Bas C. T. van Bussel
A5056785549- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Cardiac Arrest and Resuscitation
- Nutritional Studies and Diet
- Venous Thromboembolism Diagnosis and Management
- Machine Learning in Healthcare
- Heart Failure Treatment and Management
- Clinical Reasoning and Diagnostic Skills
- Retinal and Optic Conditions
- COVID-19 diagnosis using AI
- Cardiovascular Disease and Adiposity
- Birth, Development, and Health
- Muscle and Compartmental Disorders
- Dermatological and COVID-19 studies
- Cerebrovascular and Carotid Artery Diseases
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Emergency and Acute Care Studies
Maastricht University Medical Centre
2013-2025
Maastricht University
2011-2025
University Medical Center
2024
University Medical Center Groningen
2024
University of Groningen
2024
Zorginstituut Nederland
2022-2023
Cardiovascular Institute Hospital
2023
Hospital Clínic de Barcelona
2023
University of Amsterdam
2022
TiFN
2011-2015
Sharing healthcare data is increasingly essential for developing data-driven improvements in patient care at the Intensive Care Unit (ICU). However, it also very challenging under strict privacy legislation of European Union (EU). Therefore, we explored four successful open ICU databases to determine how can be shared appropriately EU. A questionnaire was constructed based on Delphi method. Then, follow-up questions were discussed with experts from databases. These encountered similar...
IntroductionIn the first wave, thrombotic complications were common in COVID-19 patients. It is unknown whether state-of-the-art treatment has resulted less second wave.MethodsWe assessed incidence of and overall mortality patients admitted to eight Dutch hospitals between September 1st November 30th 2020. Follow-up ended at discharge, transfer another hospital, when they died, or on 2020, whichever came first. Cumulative incidences estimated, adjusted for competing risk death. These...
OBJECTIVES: We performed a comprehensive health assessment in mechanically ventilated coronavirus disease 2019 survivors to assess the impact of respiratory and skeletal muscle injury sustained during ICU stay on physical performance at 3 months following hospital discharge. DESIGN: Preregistered prospective observational cohort study. SETTING: University ICU. PATIENTS: All patients admitted our first European pandemic wave. MEASUREMENTS AND MAIN RESULTS: At after discharge, 46 underwent...
Abstract Background To assess trends in the quality of care for COVID-19 patients at ICU over course time Netherlands. Methods Data from National Intensive Care Evaluation (NICE)-registry all admitted to an Netherlands were used. Patient characteristics and indicators during first two upsurges (N = 4215: October 5, 2020–January 31, 2021) final upsurge second wave, called ‘third wave’ 4602: February 1, 2021–June 30, compared with those wave 2733, February–May 24, 2020). Results During third...
Background Extracorporeal membrane oxygenation (ECMO) has been increasingly used for postcardiotomy cardiogenic shock, but without a concomitant reduction in observed in-hospital mortality. Long-term outcomes are unknown. This study describes patients' characteristics, outcome, and 10-year survival after ECMO. Variables associated with postdischarge mortality investigated reported. Methods Results The retrospective international multicenter observational PELS-1 (Postcardiotomy Life Support)...
Abstract Background Previously, we reported a decreased mortality rate among patients with COVID-19 who were admitted at the ICU during final upsurge of second wave (February–June 2021) in Netherlands. We examined whether this decrease persisted third and phases decreasing incidence thereafter brought up to date information on patient characteristics. Methods Data from National Intensive Care Evaluation (NICE)-registry all an Netherlands used. Patient characteristics rates in-hospital (the...
Unobtrusive pulse rate monitoring by continuous video recording, based on remote photoplethysmography (rPPG), might enable early detection of perioperative arrhythmias in general ward patients. However, the accuracy an rPPG-based machine learning model to monitor during sinus rhythm and is unknown. We conducted a prospective, observational diagnostic study cohort with high prevalence (patients undergoing elective electrical cardioversion). Pulse was assessed rPPG via visible light camera ECG...
Patients with cardiac disease are considered high risk for poor outcomes following hospitalization COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart subtypes and in-hospital mortality.
Background: Coronavirus Disease 2019 (COVID-19) patients often present with thromboembolic events. In COVID-19 patients, routine hemostatic assays cannot correctly identify at risk for Viscoelastic testing rotational thromboelastometry (ROTEM) might improve the characterization of COVID-19-associated coagulopathy. Objective: To unravel underlying coagulopathy and fibrinolysis over time as measured by serial assessment heparin-independent (FIBTEM EXTEM) illustrating (tissue plasminogen...
Abstract Objectives To investigate whether adherence to a M editerranean dietary pattern during adolescence and early adulthood affects arterial stiffness in adulthood, the extent which any such association may be attributed beneficial impact of this diet on cardiovascular disease risk factors as blood pressure, central fatness dyslipidaemia. Setting The A msterdam G rowth H ealth L ongitudinal S tudy. Design subjects We compared longitudinal levels (a MED score with range 0–9) (two eight...
The course of the disease in SARS-CoV-2 infection mechanically ventilated patients is unknown. To unravel clinical heterogeneity these patients, we designed prospective observational Maastricht Intensive Care COVID cohort (MaastrICCht). We incorporated serial measurements that harbour aetiological, diagnostic and predictive information. study aims to investigate natural critically ill with a infection.Mechanically admitted intensive care will be included. collect variables, vital parameters,...
Abstract Objective Severe cases of coronavirus disease 2019 (COVID-19) can require continuous renal replacement therapy (CRRT) and/or extracorporeal membrane oxygenation (ECMO). Unfractionated heparin (UFH) to prevent circuit clotting is mandatory but monitoring complicated by (pseudo)-heparin resistance. In this observational study, we compared two different activated partial thromboplastin time (aPTT) assays and a chromogenic anti-Xa assay in COVID-19 patients on CRRT or ECMO relation...
ObjectivesPostcardiotomy extracorporeal membrane oxygenation (ECMO) can be initiated intraoperatively or postoperatively based on indications, settings, patient profile, and conditions. The topic of implantation timing only recently gained attention from the clinical community. We compare characteristics as well in-hospital long-term survival between intraoperative postoperative ECMO.MethodsThe retrospective, multicenter, observational Postcardiotomy Extracorporeal Life Support (PELS-1)...
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes disease 2019 (COVID-19). Commonly used methods for both clinical diagnosis of SARS-CoV-2 infection and management infected patients involve the detection viral RNA, but presence infectious virus particles is unknown. Viability PCR (v-PCR) uses a photoreactive dye to bind non-infectious ideally resulting in RNA only from intact virions. This study aimed develop validate rapid v-PCR assay distinguishing compromised...