- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Inhalation and Respiratory Drug Delivery
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infection Control and Ventilation
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Asthma and respiratory diseases
- Lung Cancer Diagnosis and Treatment
- Thermal Regulation in Medicine
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Breast Implant and Reconstruction
- Neuroscience and Neuropharmacology Research
- Lung Cancer Treatments and Mutations
- Pneumothorax, Barotrauma, Emphysema
- Venous Thromboembolism Diagnosis and Management
- Anesthesia and Sedative Agents
- Gastric Cancer Management and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Pleural and Pulmonary Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Family and Patient Care in Intensive Care Units
Deyang Stomatological Hospital
2025
First Affiliated Hospital of Henan University
2019-2025
Rush University
2018-2025
Beijing Chao-Yang Hospital
2015-2025
Capital Medical University
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2025
Guang’anmen Hospital
2017-2025
Yale University
2025
Peking University
2007-2025
Peking University Cancer Hospital
2009-2025
Defining lung recruitability is needed for safe positive end-expiratory pressure (PEEP) selection in mechanically ventilated patients. However, there no simple bedside method including both assessment of and risks overdistension as well personalized PEEP titration.
Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking climbing stairs. Piezo2 has been implicated the development of but mechanisms by this occurs remain poorly understood, including role nociceptors. Here we show that nociceptor-specific conditional knock-out mice were protected from sensitization inflammatory joint pain female mice, male well both knee swelling repeated intra-articular injection...
The combination of low-cost sensors, commodity computing, and the Internet is enabling a new era data-intensive science. dramatic increase in this data availability has created challenge for scientists: how to process data. Scientists today are envisioning scientific computations on large scale but having difficulty designing software architectures accommodate volume often heterogeneous inconsistent In paper, we introduce particular instance challenge, present our design implementation MODIS...
Atherosclerosis is a multifaceted inflammatory disease involving cells in the vascular wall (eg, endothelial [ECs]), as well circulating and resident immunogenic monocytes/macrophages). Acting ligand for liver X receptor (LXR), but an inhibitor of SREBP2 (sterol regulatory element-binding protein 2), 25-hydroxycholesterol, its catalyzing enzyme cholesterol-25-hydroxylase (Ch25h) are important regulating cellular status cholesterol biosynthesis both ECs monocytes/macrophages.Bioinformatic...
Abstract Background Awake prone positioning (APP) improves oxygenation in coronavirus disease (COVID-19) patients and, when successful, may decrease the risk of intubation. However, factors associated with APP success remain unknown. In this secondary analysis, we aimed to assess whether can reduce intubation rate COVID-19 and focus on success. Methods multicenter randomized controlled trial, conducted three high-acuity units, randomly assigned COVID-19-induced acute hypoxemic respiratory...
<h3>Importance</h3> Several respiratory support techniques are available to minimize the use of invasive mechanical ventilation (IMV) in preterm neonates. It is unknown whether noninvasive high-frequency oscillatory (NHFOV) more efficacious than nasal continuous positive airway pressure (NCPAP) or intermittent (NIPPV) neonates after their first extubation. <h3>Objective</h3> To test hypothesis that NHFOV NCPAP NIPPV reducing IMV extubation and until neonatal intensive care unit discharge...
Pneumoconiosis refers to a class of serious diseases threatening the health workers exposed coal or silicosis dust. However, burden pneumoconiosis is unavailable in China.Incident cases, deaths, and disability-adjusted life years (DALYs) from its subtypes China were estimated Global Burden Disease Study 2019 using Bayesian meta-regression method. The trend was analyzed percentage change annualized rate (ARC) during period 1990-2019. relationship between subnational socio-demographic index...
2D nanodendrites (NDs) and nanosheets (NSs) have been regarded as efficient nanocatalysts for enhancing the electrocatalytic performance due to their low coordinated sites abundant centers. Nevertheless, it remains challenging construct advanced NDs NSs in a single reaction system. Herein, by tuning volume ratios of mixed solvents, reduction diffusion rate Sn2+ on Pd template was rationally controlled prepare PdSn NSs. Ascribed open nanostructure, high specific surface area, robust...
Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal neoplasms with intermediate biological potential and characterized by spindle-shaped cells significant inflammatory infiltrates. This case report describes a 24-year-old male diabetes who was admitted to the hospital for over three days of vomiting abdominal pain initially diagnosed diabetic ketoacidosis. Upon admission, an CT scan revealed large cystic-solid mass in cavity multiple nodules mesentery, omentum, peritoneum,...
Objective Apple consumption has a positive effect on human health. Some studies have shown that an appropriate amount of apple intake can reduce the incidence hypertension. However, few investigated whether eating different forms apples same benefits as whole apples. This study is aimed to evaluate all-cause mortality in patients with Methods The included 2,368 All participants were followed up for at least 10 years. Cox regression model was constructed analyze correlation between apple,...
Importance The impact of awake prone positioning (APP) on clinical outcomes in patients with COVID-19 and acute hypoxemic respiratory failure (AHRF) remains uncertain. Objective To assess the association APP improved among AHRF, to identify potential effect modifiers. Data Sources PubMed, Embase, Cochrane Library, ClinicalTrials.gov were searched through August 1, 2024. Study Selection Randomized trials (RCTs) examining adults AHRF that reported intubation rate or mortality included....
Abstract High flow nasal cannula (HFNC) has been shown to improve extubation outcomes in patients with hypoxemia, but the role of HFNC weaning chronic obstructive pulmonary disease (COPD) hypercapnia from invasive ventilation is unclear. We compared effects noninvasive (NIV) on postextubation vital signs and arterial blood gases (ABGs) among COPD. Other included comfort scores, need for bronchoscopy, use medications, chest physiotherapy. Forty‐two COPD who had persistent at were assigned...
Awake prone positioning (APP) is widely used in the management of patients with coronavirus disease (COVID-19). The primary objective this study was to compare outcome COVID-19 who received early versus late APP.Post hoc analysis data collected for a randomized controlled trial (ClinicalTrials.gov NCT04325906). Adult acute hypoxemic respiratory failure secondary APP at least one hour were included. Early defined as initiated within 24 h high-flow nasal cannula (HFNC) start. Primary outcomes...
Clinical practice of aerosol delivery in conjunction with respiratory support devices for critically ill adult patients remains a topic controversy due to the complexity clinical scenarios and limited evidence. To reach consensus guiding receiving (invasive noninvasive) identifying areas future research. A modified Delphi method was adopted achieve on technical aspects various forms support, including mechanical ventilation, noninvasive high-flow nasal cannula. thorough search review...