Sara Mirza

ORCID: 0000-0003-1378-3502
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • Pulmonary Hypertension Research and Treatments
  • Pneumothorax, Barotrauma, Emphysema
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Mechanical Circulatory Support Devices
  • Intensive Care Unit Cognitive Disorders
  • Ultrasound in Clinical Applications
  • COVID-19 and healthcare impacts
  • Cardiac Structural Anomalies and Repair
  • Infection Control and Ventilation
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Obstructive Sleep Apnea Research
  • Childhood Cancer Survivors' Quality of Life
  • Health and Medical Research Impacts
  • Clinical Nutrition and Gastroenterology
  • Inhalation and Respiratory Drug Delivery
  • Cardiac, Anesthesia and Surgical Outcomes
  • Diet and metabolism studies
  • Emergency and Acute Care Studies
  • Innovations in Medical Education
  • Medical Imaging and Pathology Studies
  • Neonatal Respiratory Health Research

University of Michigan
2025

META Group
2025

Analysis Group (United States)
2025

Rush University Medical Center
2015-2023

Rush University
2018-2023

King's College School
2021

King's College London
2021

Allegheny Health Network
2019

University of Chicago Medical Center
2010

Stéphan Ehrmann Jie Li Miguel Ibarra‐Estrada Yonatan Perez Ivan Petrovitch Pavlov and 95 more Alistair Nichol Oriol Roca Sara Mirza David Vines Roxana García-Salcido Guadalupe Aguirre-Ávalos Matthew W Trump Mai-Anh Nay Jean Dellamonica Saad Nseir Idrees Mogri David Cosgrave Dev Jayaraman Joan Ramón Masclans John G. Laffey Elsa Tavernier Jie Li Sara Mirza David Vines Ahmad A Elshafei Brady J Scott Tyler Weiss Ramandeep Kaur Lauren J Harnois Amanda Miller Flor Cerda Andrew M. Klein Jacob R Burd Kathleen Posa-Kearney Matthew W Trump Julie Jackson Trevor W Oetting Mark Greenwood L. N. Hazel Lisa K Kingery Idrees Mogri Lindsey Morris Joon Yong Moon Julianne Garnett Shijing Jia Kristine Nelson Alistair Nichol David Cosgrave Camilla Giacomini John G. Laffey Aoife Brennan Conor Judge Maeve Kernan Claire Kelly Ritika Ranjan Siobhán Casey Kevin S. O’Connell Evelyn Newell David Gallagher Alistair Nichol Ger Curley Miguel Ibarra‐Estrada Roxana García-Salcido Alexandra Vargas-Obieta Guadalupe Aguirre-Ávalos Sara A. Aguirre-Díaz Luz Alcántar-Vallín Montserrat Alvarado-Padilla Quetzalcóatl Chávez-Peña José Arnulfo López Pulgarín Julio Mijangos Miguel Marín‐Rosales Jorge E García-Alvarado Oscar G Baltazar-González Maura Cecilia Gonzalez-Guerrero Paola G Gutiérrez Ramírez Ivan Petrovitch Pavlov Sean Gilman Patrice Plamondon Rachel Roy Dev Jayaraman Jason Shahin Raham Ragoshai Aasmine Kaur Josie Campisi Joseph Dahine S. Perron Slimane Achouri Ronald Racette Anne Kulenkamp Oriol Roca Andrés Pacheco Marina García-de-Acilu Joan Ramón Masclans Irene Dot Yonatan Perez Laetitia Contentin Denis Garot Stéphan Ehrmann Emmanuelle Mercier

10.1016/s2213-2600(21)00356-8 article EN The Lancet Respiratory Medicine 2021-08-20

Awake prone positioning (APP) is widely used in the management of patients with coronavirus disease (COVID-19). The primary objective this study was to compare outcome COVID-19 who received early versus late APP.Post hoc analysis data collected for a randomized controlled trial (ClinicalTrials.gov NCT04325906). Adult acute hypoxemic respiratory failure secondary APP at least one hour were included. Early defined as initiated within 24 h high-flow nasal cannula (HFNC) start. Primary outcomes...

10.1186/s13054-021-03761-9 article EN cc-by Critical Care 2021-09-17

<b>Wearing a surgical/procedure mask over high-flow nasal cannula (HFNC) reduces aerosol particle concentrations in the patients' vicinity. Wearing HFNC should be encouraged to reduce risks of transmission. #COVID19</b>https://bit.ly/2HLg5cE

10.1183/23120541.00519-2020 article EN cc-by-nc ERJ Open Research 2020-10-29

Abstract Background Awake prone positioning (APP) reduces the intubation rate in COVID-19 patients treated by high-flow nasal cannula (HFNC). However, lung aeration response to APP has not been addressed. We aimed explore ultrasound (LUS). Methods This two-center, prospective, observational study enrolled with COVID-19-induced acute hypoxemic respiratory failure HFNC and APP. LUS score was recorded 5–10 min before, 1 h after APP, supine first session within three days. The primary outcome...

10.1186/s13054-022-04064-3 article EN cc-by Critical Care 2022-06-27

Background: Bedside ultrasound is widely utilized for critically ill patients, yet there no standardized approach teaching lung to medical staff, particularly respiratory therapists (RTs), in the United States. Thus, we aimed evaluate efficacy of a training program designed RTs. Methods: With approval from ethics committee, recruited RTs with over 3 months experience at Rush University Medical Center participate our program. The comprised 1-h didactic lecture followed by hands-on practice on...

10.1089/respcare.12291 article EN Respiratory Care 2025-03-07

Inhaled epoprostenol (iEPO) has been utilized to improve oxygenation in mechanically ventilated subjects with severe hypoxemia, but the evidence for iEPO via high-flow nasal cannula (HFNC) is rare. Following approval by institutional review board, this retrospective cohort study evaluated who received HFNC more than 30 min treat hypoxemia comorbid pulmonary hypertension or right heart dysfunction between July 2015 and April 2018. A total of 11 were enrolled whom 4 male (36.4%), age 57.5 ±...

10.3390/pharmaceutics11060281 article EN cc-by Pharmaceutics 2019-06-14

Introduction Prone positioning (PP) is an effective first-line intervention to treat patients with moderate severe acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation, as it improves gas exchanges and reduces mortality. The use of PP in awake spontaneous breathing ARDS secondary COVID-19 was reported improve oxygenation few retrospective trials small sample size. High-level evidence for hypoxaemic still lacking. Methods analysis protocol this meta-trial a...

10.1136/bmjopen-2020-041520 article EN cc-by-nc BMJ Open 2020-11-01

Objectives: To evaluate the effects of inhaled epoprostenol and prone positioning, individually in combination mechanically ventilated patients with coronavirus disease 2019 refractory hypoxemia. Design: Retrospective study. Setting: Academic hospital adult ICUs. Patients: Adult who received positioning during invasive ventilation were enrolled. Patients excluded if was initiated: 1) at an outside hospital, 2) after terminated, 3) extracorporeal membrane oxygenation or cardiopulmonary...

10.1097/cce.0000000000000307 article EN cc-by-nc-nd Critical Care Explorations 2020-12-01

High-flow nasal cannula (HFNC) oxygen therapy is used to deliver warm and humidified gases patients in respiratory failure. A purported advantage of HFNC that it can allow for oral feeding while on the device, although few data support this practice. The purpose study was identify practices opinions with regard during therapy.

10.4187/respcare.10469 article EN Respiratory Care 2023-04-18

The optimal timing of surgical treatment for infective endocarditis complicated by cerebrovascular events is controversial, largely due to the perceived risk perioperative intracranial bleeding. Current guidelines suggest waiting 2 weeks between diagnosis stroke and surgery. aim this study was investigate clinical neurological outcomes early surgery following a stroke.This single-center retrospective analysis 12 consecutive patients requiring 2011 2014 at Rush University Medical Center, with...

10.1177/0218492316652746 article EN Asian Cardiovascular and Thoracic Annals 2016-05-26

Prone positioning is known to reduce mortality among patients on mechanical ventilation with moderate-to-severe ARDS.[1][1] When extrapolating data about these ARDS, awake prone touted as a low-risk intervention that can be performed outside the ICU. Studies show

10.4187/respcare.09905 article EN Respiratory Care 2022-06-14

The indications for urgent valve replacement in patients with infective endocarditis (IE) include uncontrolled infection, recurrent emboli, dysfunction and cardiac failure. optimal timing of this surgery when IE is complicated by cerebrovascular events (such as cerebral infarction or haemorrhage) controversial, largely due to the escalated risk perioperative intracranial bleeding, given that patient fully anticoagulated on cardiopulmonary bypass procedure. While current guidelines suggest...

10.1186/1749-8090-10-s1-a56 article EN cc-by Journal of Cardiothoracic Surgery 2015-12-01

Web ExclusivesDecember 2021Annals Graphic Medicine - A Differing PerspectiveFREESara MirzaSara MirzaKing's College London, United Kingdom (S.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/G21-0019 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Download figure PowerPoint Comments0 CommentsSign In Submit Comment Ibrahim GhobrialUPMC Mercy13...

10.7326/g21-0019 article EN Annals of Internal Medicine 2021-12-01
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