- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Pulmonary Hypertension Research and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Ultrasound in Clinical Applications
- COVID-19 and healthcare impacts
- Cardiac Structural Anomalies and Repair
- Infection Control and Ventilation
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Obstructive Sleep Apnea Research
- Childhood Cancer Survivors' Quality of Life
- Health and Medical Research Impacts
- Clinical Nutrition and Gastroenterology
- Inhalation and Respiratory Drug Delivery
- Cardiac, Anesthesia and Surgical Outcomes
- Diet and metabolism studies
- Emergency and Acute Care Studies
- Innovations in Medical Education
- Medical Imaging and Pathology Studies
- Neonatal Respiratory Health Research
University of Michigan
2025
META Group
2025
Analysis Group (United States)
2025
Rush University Medical Center
2015-2023
Rush University
2018-2023
King's College School
2021
King's College London
2021
Allegheny Health Network
2019
University of Chicago Medical Center
2010
Awake prone positioning (APP) is widely used in the management of patients with coronavirus disease (COVID-19). The primary objective this study was to compare outcome COVID-19 who received early versus late APP.Post hoc analysis data collected for a randomized controlled trial (ClinicalTrials.gov NCT04325906). Adult acute hypoxemic respiratory failure secondary APP at least one hour were included. Early defined as initiated within 24 h high-flow nasal cannula (HFNC) start. Primary outcomes...
<b>Wearing a surgical/procedure mask over high-flow nasal cannula (HFNC) reduces aerosol particle concentrations in the patients' vicinity. Wearing HFNC should be encouraged to reduce risks of transmission. #COVID19</b>https://bit.ly/2HLg5cE
Abstract Background Awake prone positioning (APP) reduces the intubation rate in COVID-19 patients treated by high-flow nasal cannula (HFNC). However, lung aeration response to APP has not been addressed. We aimed explore ultrasound (LUS). Methods This two-center, prospective, observational study enrolled with COVID-19-induced acute hypoxemic respiratory failure HFNC and APP. LUS score was recorded 5–10 min before, 1 h after APP, supine first session within three days. The primary outcome...
Background: Bedside ultrasound is widely utilized for critically ill patients, yet there no standardized approach teaching lung to medical staff, particularly respiratory therapists (RTs), in the United States. Thus, we aimed evaluate efficacy of a training program designed RTs. Methods: With approval from ethics committee, recruited RTs with over 3 months experience at Rush University Medical Center participate our program. The comprised 1-h didactic lecture followed by hands-on practice on...
Inhaled epoprostenol (iEPO) has been utilized to improve oxygenation in mechanically ventilated subjects with severe hypoxemia, but the evidence for iEPO via high-flow nasal cannula (HFNC) is rare. Following approval by institutional review board, this retrospective cohort study evaluated who received HFNC more than 30 min treat hypoxemia comorbid pulmonary hypertension or right heart dysfunction between July 2015 and April 2018. A total of 11 were enrolled whom 4 male (36.4%), age 57.5 ±...
Introduction Prone positioning (PP) is an effective first-line intervention to treat patients with moderate severe acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation, as it improves gas exchanges and reduces mortality. The use of PP in awake spontaneous breathing ARDS secondary COVID-19 was reported improve oxygenation few retrospective trials small sample size. High-level evidence for hypoxaemic still lacking. Methods analysis protocol this meta-trial a...
Objectives: To evaluate the effects of inhaled epoprostenol and prone positioning, individually in combination mechanically ventilated patients with coronavirus disease 2019 refractory hypoxemia. Design: Retrospective study. Setting: Academic hospital adult ICUs. Patients: Adult who received positioning during invasive ventilation were enrolled. Patients excluded if was initiated: 1) at an outside hospital, 2) after terminated, 3) extracorporeal membrane oxygenation or cardiopulmonary...
High-flow nasal cannula (HFNC) oxygen therapy is used to deliver warm and humidified gases patients in respiratory failure. A purported advantage of HFNC that it can allow for oral feeding while on the device, although few data support this practice. The purpose study was identify practices opinions with regard during therapy.
The optimal timing of surgical treatment for infective endocarditis complicated by cerebrovascular events is controversial, largely due to the perceived risk perioperative intracranial bleeding. Current guidelines suggest waiting 2 weeks between diagnosis stroke and surgery. aim this study was investigate clinical neurological outcomes early surgery following a stroke.This single-center retrospective analysis 12 consecutive patients requiring 2011 2014 at Rush University Medical Center, with...
Prone positioning is known to reduce mortality among patients on mechanical ventilation with moderate-to-severe ARDS.[1][1] When extrapolating data about these ARDS, awake prone touted as a low-risk intervention that can be performed outside the ICU. Studies show
The indications for urgent valve replacement in patients with infective endocarditis (IE) include uncontrolled infection, recurrent emboli, dysfunction and cardiac failure. optimal timing of this surgery when IE is complicated by cerebrovascular events (such as cerebral infarction or haemorrhage) controversial, largely due to the escalated risk perioperative intracranial bleeding, given that patient fully anticoagulated on cardiopulmonary bypass procedure. While current guidelines suggest...
Web ExclusivesDecember 2021Annals Graphic Medicine - A Differing PerspectiveFREESara MirzaSara MirzaKing's College London, United Kingdom (S.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/G21-0019 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Download figure PowerPoint Comments0 CommentsSign In Submit Comment Ibrahim GhobrialUPMC Mercy13...