A5016453181- Lymphoma Diagnosis and Treatment
- Hepatitis C virus research
- Chronic Lymphocytic Leukemia Research
- Viral-associated cancers and disorders
- Immune Cell Function and Interaction
- Helicobacter pylori-related gastroenterology studies
- Monoclonal and Polyclonal Antibodies Research
- Galectins and Cancer Biology
- Immunotherapy and Immune Responses
- Gastric Cancer Management and Outcomes
- Celiac Disease Research and Management
- T-cell and B-cell Immunology
- Liver Disease Diagnosis and Treatment
- Diabetes and associated disorders
- Systemic Lupus Erythematosus Research
- Hepatitis B Virus Studies
- Genetic factors in colorectal cancer
- Cancer-related gene regulation
- Cancer Immunotherapy and Biomarkers
- Esophageal Cancer Research and Treatment
- Parvovirus B19 Infection Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Wnt/β-catenin signaling in development and cancer
- Immunodeficiency and Autoimmune Disorders
- CNS Lymphoma Diagnosis and Treatment
Centro di Riferimento Oncologico
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2024
Regional Research Institute of Unani Medicine
2022
Central Research Institute
2022
Bryan College
2022
Molecular Oncology (United States)
2012
Regione Puglia
2011
University of Udine
2000-2007
National Cancer Institute
2006-2007
University of Bari Aldo Moro
2003-2006
Abstract Helicobacter pylori , a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to development genetically distinct H. subpopulations associated geographic origin host and differential disease risk. Here, we provide insights into population structure as part Genome Project ( Hp GP), multi-disciplinary initiative aimed at elucidating pathogenesis identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from...
Journal Article Human Herpesvirus 6: A Survey of Presence and Variant Distribution in Normal Peripheral Lymphocytes Lymphoproliferative Disorders Get access D. Di Luca, Luca Reprints or correspondence: Dr. Dario Institute Microbiology, Via Borsari 46, 44100 Ferrara, Italy. Search for other works by this author on: Oxford Academic PubMed Google Scholar R. Dolcetti, Dolcetti P. Mirandola, Mirandola V. De Re, Re Secchiero, Secchiero A. Carbone, Carbone M. Boiocchi, Boiocchi E. Cassai The...
Objective Type II mixed cryoglobulinemia (type MC) is often characterized by features of indolent B cell lymphoma (IBCL) found on pathologic examination bone marrow, whereas the clinical evidence does not indicate a neoplastic disorder. To better address issue malignant versus nonmalignant marrow lymphoproliferation underlying type MC, molecular analyses clonality were performed in present study, conjunction with and characterization. Methods Polymerase chain reaction DNA amplification...
Type II mixed cryoglobulinemia (MC) is a systemic vasculitis characterized by the presence in serum of monoclonal cryoprecipitable IgM with rheumatoid factor (RF) activity. Hepatitis C virus (HCV) has been recognized as its major etiologic factor. Because MC frequently evolves into overt B-cell non-Hodgkin's lymphoma (NHL), chronic HCV infection hypothesized to lead both benign and malignant lymphoproliferative disease. In this study, we investigated mutations V(H) V(K) genes clone...
Sjögren's syndrome (SS) represents a pathological model of the evolution from polyclonal B lymphocyte activation to oligoclonal / monoclonal cell expansion, which may culminate in development malignant lymphoproliferative disease. The different phases this process are usually marked by appearance antigen-driven activated clones, commonly IgM-positiveand with rheumatoid factor (RF) activity. However, agent(s) able trigger proliferation is still unknown. A similar pathogenetic mechanism exist...
Background The variability in the association of host innate immune response to Hepatitis C virus (HCV) infection requires ruling out possible role KIR and HLA genotypes HCV-related disorders: therefore, we therefore explored relationships between KIR/HLA chronic HCV (CHC) as they relate risk hepatocarcinoma (HCC) or lymphoproliferative disease progression. Methods Findings We analyzed data from 396 HCV-positive patients with CHC (n = 125), HCC (118), diseases (153), 501 HCV-negative...
Epidermal growth factor receptor (EGFR) and its ligand heparin-binding EGF-like (HB-EGF) sustain endothelial cell proliferation angiogenesis in solid tumors, but little is known about the role of HB-EGF-EGFR signaling bone marrow multiple myeloma (MM) progression. We found that cells from patients with MM express high levels EGFR HB-EGF, compared monoclonal gammopathy undetermined significance, overexpressed HB-EGF stimulates expression an autocrine loop. also parallel plasma number, a...