A5043323929- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Cardiac Arrest and Resuscitation
- Inhalation and Respiratory Drug Delivery
- Neonatal Respiratory Health Research
- Nosocomial Infections in ICU
- Cardiac, Anesthesia and Surgical Outcomes
- Pneumothorax, Barotrauma, Emphysema
- Non-Invasive Vital Sign Monitoring
- Asthma and respiratory diseases
- Emergency and Acute Care Studies
- COVID-19 epidemiological studies
- Hemodynamic Monitoring and Therapy
- COVID-19 and Mental Health
- Mechanical Circulatory Support Devices
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Infection Control and Ventilation
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- COVID-19 Pandemic Impacts
- Simulation-Based Education in Healthcare
Rush University
2016-2025
Rush University Medical Center
2017-2024
University of Illinois Chicago
2024
Jesse Brown VA Medical Center
2024
University of Chicago
2024
University of Illinois Hospital & Health Sciences System
2024
Northwestern University
2024
University of Illinois Urbana-Champaign
2024
University of Alabama at Birmingham
2012
The University of Texas Health Science Center at San Antonio
2000-2009
Abstract Background Awake prone positioning (APP) improves oxygenation in coronavirus disease (COVID-19) patients and, when successful, may decrease the risk of intubation. However, factors associated with APP success remain unknown. In this secondary analysis, we aimed to assess whether can reduce intubation rate COVID-19 and focus on success. Methods multicenter randomized controlled trial, conducted three high-acuity units, randomly assigned COVID-19-induced acute hypoxemic respiratory...
Importance The impact of awake prone positioning (APP) on clinical outcomes in patients with COVID-19 and acute hypoxemic respiratory failure (AHRF) remains uncertain. Objective To assess the association APP improved among AHRF, to identify potential effect modifiers. Data Sources PubMed, Embase, Cochrane Library, ClinicalTrials.gov were searched through August 1, 2024. Study Selection Randomized trials (RCTs) examining adults AHRF that reported intubation rate or mortality included....
Awake prone positioning (APP) is widely used in the management of patients with coronavirus disease (COVID-19). The primary objective this study was to compare outcome COVID-19 who received early versus late APP.Post hoc analysis data collected for a randomized controlled trial (ClinicalTrials.gov NCT04325906). Adult acute hypoxemic respiratory failure secondary APP at least one hour were included. Early defined as initiated within 24 h high-flow nasal cannula (HFNC) start. Primary outcomes...
<b>Wearing a surgical/procedure mask over high-flow nasal cannula (HFNC) reduces aerosol particle concentrations in the patients' vicinity. Wearing HFNC should be encouraged to reduce risks of transmission. #COVID19</b>https://bit.ly/2HLg5cE
Abstract Background Awake prone positioning (APP) reduces the intubation rate in COVID-19 patients treated by high-flow nasal cannula (HFNC). However, lung aeration response to APP has not been addressed. We aimed explore ultrasound (LUS). Methods This two-center, prospective, observational study enrolled with COVID-19-induced acute hypoxemic respiratory failure HFNC and APP. LUS score was recorded 5–10 min before, 1 h after APP, supine first session within three days. The primary outcome...
Oxygen therapy for patients with COPD and severe hypoxemia requires the use of oxygen delivery devices that allow mobility as needed. However, characteristics some may limit freedom individuals to be physically active they desire. Limited negatively affect perceived quality life COPD. The aim this study was understand limitations experience in using long-term (LTOT) devices.We performed a qualitative analysis 311 responses an open-ended question from previously deployed electronic survey...
Inhaled epoprostenol (iEPO) has been utilized to improve oxygenation in mechanically ventilated subjects with severe hypoxemia, but the evidence for iEPO via high-flow nasal cannula (HFNC) is rare. Following approval by institutional review board, this retrospective cohort study evaluated who received HFNC more than 30 min treat hypoxemia comorbid pulmonary hypertension or right heart dysfunction between July 2015 and April 2018. A total of 11 were enrolled whom 4 male (36.4%), age 57.5 ±...
OVERVIEW Interprofessional practice in the ICU has been embraced as a standard of care since early origins Society Critical Care Medicine (SCCM) (1,2).This focus instrumental improving and outcomes patients with life-threatening illness injuries utilizing teams critical professionals (2). The team is typically comprised physicians, bedside nurses, nurse practitioners (NPs), physician assistants, clinical pharmacists, respiratory therapists (RTs), dieticians, physical/occupational therapists,...
(1) Background: inhaled epoprostenol (iEPO) delivered via high-flow nasal cannula (HFNC) has been reported to be effective for pulmonary hypertension and right ventricular dysfunction. In vitro studies have identified HFNC gas flow as a key factor in trans-nasal aerosol delivery efficiency; however, little evidence is available on the clinical impact of titration delivery. At our institution, iEPO was initiated 2015 concept during gradually accepted carried out by clinicians recent years....
<h3>BACKGROUND:</h3> Aerosolized epoprostenol is an alternative for inhaled nitric oxide in the management of pulmonary arterial hypertension and possibly acute hypoxemia. Our objective was to determine differences drug deposition based on different nebulizer positions ventilator circuit, using a vibrating mesh nebulizer. <h3>METHODS:</h3> An 8.0-mm inner diameter endotracheal tube (ETT) connected training test lung, compliance 30 mL/cm H<sub>2</sub>O, with collecting filter placed at...
Introduction Prone positioning (PP) is an effective first-line intervention to treat patients with moderate severe acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation, as it improves gas exchanges and reduces mortality. The use of PP in awake spontaneous breathing ARDS secondary COVID-19 was reported improve oxygenation few retrospective trials small sample size. High-level evidence for hypoxaemic still lacking. Methods analysis protocol this meta-trial a...
Early detection and prevention of extubation failure offers the potential to improve patient outcome. The primary aim this study was compare predictive ability Integrated Pulmonary Index presence high-risk factors in determining failure.A retrospective cross-sectional intubated adult subjects receiving mechanical ventilation for > 24 h conducted at an academic medical center. outcome failure, defined as need re-intubation or rescue noninvasive within 48 after planned extubation.Among 216...
<h3>BACKGROUND:</h3> In the first months of pandemic, prior to introduction proven-effective treatments, 15–37% patients hospitalized with COVID-19 were discharged on home oxygen. After treatments for acute established by evidence-based guidelines, little remains known about oxygen requirements following hospitalization COVID-19. <h3>METHODS:</h3> This was a retrospective, multi-center cohort study subjects between October 2020–September 2021 at 3 academic health centers. Information...
<h3>BACKGROUND:</h3> Although routine physical activity for individuals with COPD is recommended, there are inherent limitations of available oxygen delivery devices that may result in hypoxemia during activity. Changes Medicare laws have resulted an increased use cylinders and a reduction the liquid devices. The aim this survey was to assess impact perceived satisfaction various on mobility quality life (QOL) oxygen-dependent subjects COPD. <h3>METHODS:</h3> A developed measure current...
<h3>BACKGROUND:</h3> The integrated pulmonary index (IPI) utilizes an algorithm based on the measurement of end-tidal carbon dioxide, breathing frequency, heart rate, and oxygen saturation to provide assessment patient9s ventilatory status. This clinical trial was designed determine whether lower IPI values were associated with extubation failure. <h3>METHODS:</h3> prospective observational conducted in academic medical center. After institutional review board approval, 100 mechanically...
<h3>BACKGROUND:</h3> Endotracheal tube (ETT) scraping or sweeping refers to mucus removal from an ETT that can increase airway resistance. The study objective was evaluate the effect of on duration mechanical ventilation, time first successful spontaneous breathing trial (SBT), hospital stay, and occurrence ventilator-associated events (VAEs). <h3>METHODS:</h3> This a single-center, randomized clinical adult subjects intubated between October 2019–October 2021. Subjects were randomly...