Anna Mara Scandroglio
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Acute Kidney Injury Research
- Cardiac and Coronary Surgery Techniques
- COVID-19 and healthcare impacts
- Hemodynamic Monitoring and Therapy
- Infective Endocarditis Diagnosis and Management
- Cardiac Ischemia and Reperfusion
- Sepsis Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Pneumothorax, Barotrauma, Emphysema
- Anesthesia and Neurotoxicity Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Ultrasound in Clinical Applications
- Anesthesia and Sedative Agents
Vita-Salute San Raffaele University
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2016-2025
IRCCS Ospedale San Raffaele
2017-2025
San Raffaele University of Rome
2020-2024
Maasstad Ziekenhuis
2023
Erasmus MC
2023
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo
2023
May Institute
2023
Tianjin Third Central Hospital
2017
In December 2019, a novel coronavirus (severe acute respiratory syndrome 2 [SARS-CoV-2]) emerged in China and has spread globally, creating pandemic. Information about the clinical characteristics of infected patients who require intensive care is limited.To characterize with disease 2019 (COVID-19) requiring treatment an unit (ICU) Lombardy region Italy.Retrospective case series 1591 consecutive laboratory-confirmed COVID-19 referred for ICU admission to coordinator center (Fondazione IRCCS...
We suggest the use of MicroCLOTS (microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome) as a new name for severe pulmonary coronavirus disease 2019 (COVID-19). hypothesise that, in predisposed individuals, alveolar viral damage is followed by an inflammatory reaction and microvascular thrombosis. This progressive endothelial syndrome may also involve bed brain other vital organs, leading to multiple organ failure death. Future steps understanding identification...
Abstract Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many—sometimes contradictory—observations regarding patient selection, surgical techniques, perioperative management follow-up have been published. With the growing expertise in this field, European Association Cardio-Thoracic Surgery (EACTS) recognized a need structured multidisciplinary consensus about approach to LT-MCS....
Acute left ventricular dysfunction is a major complication of cardiac surgery and associated with increased mortality. Meta-analyses small trials suggest that levosimendan may result in higher rate survival among patients undergoing surgery.
Describe characteristics, daily care and outcomes of patients with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS).Case series 73 patients.Large tertiary hospital in Milan.Mechanically ventilated confirmed COVID-19 admitted to the intensive unit (ICU) between 20 February 2 April 2020.Demographic clinical data were collected identify predictors early mortality.Of included study, most male (83.6%), median age was 61 years (interquartile range [IQR], 54-69 years),...
At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak spread from China all around world, causing thousands deaths. In Italy, hardest hit region was Lombardy, with first reported case on 20 February 2020. San Raffaele Scientific Institute — a large tertiary hospital and research centre in Milan, Italy immediately involved management public health emergency. Since beginning outbreak, elective surgical activity rapidly reduced areas were simultaneously...
Volatile (inhaled) anesthetic agents have cardioprotective effects, which might improve clinical outcomes in patients undergoing coronary-artery bypass grafting (CABG).We conducted a pragmatic, multicenter, single-blind, controlled trial at 36 centers 13 countries. Patients scheduled to undergo elective CABG were randomly assigned an intraoperative regimen that included volatile (desflurane, isoflurane, or sevoflurane) total intravenous anesthesia. The primary outcome was death from any...
Objective To assess the prevalence, characteristics and prognostic value of pulmonary hypertension (PH) right ventricular dysfunction (RVD) in hospitalised, non-intensive care unit (ICU) patients with coronavirus disease 2019 (COVID-19). Methods This single-centre, observational, cross-sectional study included 211 COVID-19 admitted to non-ICU departments who underwent a single transthoracic echocardiography (TTE). Patients poor acoustic window (n=11) were excluded. Clinical, imaging,...
Meropenem is a widely prescribed β-lactam antibiotic. exhibits maximum pharmacodynamic efficacy when given by continuous infusion to deliver constant drug levels above the minimal inhibitory concentration. Compared with intermittent administration, administration of meropenem may improve clinical outcomes.To determine whether reduces composite mortality and emergence pandrug-resistant or extensively drug-resistant bacteria compared in critically ill patients sepsis.A double-blind, randomized...
Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced perfusion key contributing factor. Intravenous amino acids increase recruit renal functional reserve. However, the efficacy in reducing occurrence AKI after surgery uncertain.
No effective pharmaceutical agents have yet been identified to treat acute kidney injury after cardiac surgery.To determine whether fenoldopam reduces the need for renal replacement therapy in critically ill surgery patients with injury.Multicenter, randomized, double-blind, placebo-controlled, parallel-group study from March 2008 April 2013 19 cardiovascular intensive care units Italy. We randomly assigned 667 admitted early (≥50% increase of serum creatinine level baseline or oliguria ≥6...
The coronavirus disease-2019 (COVID-19) pandemic has caused an enormous strain on healthcare systems and society a global scale. We report new phenomenon of medical care avoidance among patients with acute coronary syndrome, which is due to concerns about contracting severe respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection during hospital stay, ultimately leading dire clinical outcomes. (Level Difficulty: Beginner.)
Background: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. Objective: To study the prevalence, characteristics, risk factors outcome of AKI CRRT COVID-19 patients. Methods: Observational a tertiary care hospital Milan, Italy. Results: Among 99 patients, 72 (75.0%) developed 17 (17.7%) received CRRT. Most stage 1 (33 [45.8%]), while 15...
Importance Data on the association of COVID-19 vaccination with intensive care unit (ICU) admission and outcomes patients SARS-CoV-2–related pneumonia are scarce. Objective To evaluate whether is associated preventing ICU for to compare baseline characteristics vaccinated unvaccinated admitted an ICU. Design, Setting, Participants This retrospective cohort study regional data sets reports: (1) daily number administered vaccines (2) all consecutive in Lombardy, Italy, from August 1 December...