- Neonatal and fetal brain pathology
- Neuroscience of respiration and sleep
- Mollusks and Parasites Studies
- Electromagnetic Fields and Biological Effects
- Thermal Regulation in Medicine
- Neurobiology and Insect Physiology Research
- Environmental Toxicology and Ecotoxicology
- Insect and Arachnid Ecology and Behavior
- Magnetic and Electromagnetic Effects
- Anesthesia and Neurotoxicity Research
- Physiological and biochemical adaptations
- Insect and Pesticide Research
- Stress Responses and Cortisol
- Parasite Biology and Host Interactions
- Adipose Tissue and Metabolism
- Human Health and Disease
- Spaceflight effects on biology
- Neonatal Respiratory Health Research
- Hormonal Regulation and Hypertension
- Insect Utilization and Effects
- Viral gastroenteritis research and epidemiology
- High Altitude and Hypoxia
- Birth, Development, and Health
- Nerve injury and regeneration
- bioluminescence and chemiluminescence research
Nicolaus Copernicus University
2015-2024
European Centre for Disease Prevention and Control
2012-2014
Health Protection Surveillance Centre
2014
Health Service Executive
2014
National Institute of Public Health
2012
Jan Kochanowski University
2009
Binary file ES_Abstracts_Final_ECDC.txt matches
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis sativa. It has therapeutic effects in different paradigms of brain injury, acting as neuroprotectant. As oxidative stress primary risk factor for damage after neonatal hypoxia, we tested the effect CBD on status and non-protein-bound iron accumulation immature hypoxia. Moreover, whether cannabidiol affects hypoxia-inducible factor-1 alpha (HIF-1α) which plays key role regulation cellular adaptation to hypoxia...
In May 2013, a European alert was issued regarding hepatitis A virus (HAV) outbreak in Italy. June HAV subgenotype IA with an identical sequence identified Ireland three cases who had not travelled to The investigation consisted of descriptive epidemiology, case-control study, microbiological testing human and food specimens, molecular typing positive specimens traceback. We 21 (14 confirmed primary cases) symptom onset between 31 January 11 October 2013. For the we recruited 42 matched...
Hypoxic-ischaemic brain injury involves increased oxidative stress. In asphyxiated newborns iron deposited in the catalyses formation of reactive oxygen species. Glutathione (GSH) and vitamin E are key factors protecting cells against such agents. Our previous investigation has demonstrated that newborn rats, showing physiological low body temperature as well their hyperthermic counterparts injected with deferoxamine (DF) protected iron-mediated, delayed neurotoxicity perinatal asphyxia....
During summer land snails are repeatedly exposed to low oxygen tension and enhanced production of reactive species due aestivation/arousal cycles. To test the role reduced glutathione (GSH – main endogenous antioxidant) effect season on its function we examined activities glutathione-related enzymes concentration GSH in Helix pomatia (1) during their natural cycle (2) after acclimation different thermal photoperiod conditions autumn. Natural aestivation evoked decreases activity reductase...
Introduction: Low-frequency electromagnetic field (50 Hz) (EMF) can modify crucial neuronal processes. Existing data indicate that exposure to EMF may represent a mild stressor and contribute disturbances of the hypothalamic-pituitary-adrenal (HPA) axis. The important regulatory pathways controlling HPA axis activity include two types corticosteroid receptors: mineralocorticoid receptors (MRs) glucocorticoid receptors. They are particularly abundant in hippocampus, key locus feedback...
Arousal of land snails from torpor is inseparably connected with an increase in oxygen consumption leading to oxidative stress. Therefore, activity antioxidant defence system (antioxidant enzymes and reduced glutathione) degree damage (concentration malondialdehyde as index lipid peroxidation) the snail Helix pomatia L., 1758 were tested check whether torpid are able activate their antioxidative against prior arousal winter torpor. Snails, which collected natural habitats, at beginning,...
Abstract During summer, land snails are exposed to estivation/arousal cycles that imposes oxidative stress, but they exhibit different patterns of antioxidant defence. To test the ability two related species, Helix pomatia and aspersa , modulate their defence mechanism during cycles, we examined activities catalase glutathione‐related enzymes concentrations glutathione thiobarbituric acid reactive substances (TBARS; as products lipid peroxidation). In both estivation evoked changes in...
Transcriptional hypoxia-inducible factor-1α (HIF-1α) plays the fundamental role in adaptive processes response to hypoxia. Specific HIF-1α target genes are involved glycolysis, erythropoiesis and angiogenesis promote survival. In our previous study we have demonstrated that naturally low body temperature of newborn rats protects them against damage due perinatal Therefore, experiments aimed at checking effects during simulated anoxia on subsequent changes expression its specific such as...
Exposure to electromagnetic field (EMF) induces physiological changes in organism that are observed at different levels—from biochemical processes behavior. In this study, we evaluated the effect of EMF exposure (50 Hz, 7 mT) on cockroach's response noxious heat, measured as latency escape from high ambient temperature. We also levels lipid peroxidation and glutathione content markers oxidative balance cockroaches exposed EMF. Our results showed for 24, 72 h days significantly increases...
A prospective survey was conducted in patients admitted to 11 randomly selected general practices and eight hospitals located six provinces of Poland. For each patient meeting the international acute gastrointestinal infection (AGI) case definition criteria, information collected on healthcare resources used. Antibacterial drug consumption assessed using defined daily doses (DDD) extrapolated national level results from a parallel study AGI incidence community. Additionally, logistic...
Capsaicin is known to activate heat receptor TRPV1 and induce changes in thermoregulatory processes of mammals. However, the mechanism by which capsaicin induces responses invertebrates unknown. Insect thermoreceptors belong TRP receptors family, are be activated not only temperature, but also other stimuli. In following study, we evaluated effects different ligands that have been shown (allyl isothiocyanate) or inhibit (camphor) receptors, as well as, (menthol thymol) cold insects....
Abstract Insecticides are dedicated to impair the insect organisms, but also have an impact on other, non-target including humans. In this way, they became important risk factor for disturbance of physiological homeostasis and can be involved in development diseases or deterioration existing conditions. The influence sublethal doses various insecticides vertebrates’ invertebrates’ organisms has been previously observed. paper, we evaluated exposure extremely low dose neurotoxin, bendiocarb...
Background: Extremely low-frequency (50 Hz) electromagnetic field (ELF-EMF) is produced by electric power transmission lines and electronic devices of everyday use.Some phenomena are proposed as "first effects" ELF-EMF: the discrete changes in membrane potential increase calcium channel activity well intracellular concentration Ca 2+ .Interaction scorpion alpha toxin with sodium depends on orientation charges may be perturbed polarization.The induces overexcitability nervous system an...