A5072876782- Transition Metal Oxide Nanomaterials
- Hepatitis Viruses Studies and Epidemiology
- ZnO doping and properties
- Gas Sensing Nanomaterials and Sensors
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Copper-based nanomaterials and applications
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Viral gastroenteritis research and epidemiology
- Semiconductor materials and devices
- Copper Interconnects and Reliability
- Liver Disease Diagnosis and Treatment
- Bacteriophages and microbial interactions
- Theoretical and Computational Physics
- Surface and Thin Film Phenomena
- nanoparticles nucleation surface interactions
- Viral Infections and Immunology Research
- Electrochemical Analysis and Applications
- Analytical Chemistry and Sensors
- Advanced Chemical Sensor Technologies
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoporous metals and alloys
- Molecular Junctions and Nanostructures
- Semiconductor materials and interfaces
Public Health Agency of Sweden
2015-2022
Uppsala University
1999-2011
Max Planck Institute for Molecular Genetics
2011
Stockholm University
2002-2005
Texas A&M University
2005
Gdańsk University of Technology
2004
Electrical transport and optical properties were investigated in porous thin films consisting of ${\mathrm{In}}_{2}{\mathrm{O}}_{3}:\mathrm{Sn}$ (indium tin oxide, ITO) nanoparticles with an initial crystallite size $\ensuremath{\sim}16 \mathrm{nm}$ a narrow distribution. Temperature dependent resistivity was measured the $77<t<300\mathrm{K}$ temperature interval for samples annealed at $573<~{t}_{\mathrm{A}}<~1073\mathrm{K}$ range. Samples...
Between 1 June 2016 and 31 May 2017, 17 European Union (EU) Economic Area countries reported 4,096 cases associated with a multi-country hepatitis A (HA) outbreak. Molecular analysis identified three co-circulating virus (HAV) strains of genotype IA: VRD_521_2016, V16–25801 RIVM-HAV16–090. We categorised as confirmed, probable or possible, according to the EU outbreak case definitions. Confirmed were infected one strains. investigated characteristics strain-specific risk factors for...
In May 2013, Italy declared a national outbreak of hepatitis A, which also affected several foreign tourists who had recently visited the country. Molecular investigations identified some cases as infected with an identical strain A virus subgenotype IA. After additional European Union/European Economic Area (EU/EEA) countries reported locally acquired and travel-related associated same outbreak, international investigation team was convened, case definition issued harmonisation...
With the rapid development of ribosome field in recent years a quick, simple and high-throughput method for purification bacterial is demand. We have designed new strain Escherichia coli (JE28) by an in-frame fusion nucleotide sequence encoding hexa-histidine affinity tag at 3′-end single copy rplL gene (encoding ribosomal protein L12) chromosomal site wild-type MG1655. As result, JE28 produces homogeneous population ribosomes (His) 6 -tagged C-termini all four L12 proteins. Furthermore, we...
Epidemiological data are crucial to monitoring progress towards the 2030 Hepatitis C Virus (HCV) elimination targets. Our aim was estimate prevalence of chronic HCV infection (cHCV) in European Union (EU)/European Economic Area (EEA) countries 2019. Multi-parameter evidence synthesis (MPES) used produce national estimates cHCV defined as: π = πrecρrec + πexρex πnonρnon; πrec, πex, and πnon represent among recent people who inject drugs (PWID), ex-PWID, non-PWID, respectively, while ρrec,...
Regulation of RNA polymerase during initiation, elongation, and termination transcription is mediated in part by interactions with intrinsic regulatory signals encoded the DNA that contact enzyme. These include contacts to an 8–9-bp RNA:DNA hybrid within active-site cleft enzyme, melted nontemplate strand vicinity hybrid, exiting upstream ∼20 bp duplex downstream active site. Based on characterization amino acid substitution (G1161R) a deletion (Δ1149–1190) jaw domain bacterial largest...
The ribosomal stalk in bacteria is composed of four or six copies L12 proteins arranged dimers that bind to the adjacent sites on protein L10, spanning 10 amino acids each from L10 C-terminus. To study why multiple are required ribosome, we created a chromosomally engineered Escherichia coli strain, JE105, which peripheral dimer binding site was deleted. Thus JE105 harbors ribosomes with only single dimer. Compared MG1655, parental strain two dimers, showed significant growth defect...
Between June-September 2018, 20 hepatitis A cases were notified in six counties Sweden. Combined epidemiological and microbiological investigations identified imported frozen strawberries produced Poland as the source of outbreak. Sequence analysis confirmed outbreak strain IB with 100 % identity respective batch was withdrawn. Sharing sequence information internationally led to identification 14 additional Austria, linked from same producer.
Porous tungsten oxide nanoparticle films were prepared by reactive gas evaporation. The structure was studied x-ray diffraction and scanning electron microscopy, the oxygen nonstoichiometry inferred photoelectron spectroscopy, elastic recoil detection analysis, neutron scattering. Specifically, consisted of WO3−x with 0.25&lt;x&lt;0.4. optical electrical data consistent formation small polarons having a radius 5–6Å. infrared data, used to extract information on phonon energies,...
Effective medium theory was used to model optical properties in the 0.3 – 30 μm wavelength range for films comprised of nanoparticles a transparent conducting oxide that are connected percolating network characterized by filling factor f. The is based on charge carrier density ne and resistivity ρ particles, it enables analyses these microscopic parameters upon posttreatment film. interpret data spin coated layers consisting indium tin (i.e., In2O3:Sn) with f close percolation limit. It...
From January to June 2018, two ongoing hepatitis A outbreaks affected travellers returning from Morocco and cases in Europe without travel history, resulting 163 patients eight European countries. Most interviewed travel-related were unaware of the risk Morocco. Molecular analysis revealed distinct virus (HAV) strains (subgenotype IA DK2018_231; subgenotype IB V18–16428). Vaccination recommendations should be emphasised increase awareness among non-immune HAV-endemic
Conduction noise measurements were carried out in the 0.3–45 Hz frequency range on Au films covered by a thin layer of tungsten trioxide (WO3) nanoparticles. Exposing to alcohol vapor resulted gradually increased intensity which went through maximum after an exposure time order 15 min. The could increase several orders magnitude above initial level. Longer times made decrease and approach its original value. This effect was not observed absence WO3 phenomenon is discussed terms new 'invasion...
Nanocrystalline gold films were made by advanced gas deposition. The mean crystallite diameter lay between ∼10 and ∼80 nm depending on substrate temperature during deposition annealing post-treatment, as found x-ray diffractometry transmission electron microscopy. Temperature dependent resistivity ρ was measured in the 4&lt;T&lt;300 K range. log versus T relationship displayed a discontinuity at Tcr lying 10 7.2 size. This can be understood result of being dominated scattering...
Introduction Sequence-based typing of hepatitis A virus (HAV) is important for outbreak detection, investigation and surveillance. In 2013, sequencing was central to resolving a large European Union (EU)-wide related frozen berries. However, as the sequenced HAV genome regions were only partly comparable between countries, results not always conclusive. Aim The objective gather information on surveillance in EU/European Economic Area (EEA) countries find ways harmonise their procedures,...
It has previously been shown that resistance fluctuations in resistive sensors provide enhanced sensitivity and selectivity for gas detection. We report measurements analysis of non-Gaussian components nanoparticle Pd z ( WO 3 ) 1- film sensors, with being 0.01 or 0.12, different ambients. These can be characterized by higher-order spectra. Contour plots are given bispectra, integrated bispectra trispectra. The phase the spectra is analyzed as well.
Advanced gas deposition was used to produce nanocrystalline gold films under conditions giving four different rates. Grain growth and structural modification of the grain boundaries were probed during annealing by use in situ electrical transport measurements. Time dependent resistivity data fitted a relaxation model whose activation energy went up upon increased isothermal temperature. The boundary transmission coefficient for samples scaled, certain limit, with rate; this is believed be...
BackgroundSwedish hepatitis A surveillance includes sequence-based typing, but its contribution to outbreak detection in relation epidemiological investigations has not been fully evaluated.AimTo evaluate the role of typing and describe epidemiology Sweden improve surveillance.MethodsWe retrospectively investigated virus sequences 447 cases notified 2009-18. We performed a phylogenetic analysis evolutionary distances identify with similar (≥ 459/460 identical nt VP1/P2A junction). Unique...
To monitor Sweden's progress towards the WHO goal of eliminating viral hepatitis, we estimated prevalence, notification rate, and liver-related morbidity mortality for diagnosed hepatitis B virus (HBV) C (HCV) infections in 2015 2018.We identified cases within National System Notifiable Diseases obtained data on treatment whether case was deceased or not. We calculated rates per 100,000, proportion newly with liver disease at time diagnosis, all who died from disease. Poisson 95% confidence...
Hepatitis B virus (HBV) infection remains a global health threat. The World Health Organization (WHO) established goal to eliminate HBV as public threat by 2030, and defined targets for key interventions achieve that goal. We evaluated burden relevant national recommendations progress towards WHO in circumpolar countries. Viral hepatitis experts of countries were surveyed regarding their country's HBV, achievement authority prevention control. Eight nine responded. All continue see new...