A5075152204- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- Genetic and phenotypic traits in livestock
- Virology and Viral Diseases
- Hepatitis Viruses Studies and Epidemiology
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Syphilis Diagnosis and Treatment
- Meat and Animal Product Quality
- Reproductive tract infections research
- Hepatitis C virus research
- Viral Infections and Vectors
- HIV/AIDS Impact and Responses
- COVID-19 Impact on Reproduction
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Herpesvirus Infections and Treatments
- Viral Infections and Immunology Research
- COVID-19 diagnosis using AI
- Viral Infections and Outbreaks Research
- Veterinary medicine and infectious diseases
World Health Organization
2021-2023
University of Calgary
2021
Public Health England
2014-2018
Mortimer Market Centre
2010
University College London
2010
Institut de Veille Sanitaire
2003-2009
European Monitoring Centre for Drugs and Drug Addiction
2009
Health Protection Agency
2008
Institut Pasteur
2004
Università degli Studi della Tuscia
1989
Background The declaration of Coronavirus disease 2019 (COVID‐19) as a Public Health Emergency International Concern (PHEIC) on 30 January 2020 required rapid implementation early investigations to inform appropriate national and global public health actions. Methods suite existing pandemic preparedness generic epidemiological investigation protocols was rapidly adapted for COVID‐19, branded the ‘UNITY studies’ promoted globally standardized quality studies. Ten were developed investigating...
ABSTRACT Using a common protocol across seven countries in the European Union/European Economic Area, we estimated XBB.1.5 monovalent vaccine effectiveness (VE) against COVID‐19 hospitalisation and death booster‐eligible ≥ 65‐year‐olds, during October–November 2023. We linked electronic records to construct retrospective cohorts used Cox models estimate adjusted hazard ratios derive VE. VE for was, respectively, 67% (95%CI: 58–74) 42–81) 65‐ 79‐year‐olds 66% 57–73) 72% 51–85) 80‐year‐olds....
To standardize serological surveillance to compare rubella susceptibility in Australia and 16 European countries, measure progress towards international disease-control targets.Between 1996 2004, representative serum banks were established 17 countries by collecting residual sera or community sampling. Serum tested each country assay results standardized. With a questionnaire, we collected information on current past vaccination programmes country. The percentage of seronegative (< 4 IU/ml)...
SUMMARY Mumps outbreaks have recently been recorded in a number of highly vaccinated populations. We related seroprevalence, epidemiological and vaccination data from 18 European countries participating The Sero-Epidemiology Network (ESEN) to their risk mumps order inform strategies. Samples national population serum banks were collected, tested for IgG antibodies standardized international comparisons. A comparative analysis between was undertaken using age-specific seroprevalence...
Risk factors for leptospirosis in France were investigated to improve the vaccination program this disease. Data from 90 hospitalized case patients and 169 matched control subjects analyzed a case-control study. Skin lesions, canoeing, contact with wild rodents, country residence independently associated leptospirosis, emphasizing that leisure activity is risk factor illness.
HIV-prevention measures specific to injection drug users (IDUs), such as opioid substitution treatment and needle-and-syringe programs, are not provided in many countries where use is endemic. We describe the incidence of diagnosed HIV infection IDUs availability coverage programs European Union 5 middle- high-income countries. Countries with greater provision both prevention 2000 2004 had lower 2005 2006.
SUMMARY To inform current and future vaccination strategies, we describe the seroepidemiology of hepatitis B virus (HBV) infection in ten representative European countries using standardized serology that allowed international comparisons. Between 1996 2003, national serum banks were compiled by collecting residual sera or community sampling; then tested each country its preferred enzyme immunoassays testing algorithm, assay results standardized. Information on past HBV programmes was also...
SUMMARY The aim of the European Sero-Epidemiology Network is to establish comparability serological surveillance vaccine-preventable diseases in Europe. designated reference laboratory (RL) for measles, mumps, rubella (MMR) prepared and tested a panel 151 sera by enzyme immunoassay (rEIA). Laboratories 21 countries antibodies against MMR using their usual assay (a total 16 different EIAs) results were plotted order obtain equations standardization national serum surveys. RL also plaque...
Evidence for relationships between alcohol misuse, sexual risk behaviour and adverse health outcomes exists from both population-level data studies undertaken in specific groups. We examine changes these associations using representative two consecutive surveys. Probability surveys conducted 1990/91 again 2000/01 involving interviews with British residents aged 16–44. The proportion reporting being drunk as their main reason first heterosexual intercourse increased 2.5% among those born...
ABSTRACT Introduction The aim of the study was to assess seroprevalence SARS‐CoV‐2 in Republika Srpska, Bosnia and Herzegovina, after five waves COVID‐19 1 year introduction vaccination better understand true extent pandemic population Srpska role achieving herd immunity. Methods population‐based conducted from December 2021 February 2022 a group 4463 individuals Srpska. Total anti–SARS‐CoV‐2 antibodies were determined serum specimens using Wantai total antibody ELISA assay. Quantitative...
Background During the first year of COVID-19 pandemic, vaccination programmes targeted children and adolescents to prevent severe outcomes SARS-CoV-2 infection. Aim To estimate vaccine effectiveness (VE) against hospitalisation due in paediatric population, among those with without previously documented Methods We established a fixed cohort followed for 12 months Denmark, Norway, Italy, Luxembourg, Navarre (Spain) Portugal using routine electronic health registries. The study commenced...
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In Brief Background: Most studies of human papillomavirus (HPV) epidemiology have employed DNA testing, which measures current infections. Serum antibodies offer a longer-term marker infection in individuals who seroconvert and can therefore provide additional information about the exposure populations to HPV. Methods: Sera from population-based sample males females aged 10 49 years, England, were tested for type-specific HPV using multiplexed competitive Luminex assay previously defined...
BackgroundIntegrase inhibitor (INSTI) with boosted darunavir (DRV/r), a regimen high-resistance barrier, avoiding NRTI toxicities, might be switching option in children living HIV (CLWHIV).MethodsSMILE is randomised non-inferiority trial evaluating safety and antiviral efficacy of once-daily INSTI + DRV/r vs. continuing on current standard-of-care (SOC) triple ART (2NRTI PI/NNRTI) virologically-suppressed CLWHIV aged 6–18 years. The primary outcome the proportion confirmed HIV-RNA ≥50...
In recent years there has been interest in websites as a means of increasing access to free chlamydia tests through the National Chlamydia Screening Programme (NCSP) England. We aimed describe and evaluate online testing within NCSP. analysed NCSP data (2006–2010) for 15–24 year olds from 71/95 programme areas England where site codes were available identify ordered internet. The characteristics people using services 2010 compared with those general practice (GP) or community sexual...
SUMMARY Serological surveys for diphtheria were conducted in six European countries including Czech Republic, Hungary, Ireland, Latvia, Luxembourg, Slovakia and one country outside Europe, Israel. For each country, a nationally representative population sample was collected across the entire age range tested antibodies to toxin. Although national laboratory used its preferred assay, results all standardized those of vitro neutralization test expressed international units (IU) which allowed...
For the last 10 years there has been an epidemic of hepatitis C virus (HCV) infection in men who have sex with (MSM) Europe, North America and Australia. The majority those infected are also HIV-positive it is unclear to what extent HIV-negative MSM at increased risk HCV. This study provides first examination association between HIV serostatus a sample recruited community settings.A total 1121 participants completed short questionnaire 2008/2009 giving demographic behavioural data, donated...
Hepatitis C (HCV) diagnosis and care is a major challenge for people who use illicit drugs, characterised by low rates of testing treatment engagement globally. New approaches to fostering are needed. We explored the acceptability remote forms HCV including self-testing self-sampling among drugs in London, UK.A qualitative rapid assessment was undertaken with stakeholders UK. Focus groups were held men have sex engaged drug use, currently inject formerly injected (22 participants across 3...
There are an estimated 740 000 people living with HIV or AIDS in western and central Europe today, 1.7 million the neighbouring countries of eastern Central Asia