A5034856974- Sports injuries and prevention
- Respiratory Support and Mechanisms
- Adipose Tissue and Metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ultrasound in Clinical Applications
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Knee injuries and reconstruction techniques
- Experimental Learning in Engineering
- Various Chemistry Research Topics
- Family and Patient Care in Intensive Care Units
- Drug-Induced Hepatotoxicity and Protection
- Fibroblast Growth Factor Research
- Cardiovascular Disease and Adiposity
- Electrowetting and Microfluidic Technologies
- Foot and Ankle Surgery
- Pneumothorax, Barotrauma, Emphysema
- Sarcoidosis and Beryllium Toxicity Research
- Respiratory and Cough-Related Research
- COVID-19 and healthcare impacts
- Radiology practices and education
- Airway Management and Intubation Techniques
- GDF15 and Related Biomarkers
- Orthopedic Infections and Treatments
META Group
2025
Analysis Group (United States)
2025
Western New Mexico University
2023
University of Iowa Hospitals and Clinics
2019-2022
University of Iowa
2019-2021
University of Missouri
2013-2016
Harry S. Truman Memorial Veterans' Hospital
2013-2016
Importance The impact of awake prone positioning (APP) on clinical outcomes in patients with COVID-19 and acute hypoxemic respiratory failure (AHRF) remains uncertain. Objective To assess the association APP improved among AHRF, to identify potential effect modifiers. Data Sources PubMed, Embase, Cochrane Library, ClinicalTrials.gov were searched through August 1, 2024. Study Selection Randomized trials (RCTs) examining adults AHRF that reported intubation rate or mortality included....
Diabetes mellitus (DM) is an independent risk factor for heart disease and its underlying mechanisms are unclear. Increased expression of diabetic marker miR-29 family miRNAs (miR-29a, b c) that suppress the pro-survival protein Myeloid Cell Leukemia 1(MCL-1) reported in pancreatic β-cells Type 1 DM. Whether up-regulation suppression MCL-1 (dysregulation miR-29-MCL-1 axis) occurs not known. This study tested hypothesis insulin regulates cardiac axis dysregulation correlates with DM...
Spirometry results can yield a diagnosis of normal air flow, flow obstruction, or preserved ratio impaired spirometry (PRISm), defined as reduced FEV1 FVC in the setting FEV1/FVC. Previous studies have estimated prevalence PRISm to be 7-12%. Our objective was examine database and identify factors associated with PRISm.We performed retrospective analysis 21,870 spirometries; 1,616 were excluded because missing data extremes age, height, weight. We calculated prebronchodilator...
Thresholds for operative eligibility based on body mass index (BMI) alone may restrict patient access to the benefits of arthroplasty. The purpose this study was evaluate relationship between BMI and improvements in patient-reported outcome measures (PROMs), determine how many patients would have been denied PROMs if cut-offs were be implemented.A prospective cohort 3,449 primary total hip arthroplasties (THAs) performed 2015 2018 analyzed. following one-year evaluated: injury osteoarthritis...
Objectives: To identify the time at which point of care ultrasound static image recognition and acquisition skills decay in novice learners. Setting: The University Iowa Hospitals Clinics. Subjects: Twenty-four subjects (23 first-year medical students one physician assistant student). Design: completed an initial didactic hands-on session with immediate testing learned identification skills. Interventions: Retesting occurred 1, 4, 8 weeks after training no retraining between. Image were...
Both circulating adiponectin (APN) and cardiac APN exert cardioprotective effects improve insulin sensitivity mitochondrial function. Low serves as a biomarker for cardiovascular risk. Ablation of receptor 1 (AdipoR1) causes myocardial dysfunction. Although high salt intake is contributor to disease, how it modulates the expression or AdipoR1 in cardiomyocytes not known. We report that mRNA was attenuated dose-dependent manner mouse cardiomyocyte cell line HL-1 exposed concentrations ranging...
Herein, two simulated electrochemistry experiments, namely, the (i) electrochemical series, using an electronic half-cell module, and (ii) citrus fruit battery series are demonstrated for undergraduate chemistry students. The demonstration can be performed in-person remote students by connecting module to a computer. Remote participate in on Internet interact with instructor other This experiment does not require use of metal ion solutions construction batteries series. Therefore, this is...
<h3>BACKGROUND:</h3> The objective of our study was to identify variables associated with inhaled medication use in smokers normal spirometry (GOLD-0) and examine the association development exacerbations obstructive future. <h3>METHODS:</h3> We performed a retrospective multivariable analysis GOLD-0 subjects identified data from COPDGene factors use. Five categories were identified: (1) no medications, (2) short-acting bronchodilator, (3) long-acting bronchodilator; muscarinic antagonists...
Diabetic marker miRNA‐29 (miR‐29) is up‐regulated by pro‐inflammatory cytokines and hyperglycemia. miR‐29 induced suppression of MCL‐1, a protein essential for mitochondrial function cell survival, occurs in pancreatic β‐cell death. We hypothesized that conditions increase levels heart would promote MCL‐1 cardiomyocyte Since Rapamycin (Rap) known to diabetes, we further posited Rap treatment (750 µg/kg/day; 6 weeks) suppress tissues Zucker Fatty (ZDF) rat, rodent model the progression Type 2...
Diabetes Mellitus (DM) is an important risk factor for cardiovascular disease (CVD) and young, diabetic women are more susceptible to CVD compared age-matched men non-diabetic women. It unclear how the progression of DM differentially affects cardiac pathology in males females. In this context, recent studies have shown that myeloid cell leukemia 1 (MCL-1) plays role protection cardiac-specific ablation Mcl-1 causes fatal dilated cardiomyopathy. We hypothesized there a gender difference...
Objectives: Athletes commonly wear fitted silicone ankle sleeves (SAS) and lace-up braces (LAB). There is limited data about their effect on neuromuscular control or athletic performance. Our goal to evaluate efficacy in a young, active population during tasks using motion analysis. Methods: Ten subjects (5 males, 5 females) without prior musculoskeletal injury were recruited. They asked perform the Drop Vertical Jump test (DVJ), 45 degree bound, cutting maneuvers under three conditions: No...
Angiotensin II (Ang II) receptor AT2R is a member of the vasodilative/anti‐inflammatory branch renin‐angiotensin system (RAS). However, mechanisms underlying regulation expression in cardiomyocytes are not understood. To determine how vasodilative insulin (INS) and anti‐inflammatory drug rapamycin (Rap) modulate expression, we performed radioligand binding experiments with 125 I‐CGP42112A, an AT2 specific ligand, on mouse atrial cardiomyocyte HL‐1 cells. INS (100nM, 12h) increased functional...