A5101586872- Cervical Cancer and HPV Research
- Immunotherapy and Immune Responses
- Hepatitis B Virus Studies
- HIV Research and Treatment
- Immune Cell Function and Interaction
- Genital Health and Disease
- Hepatitis C virus research
- Cancer Immunotherapy and Biomarkers
- vaccines and immunoinformatics approaches
- Viral-associated cancers and disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- SARS-CoV-2 and COVID-19 Research
- Polyomavirus and related diseases
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related Molecular Pathways
- RNA Interference and Gene Delivery
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Bacteriophages and microbial interactions
- HIV/AIDS drug development and treatment
- Cancer Genomics and Diagnostics
- HIV/AIDS Research and Interventions
- Immune Response and Inflammation
- Virus-based gene therapy research
- Cytomegalovirus and herpesvirus research
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2015-2024
Gamalei Institute of Epidemiology and Microbiology
2022
Fondazione IRCCS Istituto Nazionale dei Tumori
2020
Victor (Japan)
2019
Michigan State University
2019
Multidisciplinary Digital Publishing Institute (Switzerland)
2019
Dartmouth College
2019
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2016
Molecular Oncology (United States)
2016
MRC Laboratory of Molecular Biology
2013-2015
We have recently developed a candidate human immunodeficiency virus type 1 (HIV-1) vaccine model based on HIV-1 Pr55(gag) virus-like particles (HIV-VLPs), produced in baculovirus expression system and presenting gp120 molecule from Ugandan isolate of clade A (HIV-VLP(A)s). The HIV-VLP(A)s show the induction BALB/c mice systemic mucosal neutralizing antibodies as well cytotoxic T lymphocytes, by intraperitoneal intranasal administration. In present article, effects baculovirus-expressed...
Recurrent somatic mutations in the promoter region of telomerase reverse transcriptase (TERT) gene and exon 3 CTNNB1 have been recognized as common events hepatocellular carcinoma (HCC) with variable frequencies depending on etiology geographical region. We analyzed TERT 122 cases hepatitis B (HBV) C (HCV) related HCCs, 7 cholangiocarcinoma (CC) hepatocholangiocarcinoma (HCC-CC) well autologous cirrhotic tissues. Overall, 50.4% 26% HCC 14.3% none CC HCC-CC were mutated 3, respectively. found...
We have recently shown extensive sequence and conformational homology between tumor-associated antigens (TAAs) derived from microorganisms (MoAs). The present study aimed to assess the breadth of T-cell recognition specific MoAs corresponding TAAs in healthy subjects (HS) patients with cancer (CP). A library > 100 peptide-MHC (pMHC) combinations was used generate DNA-barcode labelled multimers. Homologous peptides were selected Cancer Antigenic Peptide Database, as well...
Abstract Background: The aim of this multicentric study was to identify human papillomavirus (HPV) type distribution in invasive cervical cancer and high-grade intraepithelial neoplasia 2/3 (CIN2/3) Italy. Methods: Cases were sampled through the electronic databases at pathology units eight centers six regions from central southern HPV types detected paraffin-embedded tissue samples specimens amplification DNA with GP5+/GP6+ primers, followed by genotyping reverse line blot (RLB). Untyped...
Background The variability in the association of host innate immune response to Hepatitis C virus (HCV) infection requires ruling out possible role KIR and HLA genotypes HCV-related disorders: therefore, we therefore explored relationships between KIR/HLA chronic HCV (CHC) as they relate risk hepatocarcinoma (HCC) or lymphoproliferative disease progression. Methods Findings We analyzed data from 396 HCV-positive patients with CHC (n = 125), HCC (118), diseases (153), 501 HCV-negative...