A5025918771- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Toxoplasma gondii Research Studies
- Psidium guajava Extracts and Applications
- Mycobacterium research and diagnosis
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Ethnobotanical and Medicinal Plants Studies
- Pharmacological Effects of Natural Compounds
- Gastric Cancer Management and Outcomes
- Food Chemistry and Fat Analysis
- Gastrointestinal motility and disorders
- Ginger and Zingiberaceae research
- African Botany and Ecology Studies
- Veterinary medicine and infectious diseases
- Antibiotic Resistance in Bacteria
- Banana Cultivation and Research
- Microbial Metabolites in Food Biotechnology
- Galectins and Cancer Biology
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Phytochemistry and biological activities of Ficus species
- Phytochemistry and Bioactive Compounds
Université de Dschang
2011-2024
Université de Yaoundé I
2022-2024
Helicobacter pylori is a Gram negative bacterium that colonizes the stomach of approximately two-thirds human population and it involved in pathogenesis gastroduodenal diseases. This study sought to determine potential risk factors associated with seroprevalence H. among dyspepsia patients Cameroon for better management disease. The was carried out from August December 2014 at Laquintinie Hospital District Bonassama Douala metropolis. 205 (127 women 78 men; mean age, 53.79 ± 11.11 years;...
Abstract Helicobacter pylori , a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to development genetically distinct H. subpopulations associated geographic origin host and differential disease risk. Here, we provide insights into population structure as part Genome Project ( Hp GP), multi-disciplinary initiative aimed at elucidating pathogenesis identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from...
Bryophyllum pinnatum (Lam.) Kurz (Crassulaceae) is a plant known for its antiulcer properties.This study evaluates the anti-Helicobacter pylori activity of pinnutum methanol extract with mouse model and antioxidant properties.Dried leaves were extracted ethyl acetate. Broth microdilution method was used to evaluate samples in vitro. Swiss mice inoculated suspension Helicobacter divided into control group four others that received 125, 250, 500 mg/kg or ciprofloxacin (500 mg/kg),...
Abstract Background Antibiotic resistance is a leading cause of treatment failure in Helicobacter pylori infection. In Africa, there are very little data concerning the susceptibility isolates to antibiotics. The purpose this study was evaluate prevalence strains circulating Cameroon, and assess overexpression efflux pump as possible multi-drug mechanisms. Methods A total 140 H. were recovered from gastric biopsies dyspeptic patients two reference hospitals Cameroon analyzed for their...
Abstract Diabetic mellitus patients are usually prone to chronic infections. However, there have been contradictory reports about the association between H. pylori infection and type II diabetes. The present study is aimed at evaluating prevalence of Helicobacter among 2 dyspeptic diabetic in littoral region Cameroon. This cross sectional comprised 93 112 non-diabetic attending Gastroenterology Department two reference hospitals Douala-Cameroon. was approved by local Ethical Committee...
Context: Peptic ulcer is one of the most common diseases affecting mankind. Although there are many products used for its treatment, these produce severe adverse reactions requiring search novel compounds. Some Afromomum species traditionally to cure acute gastritis.Objective: To evaluate antiulcer activity methanol extract Aframomum pruinosum Gagnepain (Zingiberaceae) seeds against two major etiologic agents peptic disease; Helicobacter pylori and non-steroidal anti-inflammatory...
This study was performed to evaluate the antimicrobial activities of extracts Bidens pilosa, Galinsoga ciliata, and Eryngium foetidum against 6 clinical strains Helicobacter pylori in vitro vivo . Broth microdilution method used In , Swiss mice were inoculated with H divided into 5 groups; control group received vehicle four others 125, 250, 500 mg/kg methanol extract ciprofloxacin (500 mg/kg) for 7 days, respectively. colonization number colonies gastric biopsies culture assessed on days 1...
The present study was designated to evaluated the antimicrobial activities of methanol, ethanol, hexane, ethyl acetate, aqueous, mixture methanol/water and ethanol/water extracts Pentadiplandra brazzeana, Erythrina sigmoïdea, Petersianthus macrocarpus, Clerodendrum umbellatum , Sida acuta Eleusine indica Bridelia micrantha Musanga cecropioides which are plants used as traditional folk medicine in Cameroon for treatment different infections disorders gastrointestinal disorders. against 17...
The present study was designed to evaluate the inhibitory effect of lactic acid bacteria (LAB) isolates from fermented cocoa juice and their cell-free culture supernatants (CFS) against Helicobacter pylori strains potential as good probiotic. Isolation performed by subculture sample on MRS agar. Morphological characteristics, Gram staining catalase reaction were used identify isolates. antagonistic activity LAB tested using agar spot-on-lawn method CFS well diffusion assay. Acid tolerance...
Abstract Background and Aim There have been contradictory reports about the association between Helicobacter pylori infection iron deficiency anemia (IDA). Based on high frequency of H. in Cameroon, we evaluated as cause anemia, IDA among dyspeptic patients Cameroon. Methods This cross‐sectional study enrolled 842 (472 women 370 men) two reference hospitals Douala‐Cameroon. Each participant gave a written consent, was approved by National Ethical Committee. Erythroid‐related indices markers...
Background: Helicobacter pylori infection is the most well-known risk factor for gastric mucosa abnormalities. However, some geographic regions with persistent high H. rates do not suffer from lesions incidence. The aim of study was to establish relationship between and pathological features in Cameroon. Methods: We performed a retrospective study, collecting data University Teaching Hospital Cameroon Pasteur institute on 1290 patients (mean age 46.31 ± 16.45 years, sex ratio 1.19:1) whom...
Abstract Background and Aim There is an intimate relationship between oxidative stress inflammation. Helicobacter pylori (H. pylori) infection leads to gastritis in almost all the hosts. So, we hypothesize that H. may be described as accumulation of continuous damage. Methods The study was conducted from October 2020 2021 at three reference health facilities Cameroon . A total 266 participants (131 males 135 females) ranging 15 88 years old with 48.28 ± 17.29 mean age were enrolled. Each...
Abstract Background and Aim Helicobacter pylori represents the major pathogen in pathophysiology of diverse gastrointestinal conditions. This study sought to determine endoscopic aspect gastric mucosa relation H. infection Cameroon. Methods was conducted three reference health facilities Cameroon from October 2020 2022. The enrolled 494 consecutive volunteer dyspeptic patients attending gastroenterology department selected facilities. A description all participants performed during endoscopy...
The present study was designated to evaluated the antimicrobial activities of methanol and ethyl acetate extracts Carcia arereh, Nelsonia canescens, Ficus thonningu, Bryophillum pinnatum, Cyclosorus striatus, Euphorbia cordifolia, hirta, Erygium foetidum Mimosa pudica. selected plants species are used as traditional folk medicine in Cameroon for treatment various diseases. Thiazolyl blue tetrazolium bromide colorimetric assay evaluate activity against 16 microbial species. Preliminary...
Background: Vertical transmission is an important route of for hepatitis B virus infection. Despite the introduction HBV vaccine in extended immunization program 2005, Cameroon has remained a hyper-endemic area. The aim this study was to determine seroprevalence Virus among antenatal clinic attenders Penka-Michel-Cameroon, and identify potential risk factors associated with infection better prevention disease.
 Study Design: case control conducted four reference hospitals Penka-Michel,...
Abstract Background : In Cameroon, studies on the prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (E-ESBLs) and carbapenemase-producing (CPE) among HIV infected individuals has not been investigated despite progressively risen infection. The present study is intended determinate magnitude ESBL-E CPE carriage HIV-infected individuals. Methods Accordingly, 152 urine, 29 stool, 8 blood, 105 vaginal exudates 14 wound swab sample were collected from 204 negative 104...
Ethyl acetate(EA) extract of the stem bark Cylicodiscus gabunensis (CG) and methanol(M) fruit-rinds Picralima nitida (PN) were analysed phytochemically evaluated for their antimicrobial activity against 17 pathogenic species isolated from patient: Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, flexneri, Morganella morganii, Proteus vulgaris, mirabilis, Salmonella thyphi, Citrobacter freundii, Enterobacter cloacae, agglomerans, Staphylococcus aureus, Streptococcus feacalis,...