for ICU admission to coordinating center (Fondazione IRCCS [Istituto di...
Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS). The evidence supporting NIV use ARDS remains relatively sparse.To determine whether, during NIV, the categorization of severity based on PaO2/FiO2 Berlin criteria useful.The LUNG SAFE (Large Observational Study to Understand Global Impact Severe Acute Respiratory Failure) study described management ARDS. This substudy examines current practice ARDS, utility ratio classifying...
High-flow nasal cannula (HFNC) improves the clinical outcomes of nonintubated patients with acute hypoxemic respiratory failure (AHRF).To assess effects HFNC on gas exchange, inspiratory effort, minute ventilation, end-expiratory lung volume, dynamic compliance, and ventilation homogeneity in AHRF.This was a prospective randomized crossover study AHRF PaO2/setFiO2 less than or equal to 300 mm Hg admitted intensive care unit. We randomly applied set at 40 L/min compared standard nonocclusive...
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) European Society Intensive Care Medicine (ESICM). scope this CPG limited adult patients and non-pharmacological respiratory support strategies across different aspects acute distress syndrome (ARDS), including ARDS due coronavirus disease 2019 (COVID-19). These were formulated by an international panel experts, one methodologist patients’ representatives on behalf ESICM. review was conducted in compliance...
<h3>Importance</h3> Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information available on adverse peri-intubation events. <h3>Objective</h3> To evaluate incidence nature events to assess current practice <h3>Design, Setting, Participants</h3> The International Observational Study Understand Impact Best Practices Airway Management Critically Ill Patients (INTUBE) study was an international, multicenter, prospective...
Mechanical ventilation can cause acute diaphragm atrophy and injury, this is associated with poor clinical outcomes. Although the importance impact of lung-protective widely appreciated well established, concept diaphragm-protective has recently emerged as a potential complementary therapeutic strategy. This Perspective, developed from discussions at meeting international experts convened by PLUG (the Pleural Pressure Working Group) European Society Intensive Care Medicine, outlines...
Rationale: Treatment with noninvasive ventilation (NIV) in coronavirus disease (COVID-19) is frequent. Shortage of intensive care unit (ICU) beds led clinicians to deliver NIV also outside ICUs. Data about the use COVID-19 limited.Objectives: To describe prevalence and clinical characteristics patients treated investigate factors associated failure (need for intubation or death).Methods: In this prospective, single-day observational study, we enrolled adult who were ICU from 31 hospitals...
This document updates previously published Clinical Practice Guidelines for the management of patients with acute respiratory distress syndrome (ARDS), incorporating new evidence addressing use corticosteroids, venovenous extracorporeal membrane oxygenation, neuromuscular blocking agents, and positive end-expiratory pressure (PEEP).
Rationale: Cardiovascular instability/collapse is a common peri-intubation event in patients who are critically ill. Objectives: To identify potentially modifiable variables associated with cardiovascular (i.e., systolic arterial pressure <65 mm Hg [once] or <90 for >30 minutes; new/increased vasopressor requirement; fluid bolus >15 ml/kg, cardiac arrest). Methods: INTUBE (International Observational Study to Understand the Impact and Best Practices of Airway Management In Critically Ill...
Defining lung recruitability is needed for safe positive end-expiratory pressure (PEEP) selection in mechanically ventilated patients. However, there no simple bedside method including both assessment of and risks overdistension as well personalized PEEP titration.
Rationale: Hypoxemia during mechanical ventilation might be worsened by expiratory muscle activity, which reduces end-expiratory lung volume through collapse. A proposed mechanism of benefit from neuromuscular blockade (NMBA) in acute respiratory distress syndrome (ARDS) is abolition efforts. This may contribute to restoration volumes. The prevalence this phenomenon, however, unknown. Objectives: To investigate the incidence and amount impedance (EELI) increase after NMBA, clinical factors...
Studies on head injury-induced pituitary dysfunction are limited in number and conflicting results have been reported.To further clarify this issue, 29 consecutive patients (24 males), with severe (n = 21) or moderate 8) trauma, having a mean age of 37 ± 17 years were investigated the immediate post-trauma period.All required mechanical ventilatory support for 8-55 days enrolled study within few before ICU discharge.Basal hormonal assessment included measurement cortisol, corticotropin, free...
During acute lung injury (ALI), mechanical ventilation can aggravate inflammation by promoting alveolar distension and cyclic recruitment-derecruitment. As an estimate of the intensity inflammation, metabolic activity be measured positron emission tomography imaging [(18)F]fluoro-2-deoxy-D-glucose.To assess relationship between gas volume changes induced tidal pulmonary in patients with ALI.In 13 mechanically ventilated ALI relatively high positive end-expiratory pressure, we performed a...