A5100624934- Legionella and Acanthamoeba research
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Medical Device Sterilization and Disinfection
- Dental Research and COVID-19
- Diverse Scientific and Economic Studies
- Nosocomial Infections in ICU
- Infection Control in Healthcare
- Surgical site infection prevention
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Orthopedic Infections and Treatments
- Antifungal resistance and susceptibility
- Healthcare Facilities Design and Sustainability
- Water Treatment and Disinfection
- Total Knee Arthroplasty Outcomes
- Healthcare cost, quality, practices
- Antimicrobial Resistance in Staphylococcus
- Air Quality and Health Impacts
- Indoor Air Quality and Microbial Exposure
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial agents and applications
University of Genoa
2016-2025
Ente Ospedaliero Ospedali Galliera
2017-2024
Department of Medical Sciences
2013-2023
Isabela State University
2023
Universidade Federal de Pernambuco
2022
Universidade Estadual do Ceará
2022
Central Luzon State University
2018
Universidade Estadual de Campinas (UNICAMP)
2017
Istituto per il Lessico Intellettuale Europeo e la Storia delle Idee
2005-2016
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2005-2015
Implementation of environmental cleaning and disinfection has been shown to reduce the incidences healthcare-associated infections. The effect an enhanced strategy for terminal room disinfection, applying pulsed xenon-based ultraviolet light no-touch systems (PX-UVC) after current standard operating protocol (SOP) was evaluated. In a teaching hospital, effectiveness in reducing total bacterial count (TBC) eliminating high-concern microorganisms assessed on five high-touch surfaces different...
Pseudomonas aeruginosa is a Gram-negative pathogen that has become an important cause of infection in humans and can be associated with significant morbidity mortality. Severe infections usually affect immunocompromised patients or those chronic debilitating diseases. Its significance as exacerbated by its resistance to antibiotics, virulence factors ability adapt wide range environments. P. have multiple intrinsic acquired mechanisms resistance, frequently high rates various antimicrobial...
Even today, healthcare-associated infections (HCAIs) remain the most frequent and serious complications in healthcare, with a significant clinical economic impact. The authors of this manuscript address causes conditions that determine situation describe them comparison Grand Duchy Tuscany more than two centuries ago instructions were issued at time to contain typhus epidemic 1817, increase hospital sanitation, disinfect houses. Today, we know crucial element fight against is definition...
Objectives. To assess the degree of fungal contamination in hospital environments and to evaluate ability air conditioning systems reduce such contamination. Methods. We monitored airborne microbial concentrations various 10 hospitals equipped with conditioning. Sampling was performed a portable Surface Air System impactor replicate organism detection counting plates containing fungus-selective medium. The total concentration determined 72-120 hours after sampling. genera most involved...
In Italy, more than 3 million people annually sustain a domestic injury; the elderly experience it most. From healthcare perspective, falls are major clinical issue with an outgrowing socioeconomic burden. The aim of study was to evaluate epidemiology injurious in community dwelling population, admitted emergency room (ER) because injury, assess Seventy-four hospitalized patients among 227 were examined. Falls represented main cause admittance ER; average cost for fall-related...
Several studies have proposed that the microbiological quality of air in operating theatres be indirectly evaluated by means particle counting, a technique derived from industrial clean-room technology standards, using airborne concentration as an index microbial contamination. However, relationship between counting and sampling has rarely been demonstrated theatres. The aim present study was to determine whether could predict contamination theatre during 95 surgical arthroplasty procedures....
Legionella control still remains a critical issue in healthcare settings where the preferred approach to health risk assessment and management is develop water safety plan. We report experience of university hospital, plan has been applied since 2002, results obtained with application different methods for disinfecting hot distribution systems order provide guidance risk.The disinfection procedures included continuous chlorination chlorine dioxide (0.4-0.6 mg/L recirculation loops)...
Legionella is an intracellular microorganism living in natural and artificial aquatic environments. Although its transmission to humans linked the inhalation of contaminated aerosols, there no validated air sampling method for control prevention disease. The aim present study was provide more information on distribution spp. indoor environments determine whether same strains are isolated from water samples.Ten healthcare facilities located seven regions Italy were enrolled. serological...
Objective. Our aim was to evaluate the impact of aerators on water microbiological contamination in at-risk hospital departments, with a view quantifying possible risk patient exposure waterborne microorganisms. Design. We analyzed and chemical-physical characteristics hot cold some critical departments. Setting. Two hospitals northern Italy. Methods. took 304 samples over 1-year period, at 3-month intervals, from taps used by healthcare personnel for handwashing, surgical washing, washing...
Healthcare facilities (HF) represent an at-risk environment for legionellosis transmission occurring after inhalation of contaminated aerosols. In general, the control water is preferred to that air because, date, there are no standardized sampling protocols. Legionella contamination was investigated in bathrooms 11 HF by active (Surface Air System and Coriolis®μ) passive using settling plates. During 8-hour sampling, hot tap sampled three times. All samples were evaluated culture-based...
In the last decade, carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become endemic in several countries, including Italy. present study, we assessed differences epidemiology, management, and mortality of CR-Kp bloodstream infection (BSI) three main adult acute-care hospitals metropolitan area Genoa, From January 2013 to December 2014, all patients with BSI were identified through computerized microbiology laboratory databases hospitals. The primary endpoints study incidence...
Introduction: Dental Unit Waterlines (DUWLs) have shown to be a source of Legionella infection. We report the experience different dental healthcare settings where risk management plan was implemented. Materials and methods: In Hospital Odontostomatology Clinic (HOC) three Private Clinics (PDCs) housing 13 six units (DUs), respectively, an assessment checklist applied evaluate staff compliance with guideline recommendations. DUWLs microbial parameters were investigated before after...
COVID-19 respiratory failure is a life-threatening condition. Oxygenation targets were evaluated in non-ICU setting. In this retrospective, observational study, we enrolled all patients admitted to the University Hospital of Genoa, Italy, between 1 February and 31 May 2020 with an RT-PCR positive for SARS-CoV-2. PaO2, PaO2/FiO2 SatO2% collected analyzed at time 0 case admission, who required or not C-PAP (groups A B) categorized. Each measurement was correlated adverse outcome. total 483...