José Barberán
A5054983183- Pneumonia and Respiratory Infections
- Antifungal resistance and susceptibility
- Nosocomial Infections in ICU
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Orthopedic Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Streptococcal Infections and Treatments
- Respiratory and Cough-Related Research
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Fungal Infections and Studies
- Appendicitis Diagnosis and Management
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Intensive Care Unit Cognitive Disorders
- Diabetic Foot Ulcer Assessment and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infective Endocarditis Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Wound Healing and Treatments
- Drug-Induced Adverse Reactions
Hospital Universitario HM Madrid
2016-2025
Universidad San Pablo CEU
2014-2025
HM Hospitales
2021-2025
Camilo José Cela University
2023-2025
Clinica Universidad de Navarra
2022-2023
Hospital Universitario de Getafe
2022-2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2022-2023
Instituto de Salud Carlos III
2023
Universidad Laica Eloy Alfaro de Manabí
2018-2023
Hospital General Universitario Gregorio Marañón
2023
Sharing healthcare data is increasingly essential for developing data-driven improvements in patient care at the Intensive Care Unit (ICU). However, it also very challenging under strict privacy legislation of European Union (EU). Therefore, we explored four successful open ICU databases to determine how can be shared appropriately EU. A questionnaire was constructed based on Delphi method. Then, follow-up questions were discussed with experts from databases. These encountered similar...
Plitidepsin, a marine-derived cyclic-peptide, inhibits SARS-CoV-2 replication at nanomolar concentrations by targeting the host protein eukaryotic translation elongation factor 1A. Here, we show that plitidepsin distributes preferentially to lung over plasma, with similar potency against across several variants in preclinical studies. Simultaneously, this randomized, parallel, open-label, proof-of-concept study (NCT04382066) conducted 10 Spanish hospitals between May and November 2020, 46...
The high transmissibility of SARS-CoV-2 before and shortly after the onset symptoms suggests that only diagnosing isolating symptomatic patients may not be sufficient to interrupt spread infection; therefore, public health measures such as personal distancing are also necessary. Additionally, it will important detect newly infected individuals who remain asymptomatic, which account for 50% or more cases. Molecular techniques “gold standard” diagnosis infection. However, massive use these has...
The primary aim of our study was to investigate the association between intubation timing and hospital mortality in critically ill patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure. We also analysed both impact such throughout first four pandemic waves influence prior noninvasive support on outcomes.This is a secondary analysis multicentre, observational prospective cohort that included all consecutive undergoing invasive mechanical ventilation due COVID-19...
Although the prevalence of community-acquired respiratory bacterial coinfection upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been reported to be < 5%, almost three-quarters received antibiotics. We aim investigate whether procalcitonin (PCT) or C-reactive protein (CRP) could helpful biomarkers identify among COVID-19 pneumonia. carried out a multicentre, observational cohort study including consecutive admitted 55 Spanish intensive care units (ICUs). The...
Los rubros en los que se incurre la producción de cerdos determinan alrededor del 50 % costo productivo actividad. La cerveza artesanal produce residuos sólidos, mismos al ser tratados pueden considerados para usarlos como alimento, es por esto el objetivo presente investigación caracterizar componentes químicos provenientes elaboración donde obtuvieron valores materia seca 84.77 %, ceniza 2.54 grasa 1.98 fibra cruda 4.85 proteína 10.86 extracto libre nitrógeno y total nutrientes digestibles...
Abstract Background Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study investigate associations between mortality and variables measured during first three days ventilation with intubated at ICU admission. Methods Multicenter, observational, cohort includes consecutive admitted 44 Spanish ICUs February 25 July 31, 2020, who required intubation admission for more than days. We collected demographic clinical data prior...
Introduction The impact of the different ventilatory support modalities and timing intubation on longitudinal lung recovery trajectories in patients with severe COVID-19 is unknown. Methods A multicenter, prospective observational study conducted 52 Spanish intensive care units (ICUs) involving critically ill admitted between February 25th, 2020, to 28th, 2021. 1854 were followed after hospital discharge at 3, 6 12 months diffusing capacity (D LCO ) a chest imaging. Patients classified...
Abstract Background The relative contribution of the different components mechanical power to mortality is a subject debate and has not been studied in COVID-19. aim this study evaluate both total impact each on well-characterized cohort patients with COVID-19-induced acute respiratory failure undergoing invasive ventilation. This secondary analysis CIBERESUCICOVID project, multicenter observational including fifty Spanish intensive care units that included COVID-19 mechanically ventilated...