Sally Santisteve
A5052917154- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Thermal Regulation in Medicine
- Circadian rhythm and melatonin
- Family and Patient Care in Intensive Care Units
- Sleep and related disorders
- Extracellular vesicles in disease
- Biosimilars and Bioanalytical Methods
- Restless Legs Syndrome Research
- Peripheral Neuropathies and Disorders
- Public Health and Nutrition
- Pharmaceutical studies and practices
- Inflammation biomarkers and pathways
- Sepsis Diagnosis and Treatment
- Climate Change and Health Impacts
- Neurosurgical Procedures and Complications
- Congenital Diaphragmatic Hernia Studies
- COVID-19 and healthcare impacts
- Chronic Disease Management Strategies
- COVID-19 diagnosis using AI
- Infectious Encephalopathies and Encephalitis
Hospital Universitari Arnau de Vilanova
2020-2025
Biomedical Research Institute of Lleida
2020-2025
Centro de Investigación Biomédica en Red
2022-2024
Instituto de Salud Carlos III
2021-2024
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2021-2024
We evaluated whether the time between first respiratory support and intubation of patients receiving invasive mechanical ventilation (IMV) due to COVID-19 was associated with mortality or pulmonary sequelae.
OBJECTIVES: To investigate the sleep and circadian health of critical survivors 12 months after hospital discharge to evaluate a possible effect severity disease within this context. DESIGN: Observational, prospective study. SETTING: Single-center PATIENTS: Two hundred sixty patients admitted ICU due severe acute respiratory syndrome coronavirus 2 infection. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The cohort was composed 260 (69.2% males), with median (quartile 1–quartile 3) age...
To evaluate the sleep and circadian rest-activity pattern of critical COVID-19 survivors 3 months after hospital discharge.Observational, prospective study.Single-center study.One hundred seventy-two consecutive admitted to ICU with acute respiratory distress syndrome.Seven days actigraphy for assessment; validated questionnaires; tests at 3-month follow-up.The cohort included 172 patients, mostly males (67.4%) a median (25th-75th percentile) age 61.0 years (52.8-67.0 yr). The number was...
The long-term clinical management and evolution of a cohort critical COVID-19 survivors have not been described in detail. We report prospective observational study patients admitted to the ICU between March August 2020. follow-up post-COVID consultation comprised symptoms, pulmonary function tests, 6-minute walking test (6MWT), chest computed tomography (CT). Additionally, questionnaires evaluate prevalence post-COVID-19 syndrome were administered at 1 year. A total 181 during period. They...
There is a limited understanding of the pathophysiology postacute pulmonary sequelae in severe COVID-19. The aim current study was to define circulating microRNA (miRNA) profiles associated with function and radiologic features survivors SARS-CoV-2-induced ARDS. included patients who developed ARDS secondary SARS-CoV-2 infection (n = 167) group infected did not develop 33). Patients were evaluated 3 months after hospital discharge. follow-up complete evaluation chest computed tomography....
Abstract Background and Purpose The post‐acute sequelae of SARS‐CoV‐2 infection pose a significant global challenge, with nearly 50% critical COVID‐19 survivors manifesting persistent lung abnormalities. lack understanding about the molecular mechanisms effective treatments hampers their management. Here, we employed microRNA (miRNA) profiling to decipher systemic underpinnings pulmonary complications. Experimental Approach We conducted longitudinal investigation including 119 survivors. A...
Introduction The impact of the different ventilatory support modalities and timing intubation on longitudinal lung recovery trajectories in patients with severe COVID-19 is unknown. Methods A multicenter, prospective observational study conducted 52 Spanish intensive care units (ICUs) involving critically ill admitted between February 25th, 2020, to 28th, 2021. 1854 were followed after hospital discharge at 3, 6 12 months diffusing capacity (D LCO ) a chest imaging. Patients classified...
Abstract Background Survivors of critical illness endure long-lasting physical and mental challenges. Despite the persistence poor sleep quality in a considerable proportion patients at 12-month follow-up, studies with assessments exceeding this period are limited. We aimed to investigate trajectory over 24 months following illness. Methods Observational, prospective study. Patients diagnosed SARS-CoV-2 infection were recruited during intensive care unit stay. Evaluations (Pittsburgh Sleep...
Up to 80% of patients surviving acute respiratory distress syndrome (ARDS) secondary SARS-CoV-2 infection present persistent anomalies in pulmonary function after hospital discharge. There is a limited understanding the mechanistic pathways linked post-acute sequelae. To identify molecular underpinnings associated with severe lung diffusion involvement survivors SARS-CoV-2-induced ARDS. Survivors attended complete evaluation 3 months RNA sequencing (RNA-seq) was performed using Illumina...
<title>Abstract</title> Background COPD patients show higher mortality and worse prognosis in the acute phase of COVID-19, survivors may suffer persistent symptoms that could make them more vulnerable to exacerbations. Objectives We aimed evaluate impact COVID-19 on exacerbations, symptoms, quality life, mental health a cohort patients. Methods Retrospective case-control single-centre study including all from pulmonary consultation University Hospital Santa Maria (Lleida, Spain) surviving...
<b>Background:</b> Assessments to evaluate whether the effects of intensive care unit (ICU) on sleep and circadian health persist in long term are scarce. <b>Objective:</b> To critical survivors after a 12-month follow-up. <b>Methods:</b> Prospective, observational study. Critical patients due SARS-CoV-2 infection were recruited during ICU stay. Clinical evaluations including Pittsburgh Sleep Quality Index (PSQI) actigraphy (7 days) performed 3, 6, 12 months hospital discharge....