A5022907062- Viral gastroenteritis research and epidemiology
- HIV, Drug Use, Sexual Risk
- Viral Infections and Immunology Research
- HIV/AIDS Research and Interventions
- Hepatitis Viruses Studies and Epidemiology
- Influenza Virus Research Studies
- Respiratory viral infections research
- Animal Virus Infections Studies
- Escherichia coli research studies
- COVID-19 epidemiological studies
- Congenital Anomalies and Fetal Surgery
- Sex work and related issues
- Clostridium difficile and Clostridium perfringens research
- Viral Infections and Outbreaks Research
- Vaccine Coverage and Hesitancy
- Virus-based gene therapy research
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- Hepatitis B Virus Studies
- Child Nutrition and Water Access
- Viral-associated cancers and disorders
- HIV Research and Treatment
- HIV/AIDS Impact and Responses
- Pneumonia and Respiratory Infections
World Health Organization Regional Office for South-East Asia
2020-2022
International Centre for Diarrhoeal Disease Research
2009-2020
BRAC University
2019
Independent University
2017
Creative Commons
2016
Save the Children
2016
Rega Institute for Medical Research
2010
Nagasaki University
2010
Osaka University
2010
National Institute of Cancer Research and Hospital
2006
G12 rotaviruses were first detected in diarrheic children the Philippines 1987, but no further cases reported until 1998. However, have been all over world recent years. Here, we report worldwide variations of to investigate evolutionary mechanisms by which they managed spread globally a short period time. We sequenced complete genomes (11 segments) nine isolated Bangladesh, Belgium, Thailand, and compared them with other rotavirus strains. Our genetic analyses revealed that after...
Abstract Approximately 20,000 stool specimens from patients with diarrhea visiting an urban and a rural hospital in Bangladesh during January 2001–May 2006 were tested for group A rotavirus antigen, 4,712 (24.0%) positive. G P genotyping was performed on subset of 10% the positive samples (n = 471). During 2001–2005 seasons, G1P[8] (36.4%) G9P[8] (27.7%) dominant strains, but G2[4] G12P[6] present 15.4% 3.1% rotavirus-positive patients, respectively. 2005–06 season, G2P[4] (43.2%) appeared...
Pneumonia is the leading cause of child mortality worldwide. The role influenza in childhood pneumonia tropical developing countries poorly understood. We undertook population-based surveillance among low-income urban preschool children to determine its pneumonia.Longitudinal prospective active was conducted randomly selected households a poor area Dhaka. Nasopharyngeal washes were collected from 1 5 for culture isolation. Clinical data at clinical presentation and through illness...
Background The declaration of Coronavirus disease 2019 (COVID‐19) as a Public Health Emergency International Concern (PHEIC) on 30 January 2020 required rapid implementation early investigations to inform appropriate national and global public health actions. Methods suite existing pandemic preparedness generic epidemiological investigation protocols was rapidly adapted for COVID‐19, branded the ‘UNITY studies’ promoted globally standardized quality studies. Ten were developed investigating...
Previous studies have shown that selected strains of lactobacilli are administered orally result in a modest reduction diarrhea duration. However, duration alone is not considered optimal for therapeutic evaluation any agent diarrhea.To examine the effect new probiotic, Lactobacillus paracasei strain ST11 (ST11), acute childhood by using criteria recommended World Health Organization.In randomized, double-blind, placebo-controlled clinical trial, 230 male infants and young children, 4 to 24...
ABSTRACT A novel rotavirus strain (Dhaka6) isolated from a 21-year-old Bangladeshi male patient was characterized by sequence analysis of its VP7 and VP4 gene segments. Phylogenetic the Dhaka6 revealed common evolutionary lineage with porcine G11 strains. This isolate is first reported infecting human host. Comparison sequences all currently recognized 24 different P genotypes only low nucleotide (54 to 71%) amino acid (52 76%) identities. lack high similarity in indicates that represents...
Background Recent population-based estimates in a Dhaka low-income community suggest that influenza was prevalent among children. To explore the epidemiology and seasonality of throughout country all age groups, we established nationally representative hospital-based surveillance necessary to guide prevention control efforts. Methodolgy/Principal Findings We conducted influenza-like illness severe acute respiratory sentinel 12 hospitals across Bangladesh during May 2007–December 2008....
G11 rotaviruses are believed to be of porcine origin. However, a limited number have been recently isolated from humans in combination with P[25], P[8], P[6], and P[4]. To investigate the evolutionary relationships these strains, we analyzed complete genomes 2 human G11P[25] G11P[8] 3 reference strains. Most 11 gene segments 7 strains belonged genotype 1 (Wa-like). phylogenetic clustering patterns suggested that an unknown strain new I12 VP6 was transmitted population, which it acquired...
To determine how much influenza contributes to severe acute respiratory illness (SARI), a leading cause of death in children, among people all ages Bangladesh.Physicians obtained nasal and throat swabs test for virus from patients who were hospitalized within 7 days the onset infection (SARI) or consulted as outpatients influenza-like (ILI). A community health care utilization survey was conducted proportion hospital catchment area residents sought at study hospitals calculate incidence...
Background Pneumonia is the leading cause of childhood death in Bangladesh. We conducted a longitudinal study to estimate incidence virus-associated pneumonia children aged <2 years low-income urban community Dhaka, Methods followed cohort for two years. collected nasal washes when presented with respiratory symptoms. Study physicians diagnosed cough and age-specific tachypnea positive lung findings as case-patients. tested samples syncytial virus (RSV), rhinoviruses, human metapneumovirus...
To determine relapse rates and associated factors among people who use drugs (PWUDs) attending abstinence-oriented drug treatment clinics in Dhaka, Bangladesh. A cohort of male female PWUDs admitted to the 3-month detoxification-rehabilitation programmes three non-governmental organisation-run Bangladesh were interviewed on admission over following 5 months, which included first 2 months after discharge. The study subjects comprised 150 110 had been taking opiates/opioids, cannabis or other...
The rates of influenza illness and associated complications are high among children in Bangladesh. We assessed the clinical efficacy safety a Russian-backbone live attenuated vaccine (LAIV) at two field sites Bangladesh.Between Feb 27 April 9, 2013, aged 2-4 years urban Kamalapur rural Matlab, Bangladesh, were randomly assigned 2:1 ratio, according to computer-generated schedule, receive one intranasal dose LAIV or placebo. After vaccination, we monitored weekly home visits until Dec 31,...
Background Rotavirus vaccines are now globally recommended by the World Health Organization (WHO), but in early 2009 WHO’s Strategic Advisory Group of Experts on Immunization reviewed available data and concluded that there was no evidence for efficacy or effectiveness a two-dose schedule human rotavirus vaccine (HRV; Rotarix) given at 6 10 wk age. Additionally, programmatic vaccination, including possible indirect effects, has not been assessed low-resource populations Asia. Methods...
Vibrio cholerae serogroup O139, now considered to be the second organism capable of causing epidemic severe dehydrating cholera, contains a capsular polysaccharide which makes it difficult for used in conventional vibriocidal antibody assay optimized V. O1. After modification procedure, involved use specific bacterial strains, lower inoculum, and increased amounts complement, responses O139 were measured acute- convalescent-phase sera from 33 O139-infected 18 O1-infected patients single...
Background. Diarrhea is an important public health concern in developing countries such as Bangladesh. children that persists for 14 days or more occurs 7% of patients Bangladesh and frequently results death. Astrovirus has been demonstrated a cause acute nosocomial diarrhea can be excreted prolonged periods, yet its importance among country like not investigated. Methods. We tested 629 stool specimens from with diarrhea, 153 persistent 175 76 hospitalized who were sampled repeatedly to...
ABSTRACT Group C rotaviruses were detected by reverse transcription-PCR in 14 (2.3%) of 611 group A rotavirus-negative stool specimens from the patients admitted to International Centre for Diarrhoeal Disease Research, Bangladesh hospital, Dhaka, Bangladesh, during July December 2003. The low rate detection suggested that infection with was an uncommon cause hospitalization due gastroenteritis. In addition, coinfections pathogenic enteric bacteria frequently observed rotavirus-infected...
ABSTRACT Bacillary dysentery caused by Shigella species is a public health problem in developing countries including Bangladesh. Although, shigellae-contaminated food and drinks are often the source of epidemic's spread, possible presence pathogen transmission it through environmental waters have not been adequately examined. We analyzed surface collected Dhaka, Bangladesh, for shigellae combination PCR assays followed concentration culturing PCR-positive samples. Analysis 128 water samples...