A5052127281- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Virology and Viral Diseases
- COVID-19 Clinical Research Studies
- Mosquito-borne diseases and control
- COVID-19 and healthcare impacts
- COVID-19 Pandemic Impacts
- Pneumonia and Respiratory Infections
- Viral Infections and Vectors
- Data-Driven Disease Surveillance
- Bacterial Infections and Vaccines
- Herpesvirus Infections and Treatments
- Legionella and Acanthamoeba research
- SARS-CoV-2 detection and testing
- Zoonotic diseases and public health
- Gastric Cancer Management and Outcomes
- Malaria Research and Control
- Immune responses and vaccinations
- Viral gastroenteritis research and epidemiology
- Climate Change and Health Impacts
- Long-Term Effects of COVID-19
- Hepatitis Viruses Studies and Epidemiology
Istituto Superiore di Sanità
2016-2025
St Vincent's Hospital
2024
Ministry of Health
2016-2023
National Institute of Statistics
2023
National Institute of Health
2017-2022
European Centre for Disease Prevention and Control
2020-2021
Fondazione Bruno Kessler
2020
Indiana University Bloomington
2020
Northeastern University
2020
Hospital Clínico Universitario de Valladolid
2017
In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020. We detail first cases. As at 21 February, nine countries reported 47 Among 38 cases studied, were linked to two clusters in Germany and France, 14 infected China. Median case age 42 years; 25 male. Late detection of clusters’ index delayed isolation further local 5 March, there 4,250
Results from a European multicentre case-control study reported by Marta Valenciano and colleagues suggest good protection the pandemic monovalent H1N1 vaccine against pH1N1 no effect of 2009–2010 seasonal influenza on H1N1.
We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant reported by seven European countries. COVID-19 with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0–2.9; B.1.351: 3.6, CI: 2.1–6.2; P.1: 2.6, 1.4–4.8) B.1.1.7/SGTF also intensive care admission 2.3, 1.4–3.5; 2.2, 1.7–2.8).
OBJECTIVES: To describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) pediatric patients aged <18 years in Italy. METHODS: Data from national case-based surveillance system confirmed COVID-19 infections until May 8, 2020, were analyzed. Demographic subjects summarized by age groups (0–1, 2–6, 7–12, 13–18 years), risk factors for severity evaluated using a multilevel (clustered region) multivariable logistic regression model. Furthermore, comparison...
Background On 20 February 2020, a locally acquired coronavirus disease (COVID-19) case was detected in Lombardy, Italy. This the first signal of ongoing transmission severe acute respiratory syndrome 2 (SARS-CoV-2) country. The number cases Italy increased rapidly and country became Europe to experience SARS-CoV-2 outbreak. Aim Our aim describe epidemiology dynamics COVID-19 amid control measures. Methods We analysed all RT-PCR-confirmed reported national integrated surveillance system until...
Abstract Background Aim of the present study is to describe characteristics COVID-19-related deaths and compare clinical phenotype course occurring in adults (<65 years) older (≥65 years). Method Medical charts 3,032 patients dying with COVID-19 Italy (368 aged < 65 years 2,664 ≥65 were revised extract information on demographics, preexisting comorbidities, in-hospital complications leading death. Results Older presented a higher number comorbidities compared those <65...
We describe the epidemiological characteristics, pattern of circulation, and geographical distribution influenza B viruses its lineages using data from Global Influenza Study. included over 1.8 million cases occurred in thirty-one countries during 2000–2018. calculated proportion caused by lineages; determined timing A epidemics; compared age B/Victoria B/Yamagata cases; evaluated frequency lineage-level mismatch for trivalent vaccine. The median virus was 23.4%, with a tendency (borderline...
To estimate the effectiveness of mRNA vaccines against SARS-CoV-2 infection and severe covid-19 at different time after vaccination.
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Since the 2008/9 influenza season, I-MOVE multicentre case–control study measures vaccine effectiveness (VE) against medically-attended influenza-like-illness (ILI) laboratory confirmed as influenza. In 2011/12, European studies reported a decline in VE A(H3N2) within season. Using combined data from 2010/11 to 2014/15 we studied effects of time since vaccination on type/subtype-specific VE. We modelled by using restricted cubic spline, controlling for potential confounders (age, sex, onset,...
SUMMARY Background In February 2020, a locally-acquired COVID-19 case was detected in Lombardia, Italy. This the first signal of ongoing transmission SARS-CoV-2 country. The outbreak rapidly escalated to national level epidemic, amid WHO declaration pandemic. Methods We analysed data from case-based integrated surveillance system all RT-PCR confirmed infections as March 24 th collected Italian regions and autonomous provinces. Here we provide descriptive epidemiological summary on 62,843...
We report an ongoing measles outbreak in Italy, with over 4,400 cases reported 20 Regions from January to August 2017. Median age was 27 years, 88% of the were unvaccinated. The highest incidence infants below one year and 7% occurred among healthcare workers. Three deaths two encephalitis reported. Wide immunity gaps nosocomial transmission are major challenges elimination Italy.
Abstract Background Standardized mortality surveillance data, capable of detecting variations in total at population level and not only among the infected, provide an unbiased insight into impact epidemics, like COVID-19 (Coronavirus disease). We analysed temporal trend excess deaths positive cases SARS-CoV-2 by geographical area (north centre-south), age sex, taking account deficit previous months. Methods Data from Italian rapid system was used to quantify during epidemic, estimate months...
SARS-CoV-2 infection is heterogeneous in clinical presentation and disease evolution. To investigate whether immune response to the virus can be influenced by genetic factors, we compared HLA AB0 frequencies organ transplant recipients waitlisted patients according presence or absence of infection.A retrospective analysis was performed on an Italian cohort composed transplanted a January 2002 March 2020 time frame. Data from this were merged with registry COVID+ subjects, evaluating status...
Several species of protozoa cause acute or chronic gastroenteritis in humans, worldwide. The burden disease is particularly high among children living developing areas the world, where transmission favored by lower hygienic standards and scarce availability safe water. However, asymptomatic infection polyparasitism are also commonly observed poor settings. Here, we investigated prevalence intestinal two small fishing villages, Porto Said (PS) Santa Maria da Serra (SM), situated along river...
In Italy a national Plan for the surveillance of imported and autochthonous human vector-borne diseases (chikungunya, dengue, Zika virus disease West Nile (WNV) disease) that integrates veterinary (animals vectors) surveillance, is issued revised annually according with observed epidemiological changes. Here we describe results WNV integrated systems in from 2008 to 2015. A real time data exchange protocol place between rapidly identify occurrence animal cases define update map affected...
Significance We use a mathematical model to evaluate the Italian exit strategy after lockdown imposed against COVID-19 epidemics, comparing it number of alternative scenarios. highlight that successful reopening requires two critical conditions: low value reproduction and incidence infection. The first is needed allow some margin for expansion lifting restrictions; second because level will be maintained approximately constant has grown values close one. Furthermore, we suggest that, even...
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown post-lockdown periods using a retrospective cohort study with 38,534,169 citizens 222,875 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density region of residence were conducted evaluate area-level incidence, case-hospitalisation rate case-fatality. During post-lockdown, but not higher incidence cases observed most...
On March 11, 2020, Italy imposed a national lockdown to curtail the spread of severe acute respiratory syndrome coronavirus 2. We estimate that, 14 days after lockdown, net reproduction number had dropped below 1 and remained stable at »0.76 (95% CI 0.67-0.85) in all regions for >3 following weeks.
COVID-19 dramatically influenced mortality worldwide, in Italy as well, the first European country to experience Sars-Cov2 epidemic. Many countries reported a two-wave pattern of deaths; however, studies comparing two waves are limited. The objective study was compare all-cause excess between that occurred during year 2020 using nationwide data. All-cause mortalities were estimated negative binomial models with time modeled by quadratic splines. also applied estimate deaths “not directly...
Abstract To counter the second COVID-19 wave in autumn 2020, Italian government introduced a system of physical distancing measures organized progressively restrictive tiers (coded as yellow, orange, and red) imposed on regional basis according to real-time epidemiological risk assessments. We leverage data from integrated surveillance publicly available mobility evaluate impact three-tiered restriction human activities, SARS-CoV-2 transmissibility hospitalization burden Italy. The...