A5061762387- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Vaccine Coverage and Hesitancy
- Data-Driven Disease Surveillance
- Influenza Virus Research Studies
- COVID-19 Pandemic Impacts
- Literacy and Educational Practices
- Spanish Literature and Culture Studies
- Literature, Culture, and Aesthetics
- Health disparities and outcomes
- Mosquito-borne diseases and control
- COVID-19 Digital Contact Tracing
- Global Health Care Issues
- Libraries, Manuscripts, and Books
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Educational theories and practices
- Migration, Health and Trauma
- History of Education in Spain
- Chronic Disease Management Strategies
- COVID-19 and Mental Health
- COVID-19 Impact on Reproduction
- Employment and Welfare Studies
Istituto Superiore di Sanità
2020-2025
Institute of Studies for the Integration of Systems
2024
Fondazione Bruno Kessler
2020-2023
Kessler Foundation
2023
University of Rome Tor Vergata
2023
European Centre for Disease Prevention and Control
2020-2022
National Institute of Health
2020
Indiana University Bloomington
2020
Northeastern University
2020
Public Health England
2020
OBJECTIVES: To describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) pediatric patients aged <18 years in Italy. METHODS: Data from national case-based surveillance system confirmed COVID-19 infections until May 8, 2020, were analyzed. Demographic subjects summarized by age groups (0–1, 2–6, 7–12, 13–18 years), risk factors for severity evaluated using a multilevel (clustered region) multivariable logistic regression model. Furthermore, comparison...
Background On 20 February 2020, a locally acquired coronavirus disease (COVID-19) case was detected in Lombardy, Italy. This the first signal of ongoing transmission severe acute respiratory syndrome 2 (SARS-CoV-2) country. The number cases Italy increased rapidly and country became Europe to experience SARS-CoV-2 outbreak. Aim Our aim describe epidemiology dynamics COVID-19 amid control measures. Methods We analysed all RT-PCR-confirmed reported national integrated surveillance system until...
Abstract Background Aim of the present study is to describe characteristics COVID-19-related deaths and compare clinical phenotype course occurring in adults (<65 years) older (≥65 years). Method Medical charts 3,032 patients dying with COVID-19 Italy (368 aged < 65 years 2,664 ≥65 were revised extract information on demographics, preexisting comorbidities, in-hospital complications leading death. Results Older presented a higher number comorbidities compared those <65...
To estimate the effectiveness of mRNA vaccines against SARS-CoV-2 infection and severe covid-19 at different time after vaccination.
Abstract The 2030 Agenda for the Sustainable Development Goals (SDGs) represents a common framework of international cooperation to promote sustainable development. Nutrition is key point SDG 2 ‘End hunger, achieve food security and improved nutrition agriculture’ an essential component achieving many other targets: overall, nutritional aspects SDGs aim healthy diets ensure globally. While undernutrition minimal concern in European Union Member States, trends childhood obesity are still...
SUMMARY Background In February 2020, a locally-acquired COVID-19 case was detected in Lombardia, Italy. This the first signal of ongoing transmission SARS-CoV-2 country. The outbreak rapidly escalated to national level epidemic, amid WHO declaration pandemic. Methods We analysed data from case-based integrated surveillance system all RT-PCR confirmed infections as March 24 th collected Italian regions and autonomous provinces. Here we provide descriptive epidemiological summary on 62,843...
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown post-lockdown periods using a retrospective cohort study with 38,534,169 citizens 222,875 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density region of residence were conducted evaluate area-level incidence, case-hospitalisation rate case-fatality. During post-lockdown, but not higher incidence cases observed most...
On March 11, 2020, Italy imposed a national lockdown to curtail the spread of severe acute respiratory syndrome coronavirus 2. We estimate that, 14 days after lockdown, net reproduction number had dropped below 1 and remained stable at »0.76 (95% CI 0.67-0.85) in all regions for >3 following weeks.
Data on effectiveness of the BioNTech/Pfizer COVID-19 vaccine in real-world settings are limited. In a study 6,423 healthcare workers Treviso Province, Italy, we estimated that, within time intervals 14–21 days from first and at least 7 second dose, preventing SARS-CoV-2 infection was 84% (95% confidence interval (CI): 40–96) 95% CI: 62–99), respectively. These results could support ongoing vaccination campaigns by providing evidence for targeted communication.
COVID-19 dramatically influenced mortality worldwide, in Italy as well, the first European country to experience Sars-Cov2 epidemic. Many countries reported a two-wave pattern of deaths; however, studies comparing two waves are limited. The objective study was compare all-cause excess between that occurred during year 2020 using nationwide data. All-cause mortalities were estimated negative binomial models with time modeled by quadratic splines. also applied estimate deaths “not directly...
Abstract To counter the second COVID-19 wave in autumn 2020, Italian government introduced a system of physical distancing measures organized progressively restrictive tiers (coded as yellow, orange, and red) imposed on regional basis according to real-time epidemiological risk assessments. We leverage data from integrated surveillance publicly available mobility evaluate impact three-tiered restriction human activities, SARS-CoV-2 transmissibility hospitalization burden Italy. The...
During 2022, Omicron became the dominant SARS-CoV-2 variant in Europe. This study aims to assess impact of such on severe disease from compared with Delta Italy.Using surveillance data, we assessed risk developing COVID-19 infection individuals aged ≥12 years using a multilevel negative binomial model adjusting for sex, age, vaccination status, occupation, previous infection, weekly incidence, and geographical area. We also analyzed interaction between sequenced variant, status.We included...
Effectiveness against severe COVID-19 of a second booster dose the bivalent (original/BA.4-5) mRNA vaccine 7-90 days post-administration, relative to first an received ≥ 120 earlier, was ca 60% both in persons 60 years never infected and those > 6 months before. Relative effectiveness 4-6 earlier indicated no significant additional protection (10%; 95% CI: -44 44). A vaccination after latest infection may be warranted.
ABSTRACT Using a common protocol across seven countries in the European Union/European Economic Area, we estimated XBB.1.5 monovalent vaccine effectiveness (VE) against COVID‐19 hospitalisation and death booster‐eligible ≥ 65‐year‐olds, during October–November 2023. We linked electronic records to construct retrospective cohorts used Cox models estimate adjusted hazard ratios derive VE. VE for was, respectively, 67% (95%CI: 58–74) 42–81) 65‐ 79‐year‐olds 66% 57–73) 72% 51–85) 80‐year‐olds....
International literature suggests that disadvantaged groups are at higher risk of morbidity and mortality from SARS-CoV-2 infection due to poorer living/working conditions barriers healthcare access. Yet, date, there is no evidence this disproportionate impact on non-national individuals, including economic migrants, short-term travellers refugees.We analyzed data the Italian surveillance system all COVID-19 laboratory-confirmed cases tested positive beginning outbreak (20th February) 19th...
During predominant circulation of SARS-CoV-2 Omicron XBB.1.5 and other XBB sublineages (April-June 2023), we found that a second or third booster Comirnaty bivalent Original/Omicron BA.4-5 mRNA vaccine, versus first received at least 120 days earlier, was effective in preventing severe COVID-19 for more than 6 months post-administration persons 60 years above. In view autumn 2023 vaccination campaigns, use vaccines might be warranted until monovalent targeting XBB.1 become available.
As in 2018, when a large West Nile virus (WNV) epidemic occurred, the 2022 vector season Italy was marked by an early onset of WNV circulation mosquitoes and birds. Human infections were limited until July, we observed rapid increase number cases. We describe epidemiology human animal surveillance for compare more consolidated data June July with same period 2018.
We explored the risk factors associated with SARS-CoV-2 reinfections in Italy between August 2021 and March 2022. Regardless of prevalent virus variant, being unvaccinated was most relevant factor for reinfection. The reinfection increased almost 18-fold following emergence Omicron variant compared Delta. A severe first infection age over 60 years were significant
Abstract Background The difficulty in identifying SARS‐CoV‐2 infections has not only been the major obstacle to control COVID‐19 pandemic but also quantify changes proportion of resulting hospitalization, intensive care unit (ICU) admission, or death. Methods We developed a model transmission and vaccination informed by official estimates time‐varying reproduction number estimate that occurred Italy between February 2020 2022. Model outcomes were compared with Italian National surveillance...
Background Toscana virus (TOSV) is transmitted to humans through bites of infected sand flies. Neuroinvasive TOSV infections are leading causes meningitis/encephalitis in southern Europe and notifiable Italy since 2016. In 2022–23, experienced extreme climate anomalies a concomitant increase mosquito tick-borne disease transmission. Aim To identify the spatiotemporal distribution risk groups neuroinvasive 2022–23 vs 2016–21. Methods We retrospectively described all autochthonous,...
Collaborative hubs that integrate multiple teams to generate ensemble projections and forecasts for shared targets are now regarded as state-of-the-art in epidemic predictive modeling. In this paper, we introduce Influcast, Italy's first forecasting hub influenza-like illness. During the 2023/2024 winter season, Influcast provided 20 rounds of forecasts, involving five eight models predict illness incidence up four weeks advance at national regional administrative level. The individual were...
Background During the first year of COVID-19 pandemic, vaccination programmes targeted children and adolescents to prevent severe outcomes SARS-CoV-2 infection. Aim To estimate vaccine effectiveness (VE) against hospitalisation due in paediatric population, among those with without previously documented Methods We established a fixed cohort followed for 12 months Denmark, Norway, Italy, Luxembourg, Navarre (Spain) Portugal using routine electronic health registries. The study commenced...