A5088172137- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Virology and Viral Diseases
- COVID-19 and healthcare impacts
- Mosquito-borne diseases and control
- COVID-19 Pandemic Impacts
- Viral Infections and Vectors
- Data-Driven Disease Surveillance
- Zoonotic diseases and public health
- Migration, Health and Trauma
- Immune responses and vaccinations
- Viral gastroenteritis research and epidemiology
- Influenza Virus Research Studies
- Vector-borne infectious diseases
- Insect and Pesticide Research
- Travel-related health issues
- Hepatitis Viruses Studies and Epidemiology
- Syphilis Diagnosis and Treatment
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- COVID-19 Impact on Reproduction
- Animal Virus Infections Studies
- Malaria Research and Control
Istituto Superiore di Sanità
2016-2025
Ministry of Health
2023
Istituto Nazionale di Statistica
2023
University of Rome Tor Vergata
2023
European Centre for Disease Prevention and Control
2016-2022
National Institute of Health
2020
Ministry of Health
2020
Fondazione Bruno Kessler
2020
Indiana University Bloomington
2020
Northeastern University
2020
OBJECTIVES: To describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) pediatric patients aged <18 years in Italy. METHODS: Data from national case-based surveillance system confirmed COVID-19 infections until May 8, 2020, were analyzed. Demographic subjects summarized by age groups (0–1, 2–6, 7–12, 13–18 years), risk factors for severity evaluated using a multilevel (clustered region) multivariable logistic regression model. Furthermore, comparison...
An autochthonous chikungunya outbreak is ongoing near Anzio, a coastal town in the province of Rome. The virus isolated from one patient and mosquitoes lacks A226V mutation belongs to an East Central South African strain. As 20 September, 86 cases are laboratory-confirmed. proximity capital, its late summer occurrence, diagnostic delays, favouring transmission. Vector control, enhanced surveillance restricted blood donations being implemented affected areas.
Background On 20 February 2020, a locally acquired coronavirus disease (COVID-19) case was detected in Lombardy, Italy. This the first signal of ongoing transmission severe acute respiratory syndrome 2 (SARS-CoV-2) country. The number cases Italy increased rapidly and country became Europe to experience SARS-CoV-2 outbreak. Aim Our aim describe epidemiology dynamics COVID-19 amid control measures. Methods We analysed all RT-PCR-confirmed reported national integrated surveillance system until...
Abstract Background Aim of the present study is to describe characteristics COVID-19-related deaths and compare clinical phenotype course occurring in adults (<65 years) older (≥65 years). Method Medical charts 3,032 patients dying with COVID-19 Italy (368 aged < 65 years 2,664 ≥65 were revised extract information on demographics, preexisting comorbidities, in-hospital complications leading death. Results Older presented a higher number comorbidities compared those <65...
To estimate the effectiveness of mRNA vaccines against SARS-CoV-2 infection and severe covid-19 at different time after vaccination.
Between 1 June 2016 and 31 May 2017, 17 European Union (EU) Economic Area countries reported 4,096 cases associated with a multi-country hepatitis A (HA) outbreak. Molecular analysis identified three co-circulating virus (HAV) strains of genotype IA: VRD_521_2016, V16–25801 RIVM-HAV16–090. We categorised as confirmed, probable or possible, according to the EU outbreak case definitions. Confirmed were infected one strains. investigated characteristics strain-specific risk factors for...
SUMMARY Background In February 2020, a locally-acquired COVID-19 case was detected in Lombardia, Italy. This the first signal of ongoing transmission SARS-CoV-2 country. The outbreak rapidly escalated to national level epidemic, amid WHO declaration pandemic. Methods We analysed data from case-based integrated surveillance system all RT-PCR confirmed infections as March 24 th collected Italian regions and autonomous provinces. Here we provide descriptive epidemiological summary on 62,843...
We report an ongoing measles outbreak in Italy, with over 4,400 cases reported 20 Regions from January to August 2017. Median age was 27 years, 88% of the were unvaccinated. The highest incidence infants below one year and 7% occurred among healthcare workers. Three deaths two encephalitis reported. Wide immunity gaps nosocomial transmission are major challenges elimination Italy.
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown post-lockdown periods using a retrospective cohort study with 38,534,169 citizens 222,875 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density region of residence were conducted evaluate area-level incidence, case-hospitalisation rate case-fatality. During post-lockdown, but not higher incidence cases observed most...
On March 11, 2020, Italy imposed a national lockdown to curtail the spread of severe acute respiratory syndrome coronavirus 2. We estimate that, 14 days after lockdown, net reproduction number had dropped below 1 and remained stable at »0.76 (95% CI 0.67-0.85) in all regions for >3 following weeks.
Since February 21 2020, when the Italian National Institute of Health (Istituto Superiore di Sanità-ISS) reported first autochthonous case infection, a dedicated surveillance system for SARS-CoV-2-positive (COVID+) cases has been created in Italy. These data were cross-referenced with those inside Information Transplant System order to assess cumulative incidence (CI) and outcome SARS-COV-2 infection solid organ transplant recipients (SOTRs) who are assumed be most at risk. We compared our...
Abstract To counter the second COVID-19 wave in autumn 2020, Italian government introduced a system of physical distancing measures organized progressively restrictive tiers (coded as yellow, orange, and red) imposed on regional basis according to real-time epidemiological risk assessments. We leverage data from integrated surveillance publicly available mobility evaluate impact three-tiered restriction human activities, SARS-CoV-2 transmissibility hospitalization burden Italy. The...
During 2022, Omicron became the dominant SARS-CoV-2 variant in Europe. This study aims to assess impact of such on severe disease from compared with Delta Italy.Using surveillance data, we assessed risk developing COVID-19 infection individuals aged ≥12 years using a multilevel negative binomial model adjusting for sex, age, vaccination status, occupation, previous infection, weekly incidence, and geographical area. We also analyzed interaction between sequenced variant, status.We included...
Effectiveness against severe COVID-19 of a second booster dose the bivalent (original/BA.4-5) mRNA vaccine 7-90 days post-administration, relative to first an received ≥ 120 earlier, was ca 60% both in persons 60 years never infected and those > 6 months before. Relative effectiveness 4-6 earlier indicated no significant additional protection (10%; 95% CI: -44 44). A vaccination after latest infection may be warranted.
International literature suggests that disadvantaged groups are at higher risk of morbidity and mortality from SARS-CoV-2 infection due to poorer living/working conditions barriers healthcare access. Yet, date, there is no evidence this disproportionate impact on non-national individuals, including economic migrants, short-term travellers refugees.We analyzed data the Italian surveillance system all COVID-19 laboratory-confirmed cases tested positive beginning outbreak (20th February) 19th...
BackgroundDengue is a disease with major impacts on public health in tropical and subtropical countries. In Europe, the past decade, few autochthonous outbreaks were described.AimWe aimed to identify factors associated frequency of dengue virus infection among European travellers at assessing how surveillance data could support preparedness against within Europe.MethodsWe performed descriptive analysis travel-related cases reported by countries from 2015 through 2019. Using flight passenger...
As in 2018, when a large West Nile virus (WNV) epidemic occurred, the 2022 vector season Italy was marked by an early onset of WNV circulation mosquitoes and birds. Human infections were limited until July, we observed rapid increase number cases. We describe epidemiology human animal surveillance for compare more consolidated data June July with same period 2018.
During predominant circulation of SARS-CoV-2 Omicron XBB.1.5 and other XBB sublineages (April-June 2023), we found that a second or third booster Comirnaty bivalent Original/Omicron BA.4-5 mRNA vaccine, versus first received at least 120 days earlier, was effective in preventing severe COVID-19 for more than 6 months post-administration persons 60 years above. In view autumn 2023 vaccination campaigns, use vaccines might be warranted until monovalent targeting XBB.1 become available.
Between August and 28 October 2024, 199 autochthonous cases of dengue virus serotype 2 were notified in the city Fano, central Italy. We describe ongoing epidemiological microbiological investigation public health measures implemented to contain outbreak. The high transmissibility extension outbreak suggest that should be expected temperate regions during favourable seasons, highlighting need for heightened awareness among healthcare providers ensure timely detection response.
We explored the risk factors associated with SARS-CoV-2 reinfections in Italy between August 2021 and March 2022. Regardless of prevalent virus variant, being unvaccinated was most relevant factor for reinfection. The reinfection increased almost 18-fold following emergence Omicron variant compared Delta. A severe first infection age over 60 years were significant
BackgroundSeveral SARS-CoV-2 variants of concern (VOC) have emerged through 2020 and 2021. There is need for tools to estimate the relative transmissibility emerging with respect circulating strains.AimWe aimed assess prevalence co-circulating VOC in Italy their transmissibility.MethodsWe conducted two genomic surveillance surveys on 18 February March 2021 across whole Italian territory covering 3,243 clinical samples developed a mathematical model that describes dynamics strains.ResultsThe...
Abstract Background The difficulty in identifying SARS‐CoV‐2 infections has not only been the major obstacle to control COVID‐19 pandemic but also quantify changes proportion of resulting hospitalization, intensive care unit (ICU) admission, or death. Methods We developed a model transmission and vaccination informed by official estimates time‐varying reproduction number estimate that occurred Italy between February 2020 2022. Model outcomes were compared with Italian National surveillance...