A5056637285- Influenza Virus Research Studies
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
- Data-Driven Disease Surveillance
- Herpesvirus Infections and Treatments
- Antibiotic Resistance in Bacteria
- Viral Infections and Outbreaks Research
- Nosocomial Infections in ICU
- Immunotherapy and Immune Responses
- Hepatitis B Virus Studies
- Bacterial Identification and Susceptibility Testing
- Misinformation and Its Impacts
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Antibiotics Pharmacokinetics and Efficacy
- Tuberculosis Research and Epidemiology
- Hepatitis C virus research
- Virology and Viral Diseases
- SARS-CoV-2 and COVID-19 Research
- Acne and Rosacea Treatments and Effects
Azienda Sanitaria Locale N. 2 Savonese
2024
Ospedale Santa Corona
2022
University of Genoa
2011-2021
University of Bari Aldo Moro
2021
Ospedale Policlinico San Martino
2012-2017
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2015
University of Yamanashi
2015
Fukuoka Prefecture Education Center
2015
University of Amsterdam
2015
University of Minho
2015
The objective of this study was to assess the cumulative incidence invasive candidiasis (IC) in intensive care units (ICUs) Europe. A multinational, multicenter, retrospective conducted 23 ICUs 9 European countries, representing first phase candidemia/intra-abdominal ICU project (EUCANDICU). During period, 570 episodes ICU-acquired IC were observed, with a 7.07 per 1000 admissions, important between-center variability. Separated, non-mutually exclusive incidences candidemia and IAC 5.52 1.84...
The 2014 Ebola epidemic in West Africa has attracted public interest worldwide, leading to millions of Ebola-related Internet searches being performed during the period epidemic. This study aimed evaluate and interpret Google search queries for terms related outbreak both at global level all countries where primary cases occurred. also endeavoured look correlation between number overall weekly web new Ebola.Google Trends (GT) was used explore activity Ebola. from 29 December 2013 14 June...
We aimed to describe the characteristics of patients with Staphylococcus aureus bacteremia and evaluate risk factors associated early (7-day) late (30-day) mortality. performed an observational study including all consecutive episodes diagnosed at two Italian university hospitals during 2010–2014. A total 337 were included. Mean age was 69 years (range, 57–78) 65% males. Methicillin-resistant S. (MRSA) identified in 132/337 (39%)cases. Overall 7- 30-day mortality 13% 26%, respectively. Early...
The recent spreading of Zika virus represents an emerging global health threat. As such, it is attracting public interest worldwide, generating a great amount related Internet searches and social media interactions. aim this research was to understand Zika-related digital behavior throughout the epidemic assess its consistence with real-world epidemiological data, using behavioral informatics analytics approach.In study, web-interest reaction recently occurred outbreaks Virus were analyzed...
Influenza vaccination is a fundamental tool for the prevention of influenza in healthcare settings and its administration to workers (HCWs) recommended more than 40 countries including United States America many European Union. Despite these recommendations, compliance HCWs largely inadequate Italy. Since 2005/06 season, comprehensive multifaceted intervention project aimed at increasing seasonal coverage rates among was performed IRCCS AOU San Martino IST teaching hospital Genoa, Italy,...
Objectives Notwithstanding decades of efforts to increase the uptake seasonal influenza (flu) vaccination among European healthcare workers (HCWs), immunisation rates are still unsatisfactory. In order understand reasons for low adherence flu vaccination, a study was carried out HCWs two organisations in Liguria, region northwest Italy. Methods A cross-sectional based on anonymous self-administered web questionnaires between October 2013 and February 2014. Through univariate multivariate...
Available evidence from observational studies and meta-analyses has highlighted an increased mortality in patients with carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infections (BSI) compared their carbapenem-susceptible (CSKP) counterparts, but the exact reasons for this outcome difference are still to be determined. We updated search of a previous meta-analysis through four databases up April 2018. A two-stage individual-patient data (IPD) was conducted, building adjusting...
Intra-abdominal infections represent the second most frequently acquired infection in intensive care unit (ICU), with mortality rates ranging from 20% to 50%. Candida spp. may be responsible for up 10-30% of cases. This study assesses risk factors development intra-abdominal candidiasis (IAC) among patients admitted ICU.We performed a case-control 26 European ICUs during period January 2015-December 2016. Patients at least 18 years old who developed an episode microbiologically documented...
Bloodstream infections (BSI) due to carbapenem-resistant (C-R) Klebsiella pneumoniae (Kp) are of global concern from both clinical and public health standpoints. This retrospective study aimed describe C-R Kp BSI epidemiology in a large teaching hospital northern Italy. Between 1 January 2007 31 December 2014, annual incidences carbapenem-susceptible (C-S) were calculated as the number events per 10,000 patient-days. A Chi square test for linear trend was used assess change incidence C-S...
Invasive fungal infections remain a leading cause of morbidity and mortality among liver transplant recipients (LTRs). In this patient population, invasive Candida (ICIs) account for the large majority cases. To date, only small studies case-series analysing clinical presentation risk factors in LTRs with ICIs are available.We performed retrospective multicenter multinational study 10 centers Europe Brazil. All consecutive developing during period January 2011 to December 2013 were included...
Herpes Zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), represent important public health issues because of their relevant burden among older adults. However, data on the epidemiology HZ PHN in Italy are very limited. A population-based study was performed by seeking for cases PHN, occurred period 2013-2015, clinical charts 56 General Practitioners working 4 Italian Regions (Liguria, Puglia, Toscana Veneto). The objective to estimate incidence proportion (at 1 3 mo from...
Vaccination against Hepatitis B Virus (HBV) became mandatory in Italy for all newborns and 12 years-old individuals the 1991. The immunogenicity of HBV vaccine effectiveness universal immunization strategy have been widely demonstrated. However need to assess antibody concentrations above well known serological correlate protection infection (≥10 mIU/mL), established immunized with a 3 doses vaccination course, is still recommended subjects exposed occupational risks different settings,...
In the last decade, carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become endemic in several countries, including Italy. present study, we assessed differences epidemiology, management, and mortality of CR-Kp bloodstream infection (BSI) three main adult acute-care hospitals metropolitan area Genoa, From January 2013 to December 2014, all patients with BSI were identified through computerized microbiology laboratory databases hospitals. The primary endpoints study incidence...
Post licensure surveillance of adverse events following immunization (AEFI) is a fundamental activity to improve safety and maintain public confidence in vaccines. Since 2011, the Liguria Region has been involved inter-regional project post-marketing AEFI, coordinated by Italian Medicine Agency Veneto region. The main objectives are: (1) coordinate activities 8 Regions included project; (2) encourage signal AEFI healthcare workers patients; (3) organize education addressed health care...
HBV surface antigen (HBsAg) variants may impair diagnosis or allow the virus to escape vaccine-induced immunity and their circulation in population can represent a Public Health threat. Their prevalence, however, is not yet completely established. Evidence indicates that amino acid substitutions within HBsAg lead conformational changes which mutated antibodies used screening tests. In such scenario, aim of this study was investigate prevalence S-Gene mutants by sequencing gene cohort...