A5041095371- Influenza Virus Research Studies
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Pneumonia and Respiratory Infections
- Animal Disease Management and Epidemiology
- Viral Infections and Outbreaks Research
- Hepatitis B Virus Studies
- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Bartonella species infections research
- Diabetes and associated disorders
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- COVID-19 Clinical Research Studies
- HIV-related health complications and treatments
- Hepatitis Viruses Studies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Child and Adolescent Health
- Nosocomial Infections in ICU
- Immunodeficiency and Autoimmune Disorders
Carol Davila University of Medicine and Pharmacy
2016-2025
National Institute of Research and Development for Biological Sciences
2016-2025
Institutul Clinic Fundeni
2025
Innovative Medicines Initiative
2021
Weatherford College
2021
Avila University
2019
Institutul Cantacuzino
2009-2018
Clinical Emergency Hospital Bucharest
2016
Ministerul Sanatatii
1999-2006
Results from a European multicentre case-control study reported by Marta Valenciano and colleagues suggest good protection the pandemic monovalent H1N1 vaccine against pH1N1 no effect of 2009–2010 seasonal influenza on H1N1.
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Since the 2008/9 influenza season, I-MOVE multicentre case–control study measures vaccine effectiveness (VE) against medically-attended influenza-like-illness (ILI) laboratory confirmed as influenza. In 2011/12, European studies reported a decline in VE A(H3N2) within season. Using combined data from 2010/11 to 2014/15 we studied effects of time since vaccination on type/subtype-specific VE. We modelled by using restricted cubic spline, controlling for potential confounders (age, sex, onset,...
In the third season of I-MOVE (Influenza Monitoring Vaccine Effectiveness in Europe), we undertook a multicentre case-control study based on sentinel practitioner surveillance networks eight European Union (EU) member states to estimate 2010/11 influenza vaccine effectiveness (VE) against medically-attended influenza-like illness (ILI) laboratory-confirmed as influenza.Using systematic sampling, practitioners swabbed ILI/ARI patients within seven days symptom onset. We compared...
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Within I-MOVE (European programme to monitor seasonal and pandemic influenza vaccine effectiveness (IVE)) five countries conducted IVE pilot case-control studies in 2008-9. One hundred sixty sentinel general practitioners (GP) swabbed all elderly consulting for influenza-like illness (ILI). Influenza confirmed cases were compared negative controls. We a pooled analysis obtain summary the age group of >or=65 years. measured each study assessed heterogeneity between qualitatively using I2...
In the first five I-MOVE (Influenza Monitoring Vaccine Effectiveness in Europe) influenza seasons vaccine effectiveness (VE) results were relatively homogenous among participating study sites. 2013-2014, we undertook a multicentre case-control based on sentinel practitioner surveillance networks six European Union (EU) countries to measure 2013-2014 VE against medically-attended influenza-like illness (ILI) laboratory-confirmed as influenza. Influenza A(H3N2) and A(H1N1)pdm09 viruses...
Abstract Background Since 2011, the Global Influenza Hospital Surveillance Network (GIHSN) has used active surveillance to prospectively collect epidemiological and virological data on patients hospitalized with influenza virus infection. Here, we describe strain circulation in GIHSN participant countries during 2017–2018 season examine factors associated complicated hospitalization among admitted laboratory-confirmed illness. Methods The study enrolled who were a hospital previous 48 h...
Recording real-time data of vaccinations performed, vaccine stocks, and adverse events following immunization is a particularly useful activity in the effective development any vaccination campaign or program, guiding decisions public health authorities. The aim this paper to present benefits National Electronic Registry Vaccinations providing information for optimization healthcare policies, specifically related COVID-19 vaccination.We performed descriptive study using available reports...
Our study describes the frequency and severity of COVID-19 in HCWs estimates dynamic risk COVID-19-related events. We actively surveyed all from a tertiary infectious disease hospital 26 February 2020 to 31 May 2023. Of 1220 HCWs, 62.9% (767) had at least one episode. The under 29 years (
Botulism is a priority disease worldwide because it has very severe course of evolution that can lead to death. This paper aims describe the main epidemiological characteristics botulism cases confirmed in Romania over 14 years (2007–2020). We performed retrospective study using publicly available national surveillance data and reported National Institute Public Health. A total 325 foodborne were Romania, with no infant or wound botulism. Most (125, 38.5%) among young adults (25–44 old),...
Aim Romania is currently facing a prolonged measles outbreak. The aim of the study was to analyse circulating human virus (HMV) strains by combining whole genome sequencing (WGS) with phylogenetic analysis, focus on haemagglutinin gene. Methods We conducted an observational in first five months 2024, which 168 patients diagnosed were randomly included. have evaluated clinical and epidemiological differences between children adults. Screening for samples be sequenced performed commercial kit...
Abstract Background Despite the availability of efficient and safe vaccines, measles remains a significant public health threat worldwide. In Romania, there has been resurgence since March 2023, leading up to an outbreak in early December, with many cases reported including among adult population. Consequently, this study aims present epidemiological, clinical, laboratory data adolescents adults hospitalized for measles.Table 1.Patient demographics, paraclinical complications...
We conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination underlying conditions was collected. Using logistic regression, we measured IVE adjusted for potential...
Background Results of previous influenza vaccination effects on current season vaccine effectiveness (VE) are inconsistent. Objectives To explore VE among population targeted for vaccination. Methods We used 2011/2012 to 2016/2017 I‐MOVE primary care multicentre test‐negative data. For each season, we compared adjusted (aVE) between individuals vaccinated and unvaccinated in season. Using both seasons as a reference, then aVE seasons, only, only. included 941, 2645 959 influenza‐like illness...
Two main mechanisms contribute to the continuous evolution of influenza viruses: accumulation mutations in hemagglutinin and neuraminidase genes (antigenic drift) genetic re-assortments shift). Epidemiological surveillance is important identifying new variants viruses with potentially increased pathogenicity transmissibility. In order characterize 2019/20 epidemic Romania, 1042 respiratory samples were collected from consecutive patients hospitalized acute infections National Institute for...
The COVID-19 pandemic continues to be a major public health problem in most countries of the world, especially developing with an underfunded healthcare system. We aim present comparative profile epidemiological characteristics Romania and neighboring countries, which have similar onset socio-cultural pattern. A descriptive study was performed using data collected from various official websites regarding demography, morbidity, mortality, vaccination, testing capacity. included were Romania,...
Abstract Influenza viruses are responsible for a high number of infections and hospitalizations every year. In this study, we aimed to identify clinical host-specific factors that influence the duration hospitalization progression acute respiratory failure (ARF) in influenza. We performed an analysis data from prospective active influenza surveillance study was conducted over five seasons (2018/19 2022/23). A total 1402 patients with were included analysis, majority which (64.5%) children...
In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% CI: 2 43) among 65-79-year-olds and 13% -15 30) those ≥ 80 years. As the component has not changed for 2017/18, physicians public health experts should be aware that could low where viruses predominate.
Infections in severe burns and their etiology are will remain a big concern for the medical field. The multi-drug resistant strains of bacteria challenge today's medicine. aim our study was to identify etiological spectrum bacterial infections burn patients Romania patterns. We performed prospective that included 202 adult admitted intensive care unit (ICU) Clinical Emergency Hospital Plastic, Reconstructive Surgery Burns, Bucharest, (CEHPRSB), from 1 October 2018 April 2022, period which...
In Europe, annual influenza vaccination is recommended to elderly. From 2011 2014 and in 2015-16, we conducted a multicentre test negative case control study hospitals of 11 European countries measure vaccine effectiveness (IVE) against laboratory confirmed hospitalised among people aged ≥65years. We pooled four seasons data IVE by past exposures vaccination. swabbed patients admitted for clinical conditions related with onset severe acute respiratory infection ≤7days before admission. Cases...
The Omicron variant of SARS-CoV-2 has caused a large number cases and hospitalizations in the pediatric population. Infants due to their age are susceptible viral infections that may have worse prognosis. Therefore, aim current study been characterize clinical features outcome infants hospitalized with confirmed infection during wave. We conducted retrospective all consecutive symptomatic COVID-19 no other co-infections, from January September 2022 one largest infectious diseases hospitals...