Nicola Latronico
A5017639441- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- COVID-19 Clinical Research Studies
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury Research
- Hemodynamic Monitoring and Therapy
- Acute Ischemic Stroke Management
- Palliative Care and End-of-Life Issues
- Organ Donation and Transplantation
- Intracranial Aneurysms: Treatment and Complications
- Child and Adolescent Health
- Anesthesia and Pain Management
- Peripheral Neuropathies and Disorders
- Airway Management and Intubation Techniques
- Trauma and Emergency Care Studies
- S100 Proteins and Annexins
University of Brescia
2016-2025
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2016-2025
Brescia University
1992-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2003-2021
Azienda Sanitaria Unità Locale di Reggio Emilia
2020-2021
Mario Negri Institute for Pharmacological Research
2003-2016
University of Milano-Bicocca
2016
Azienda Ospedaliera San Gerardo
2016
Harvard University
2006-2015
Massachusetts General Hospital
2015
In December 2019, a novel coronavirus (severe acute respiratory syndrome 2 [SARS-CoV-2]) emerged in China and has spread globally, creating pandemic. Information about the clinical characteristics of infected patients who require intensive care is limited.To characterize with disease 2019 (COVID-19) requiring treatment an unit (ICU) Lombardy region Italy.Retrospective case series 1591 consecutive laboratory-confirmed COVID-19 referred for ICU admission to coordinator center (Fondazione IRCCS...
<h3>Importance</h3> Many patients with coronavirus disease 2019 (COVID-19) are critically ill and require care in the intensive unit (ICU). <h3>Objective</h3> To evaluate independent risk factors associated mortality of COVID-19 requiring treatment ICUs Lombardy region Italy. <h3>Design, Setting, Participants</h3> This retrospective, observational cohort study included 3988 consecutive laboratory-confirmed referred for ICU admission to coordinating center (Fondazione IRCCS [Istituto di...
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To assess the knowledge and use of Assessment, prevention, management pain; spontaneous awakening breathing trials; Choice analgesia sedation; Delirium assessment; Early mobility exercise; Family engagement empowerment (ABCDEF) bundle to implement Pain, Agitation, guidelines.Worldwide online survey.Intensive care.A cross-sectional survey using Delphi method was administered intensivists worldwide, all aspects ABCDEF bundle.There were 1,521 respondents from 47 countries, 57% had implemented...
Abstract Intensive care survivors often experience post-intensive sequelae, which are frequently gathered together under the term “post-intensive syndrome” (PICS). The consequences of PICS on quality life, health-related costs and hospital readmissions real public health problems. In present Viewpoint, we summarize current knowledge gaps in our understanding approaches to management.
Abstract Sepsis, or systemic inflammatory response syndrome, is the major cause of critical illness resulting in admission to intensive care units. Sepsis caused by severe infection and associated with mortality 60% cases. Morbidity due sepsis complicated neuromyopathy, patients face long-term disability muscle weakness, energetic dysfunction, proteolysis wasting. These processes are triggered pro-inflammatory cytokines metabolic imbalances aggravated malnutrition drugs. Skeletal...
Single cases and small series of Guillain-Barré syndrome (GBS) have been reported during the SARS-CoV-2 outbreak worldwide. We evaluated incidence clinical features GBS in a cohort patients from two regions northern Italy with highest number COVID-19.GBS diagnosed 12 referral hospitals Lombardy Veneto March April 2020 were retrospectively collected. As control population, 2019 same considered.Incidence was 0.202/100 000/month (estimated rate 2.43/100 000/year) vs 0.077/100 0.93/100 months...
An ongoing pandemic of COVID-19 that started in Hubei, China has resulted massive strain on the healthcare infrastructure Lombardy, Italy. The management these patients is still evolving.
Rationale: Treatment with noninvasive ventilation (NIV) in coronavirus disease (COVID-19) is frequent. Shortage of intensive care unit (ICU) beds led clinicians to deliver NIV also outside ICUs. Data about the use COVID-19 limited.Objectives: To describe prevalence and clinical characteristics patients treated investigate factors associated failure (need for intubation or death).Methods: In this prospective, single-day observational study, we enrolled adult who were ICU from 31 hospitals...
We report on the outcome of 114 COVID-19-associated acute respiratory distress syndrome (ARDS) survivors evaluated at 3, 6 and 12 months after intensive care unit discharge with assessment physical, mental cognitive impairments. Critical illness polyneuromyopathy was diagnosed in 23 patients (39%). Handgrip dynamometry 70% predicted 3 significantly improved over time, whereas min walk test (80% predicted) severe fatigue (27% patients) did not. Independence activities daily living (ADL)...
Postoperative delirium (POD) remains a common, dangerous and resource-consuming adverse event but is often preventable. The whole peri-operative team can play key role in its management. This update to the 2017 ESAIC Guideline on prevention of POD evidence-based consensus-based considers literature between 01 April 2015, 28 February 2022. search terms broad were identical those used first version guideline published 2017. was defined accordance with DSM-5 criteria. had be measured validated...
<h3>Background:</h3> Critical illness myopathy (CIM) and polyneuropathy (CIP), alone or in combination (CIP/CIM), are frequent complications patients the intensive care unit (ICU). There is no evidence that differentiating between CIP CIM has any impact on patient prognosis. <h3>Methods:</h3> 1-year prospective cohort study of developing CIP, combined during ICU stay. <h3>Results:</h3> 28 out 92 (30.4%) developed electrophysiological signs and/or their stay, which persisted 18 at discharge....
Abstract Introduction Critical illness myopathy and/or neuropathy (CRIMYNE) is frequent in intensive care unit (ICU) patients. Although complete electrophysiological tests of peripheral nerves and muscles are essential to diagnose it, they time-consuming, precluding extensive use daily ICU practice. We evaluated whether a simplified investigation only two could be used as an alternative tests. Methods In this prospective, multi-centre study, 92 patients were subjected unilateral measurements...