A5040265527- Vaccine Coverage and Hesitancy
- Virology and Viral Diseases
- Pneumonia and Respiratory Infections
- Immune responses and vaccinations
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Zoonotic diseases and public health
- Tuberculosis Research and Epidemiology
- Antibiotic Resistance in Bacteria
- Biosimilars and Bioanalytical Methods
- Hepatitis Viruses Studies and Epidemiology
- Erythropoietin and Anemia Treatment
- Renal Transplantation Outcomes and Treatments
- Respiratory viral infections research
- Hepatitis C virus research
- Herpesvirus Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Rabies epidemiology and control
- Bacterial Identification and Susceptibility Testing
- COVID-19 Digital Contact Tracing
- Syphilis Diagnosis and Treatment
- Infection Control in Healthcare
Azienda Sanitaria Locale Roma 3
2020-2022
Agenzia Regionale Sanitaria della Puglia
2022
Ministero della Salute
2011-2020
ASL Roma
2020
IQVIA (United States)
2012
Istituto Superiore di Sanità
2007
Sapienza University of Rome
2003-2004
Health Economics and Outcomes Research (United Kingdom)
1998
Italy introduced a national law extending the number of compulsory vaccines from four to 10 in July 2017. The implementation placed further burden on immunisation centres as they were required cover increased demand vaccination by parents unvaccinated children. Vaccine coverage (VC) estimated 6 months and 1 year later, at 24 30 (same birth cohort), had for all vaccines. At age, measles VC 87.3% 2016 91.8% 2017 94.1% age June 2018. In six 21 regions autonomous provinces, was >95%. Despite...
In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification response resulted in sustained...
Following the rapid increase of infections due to carbapenemase-producing Enterobacteriaceae (CPE) in Italy, national surveillance bloodstream (BSI) CPE (Klebsiella pneumoniae and Escherichia coli) was instituted 2013. All CPE-BSI cases reported years 2014-17 were analysed order investigate incidence rate (IR), trend, main individual characteristics enzymes involved resistance. Throughout this period, 7,632 (IR: 3.14/100,000 inhabitants) from all 21 regions autonomous provinces with an...
In Italy, national-level immunization polices are included in the National Immunization Prevention Plan (PNPV), whose latest edition - 2017-2019 PNPV was finally approved February 2017. Coverage rates a key measure of system performance; it can inform and support national regional polices' implementation monitoring, as well impact interventions aimed at increasing vaccine uptake.We collected, analysed critically interpreted 2000-2016 Italian infant coverage trends, by different vaccine,...
In Italy, the cohorts of women who were offered Human papillomavirus (HPV) vaccination in 2007/08 will reach age (25 years) for cervical cancer (CC) screening from 2017. The simultaneous shift cytology-based to HPV test-based gives opportunity unprecedented reorganisation CC prevention. ONS (National Screening Monitoring Centre) Directive and GISCi (Italian Group Cervical Screening) identified consensus conference as most suitable method addressing this topic. A summary recommendations is...
In June 2017, a decree-law to increase the number of mandatory vaccinations from 4 10 for minors up 16-years-old was issued in Italy. The vaccination coverage 2017 showed positive impact all vaccines, particularly measles, mumps and rubella vaccine at 91.6% year showing 4.4% compared with 2016 (87.2%). Continued monitoring is needed evaluate medium long-term effects law.
Abstract Background Identifying healthcare workers (HCW) who have less awareness and knowledge on antibiotic use resistance represents a challenge for public health, since it might help the development of novel educational training initiatives tailored specific subgroups professionals. This work aims to compare knowledge, attitudes behaviors across different groups Italian HCW. Methods We used data from multi-country multi-professional survey launched by European Centre Disease Prevention...
From 1 October 2010 to 31 December 2011, Italy experienced high measles burden with 5,568 cases (37.4% laboratory-confirmed) reported the enhanced surveillance system (cumulative incidence in 15-month reference period: 9.2/100,000 population). Adolescents and young adults were especially affected, median age of was 18 years. Most (95.8%) either unvaccinated or incompletely vaccinated. Complications for 20.3% cases, including 135 pneumonia, seven encephalitis one case Guillain–Barré syndrome....
In 2013/2014, Italy experienced one of the largest community-wide prolonged outbreaks hepatitis A virus (HAV) throughout country. The article provides a comprehensive description outbreak and investigation carried out by multidisciplinary National Task Force, in collaboration with regional local public health authorities. Control strategies food-borne HAV infection both human food sectors are also described.Enhanced epidemiological microbiological surveillance together monitoring trace-back...
We report an increase of serogroup C Neisseria meningitidis invasive meningococcal disease in Tuscany. From January 2015 to end February 2016, 43 cases were reported, among which 10 fatal, compared two caused by recorded 2014 and three 2013. No secondary occurred. Thirty–five strains belonged C:P1.5–1,10–8:F3–6:ST-11(cc11). Control measures have been adopted immunisation campaigns implemented. Studies on risk factors carriage are ongoing.
Herpes Zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), represent important public health issues because of their relevant burden among older adults. However, data on the epidemiology HZ PHN in Italy are very limited. A population-based study was performed by seeking for cases PHN, occurred period 2013-2015, clinical charts 56 General Practitioners working 4 Italian Regions (Liguria, Puglia, Toscana Veneto). The objective to estimate incidence proportion (at 1 3 mo from...
The Italian National Immunization Prevention Plan (PNPV) identifies vaccines actively offered free of charge to target populations within the Health Service. Despite this, childhood immunization coverage has been declining in Italy recent years. As a response, Parliament July 2017 approved law n. 119 extending mandatory from four ten, this stimulating lively debate at both scientific and policy level.We analysed critically interpreted 2000-2017 national trends, by different vaccine,...
In recent years various EU/EEA countries have experienced an influx of migrants from low and middle-income countries. 2018, the "Vaccine European New Integrated Collaboration Effort (VENICE)" survey group conducted a among 30 to investigate immunisation policies practices targeting irregular migrants, refugees asylum seekers (later called "migrants" in this report). Twenty-nine participated survey. Twenty-eight reported having national children/adolescent adult however vaccinations offered...
Incidence data on pertussis cases in Italy do not show resurgence as recently described other European countries. The aim of this study was to determine the seroprevalence IgG antibodies toxin (PT-IgG) selected adult age groups, who can serve a reservoir Bordetella and be responsible for onward transmission vulnerable infants. PT-IgG studied sera collected 2012-2013 three groups: 20-29 years 30-39 (reproductive age), ≥60 years. These were compared those from similar groups 1996-1997. More...
Outbreaks of measles continue to occur in Italy, as other European countries. We present here details cases reported through the Italian enhanced surveillance system from July 2009 September 2010. In total, 2,151 were reported, 42% (n=895) which laboratory confirmed. The median age was 18 years and 1,709 1,856 (92%) unvaccinated. Many with complications (n=305), including three encephalitis. A total 652 1,822 (36%) hospitalised. Molecular characterisation revealed circulation a limited...
In 2015 an increased incidence of invasive meningococcal disease due to serogroup-C (MenC) occurred in Tuscany, Italy. This led the Regional Health Authority Tuscany implement a reactive immunisation campaign and launch epidemiological field investigation aiming address targeted interventions. 2011-14, 10 MenC cases had been reported compared with 62 2015-16. The case fatality rate was 21% (n = 13) 51 (82.3%) were confirmed as C:P1.5-1,10-8:F3-6:ST-11(cc11). Overall, 17 clusters recognised....
Although most countries in the WHO European Region were verified 2017 as having interrupted endemic measles transmission, nine still endemic. Among these, Italy accounted for second highest number of cases reported Europe 2017. The elimination is at national level by each country’s National Verification Committee (NVC) through production an Annual Status Update (ASU). Since decentralization has led to inhomogeneous implementation immunization strategies among 21 administrative Regions,...
Despite extensive efforts to monitor the diffusion of COVID-19, actual wave infection is worldwide characterized by presence emerging SARS-CoV-2 variants. The present study aims describe yet undiscovered variants in Italy.Next Generation Sequencing was performed on 16 respiratory samples from occasionally employed within Bangladeshi community Ostia and Fiumicino towns. Computational strategy used identify all potential epitopes for reference mutated Spike proteins. A simulation proteasome...