J.L. García Garmendia
A5038516819- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Nosocomial Infections in ICU
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Pneumonia and Respiratory Infections
- Meta-analysis and systematic reviews
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Tracheal and airway disorders
- Clinical Reasoning and Diagnostic Skills
- SARS-CoV-2 and COVID-19 Research
- Healthcare cost, quality, practices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Electrolyte and hormonal disorders
- Antifungal resistance and susceptibility
- Heart Failure Treatment and Management
- Hemodynamic Monitoring and Therapy
- Clinical Nutrition and Gastroenterology
- Respiratory viral infections research
- Emergency and Acute Care Studies
- Health Systems, Economic Evaluations, Quality of Life
Hospital San Juan de Dios
2022-2024
Vall d'Hebron Institut de Recerca
2022
Vall d'Hebron Hospital Universitari
2022
Hospital Universitario Virgen Macarena
2022
Hospital Del Mar
2022
Hospital San Juan de Dios
2022
Universitat de Lleida
2021
Hospital Universitario Virgen del Rocío
1996-2004
Consejería de Educación de la Junta de Castilla y León
2002
Sociedad Española de Cuidados Intensivos Pediátricos
2001
Objectives Our primary goal was to evaluate the impact on in-hospital mortality rate of adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort patients admitted intensive care unit (ICU) with sepsis. The therapy early (<3 days), 28-day, and 60-day rates also assessed. We determined risk factors inadequate therapy. Design Prospective study. Setting ICU tertiary hospital. Patients All meeting criteria sepsis at admission ICU. Interventions None....
We prospectively evaluated the efficacy and toxicity of intravenously administered colistin in 35 episodes ventilator-associated pneumonia (VAP) due to multidrug-resistant Acinetobacter baumannii. Microbiological diagnosis was performed with use quantitative culture. In 21 patients, were caused by a strain susceptible exclusively (the CO group) all treated this antimicrobial intravenously. 14 strains that remained imipenem imipenem-cilastatin IM group). Acute Physiology Chronic Health...
The objective of this study was to assess the cumulative incidence invasive candidiasis (IC) in intensive care units (ICUs) Europe. A multinational, multicenter, retrospective conducted 23 ICUs 9 European countries, representing first phase candidemia/intra-abdominal ICU project (EUCANDICU). During period, 570 episodes ICU-acquired IC were observed, with a 7.07 per 1000 admissions, important between-center variability. Separated, non-mutually exclusive incidences candidemia and IAC 5.52 1.84...
Our aims were to explore current intubation practices in Spanish ICUs determine the incidence and risk factors of peri-intubation complications (primary outcome measure: major adverse events), rate associated with first-pass success, their impact on mortality as well changes procedure observed COVID-19 pandemic.
The number of nosocomial infections caused by Acinetobacter baumannii has increased in recent years. During a 12-month study, there were 1.8 episodes A. Baumannii bacteremia per 1,000 adults admitted to hospital Seville, Spain. Seventy-nine patients included the study. occurred after mean (+/- SD) hospitalization 18 +/- 20 days. In all cases acquired nosocomially; 71% wee intensive care units. Ampicillin/ sulbactam was found be most active agent against baumannii. common source respiratory...
Nosocomial bacteremia caused by Acinetobacter baumannii (AB) is of increasing concern in critically ill patients, and the risk factors for this infection are not well established. An inception cohort study a 40-bed medical surgical intensive care unit (ICU) at single institution was conducted during 2-year period to determine AB nosocomial bacteremia. Risk related underlying diseases, clinical picture admission, those acquired stay ICU were recorded upon admission daily throughout stay. We...
Background The transfusion of erythrocytes that have been stored for long periods time can produce visceral ischemia and favor the acquisition postsurgical infections. To estimate role duration storage on morbidity in cardiac surgery, we performed an observational study. Methods All patients (n = 897) undergoing surgery during three consecutive years were included. Morbidity (main outcome measure) was evaluated by means four surrogate measures: stay intensive care unit longer than 4 days,...
To determine the attributable mortality and excess length of stay (LOS) associated with use inadequate empirical antimicrobial therapy in patients sepsis at admission to intensive care unit (ICU).A retrospective matched cohort study was performed using a prospectively collected database 40 bed general ICU university public hospital. Patients who received (exposed) were controls (unexposed) on basis origin sepsis, inflammatory response admission, surgical or medical status, hospital-...
The primary aim of our study was to investigate the association between intubation timing and hospital mortality in critically ill patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure. We also analysed both impact such throughout first four pandemic waves influence prior noninvasive support on outcomes.This is a secondary analysis multicentre, observational prospective cohort that included all consecutive undergoing invasive mechanical ventilation due COVID-19...
Although the prevalence of community-acquired respiratory bacterial coinfection upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been reported to be < 5%, almost three-quarters received antibiotics. We aim investigate whether procalcitonin (PCT) or C-reactive protein (CRP) could helpful biomarkers identify among COVID-19 pneumonia. carried out a multicentre, observational cohort study including consecutive admitted 55 Spanish intensive care units (ICUs). The...
To determine the impact of Acinetobacter baumannii (AB) acquisition in intensive care unit (ICU) patients on mortality and length stay (LOS).Pairwise matched 1:1 case-control study.Medical-surgical ICU a tertiary health institution.During 16 months, all admitted to were eligible. Case defined as every patient with an AB isolation 48 hrs after admission. Control retrospectively selected from without any isolation, according seven matching variables.Attributable excess LOS measured....
Abstract Background Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study investigate associations between mortality and variables measured during first three days ventilation with intubated at ICU admission. Methods Multicenter, observational, cohort includes consecutive admitted 44 Spanish ICUs February 25 July 31, 2020, who required intubation admission for more than days. We collected demographic clinical data prior...
Intra-abdominal infections represent the second most frequently acquired infection in intensive care unit (ICU), with mortality rates ranging from 20% to 50%. Candida spp. may be responsible for up 10-30% of cases. This study assesses risk factors development intra-abdominal candidiasis (IAC) among patients admitted ICU.We performed a case-control 26 European ICUs during period January 2015-December 2016. Patients at least 18 years old who developed an episode microbiologically documented...
The objective of this study was to evaluate the impact empirical therapy with fluconazole or an echinocandin on 30- and 90-day mortality in critically ill patients candidemia. outcome whom deescalated also assessed.Retrospective, observational multicenter study.Medical surgical ICUs nine Spanish hospitals.Adult (≥ 18 yr) episode Candida bloodstream infection during ICU admission from January 2011 April 2016.Patient characteristics, infection-related variables, therapeutic interventions,...