A5036831540- Mollusks and Parasites Studies
- Environmental Toxicology and Ecotoxicology
- Physiological and biochemical adaptations
- Polish socio-economic development
- Neonatal and fetal brain pathology
- Neuroscience of respiration and sleep
- Parasite Biology and Host Interactions
- Psychedelics and Drug Studies
- Consumer Behavior and Market Dynamics
- Thermal Regulation in Medicine
- Neuroscience and Neuropharmacology Research
- Digital Mental Health Interventions
- Neurobiology and Insect Physiology Research
- Anesthesia and Neurotoxicity Research
- Chemical synthesis and alkaloids
- Pharmacological Effects and Toxicity Studies
- Management and Organizational Practices
- Health, Work, and Social Studies in Poland
- Social Issues in Poland
- Botany and Plant Ecology Studies
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Electromagnetic Fields and Biological Effects
- Globalization, Economics, and Policies
- Eicosanoids and Hypertension Pharmacology
University of Leicester
2024
Nicolaus Copernicus University
2014-2024
University of Aberdeen
2019
Poznan University of Medical Sciences
2011
Polish Academy of Sciences
2010
University of Information Technology and Management in Rzeszow
2009
Jan Kochanowski University
2009
Wyższa Szkoła Przedsiębiorczości i Marketingu w Chrzanowie
2004
Krakow University of Economics
1984-1991
Background: The largest randomized study of psilocybin to date demonstrated the efficacy COMP360 25 mg (Compass Pathways' investigational proprietary pharmaceutical-grade synthesized formulation) in participants with treatment-resistant depression (COMP 001), compared 10 and 1 doses. Here, we report findings from COMP 004, a 52-week observational follow-up patients 001 003, small open-label coadministration continuing antidepressant treatment. Methods: Adverse events (AEs) were collected...
The emergence of an another bluetongue virus serotype BTV-3 has been causing great losses in animal farming Europe since fall 2023. spreads faster than the epidemic BTV-8, which appeared on continent nine years earlier. study describes first case Poland detected European bison (Bison bonasus), just approx. 15 km from German-Polish border. suffered severe and fatal hemorrhagic disease. symptoms included respiratory problems, bloody diarrhea rapidly progressive cachexia. In addition to...
Abstract Prey reconfigure their physiology to avoid costs of prolonged predator pressure. However, these changes might not occur under periodic predation risk, with repeating acute phases. To test the effect risk continuity on in prey physiology, we exposed amphipods: Dikerogammarus villosus and Gammarus jazdzewskii constant cue. After one week, measured: cellular defence systems: total antioxidant status (TAS), heat shock proteins (Hsp70); intracellular damage marker: lipid peroxidation...
Hypoxic-ischaemic brain injury involves increased oxidative stress. In asphyxiated newborns iron deposited in the catalyses formation of reactive oxygen species. Glutathione (GSH) and vitamin E are key factors protecting cells against such agents. Our previous investigation has demonstrated that newborn rats, showing physiological low body temperature as well their hyperthermic counterparts injected with deferoxamine (DF) protected iron-mediated, delayed neurotoxicity perinatal asphyxia....
As acute stress induced by predation risk can generate significant oxidative damage, prey organisms are forced to balance their defence reaction and the cost of activating cellular system. Stress tolerance differs significantly among species; therefore predator pressure indirectly shapes community structure. To test adaptation abilities amphipod crustaceans (Dikerogammarus villosus Gammarus jazdzewskii) we exposed them (35 min.) chronic (1 or 7 days) (the Eurasian perch). We measured...
During summer land snails are repeatedly exposed to low oxygen tension and enhanced production of reactive species due aestivation/arousal cycles. To test the role reduced glutathione (GSH – main endogenous antioxidant) effect season on its function we examined activities glutathione-related enzymes concentration GSH in Helix pomatia (1) during their natural cycle (2) after acclimation different thermal photoperiod conditions autumn. Natural aestivation evoked decreases activity reductase...
Citation Jerzak M, Niemiec T, Nowakowska A, Klochowicz Górski Baranowski W. First successful pregnancy after addition of enoxaparin to sildenafil and etanercept immunotherapy in woman with fifteen failed vitro fertilization (IVF) cycles – case report. Am J Reprod Immunol 2010; 64: 93–96 Problem Does improve IVF outcome? Methods Report a striking 15 failures. Result When was added, the 16th cycle generated healthy male baby. Conclusions Combination therapy that includes heparin may allow...
Arousal of land snails from torpor is inseparably connected with an increase in oxygen consumption leading to oxidative stress. Therefore, activity antioxidant defence system (antioxidant enzymes and reduced glutathione) degree damage (concentration malondialdehyde as index lipid peroxidation) the snail Helix pomatia L., 1758 were tested check whether torpid are able activate their antioxidative against prior arousal winter torpor. Snails, which collected natural habitats, at beginning,...
Abstract During summer, land snails are exposed to estivation/arousal cycles that imposes oxidative stress, but they exhibit different patterns of antioxidant defence. To test the ability two related species, Helix pomatia and aspersa , modulate their defence mechanism during cycles, we examined activities catalase glutathione‐related enzymes concentrations glutathione thiobarbituric acid reactive substances (TBARS; as products lipid peroxidation). In both estivation evoked changes in...
Purpose: Glutathione constitutes the first line of cellular defence mechanism against oxidative stress, and according to published data it is required by a number factors that are involved in fever mechanism. The aim present study was investigate whether or not glutathione deficiency can modulate course induced endotoxin (LPS). Material methods: Intraperitoneal injection LPS from Escherichia coli used provoke Wistar rats. level liver decreased administration phorone (Pho). Deep body...
Transcriptional hypoxia-inducible factor-1α (HIF-1α) plays the fundamental role in adaptive processes response to hypoxia. Specific HIF-1α target genes are involved glycolysis, erythropoiesis and angiogenesis promote survival. In our previous study we have demonstrated that naturally low body temperature of newborn rats protects them against damage due perinatal Therefore, experiments aimed at checking effects during simulated anoxia on subsequent changes expression its specific such as...
Exposure to electromagnetic field (EMF) induces physiological changes in organism that are observed at different levels—from biochemical processes behavior. In this study, we evaluated the effect of EMF exposure (50 Hz, 7 mT) on cockroach's response noxious heat, measured as latency escape from high ambient temperature. We also levels lipid peroxidation and glutathione content markers oxidative balance cockroaches exposed EMF. Our results showed for 24, 72 h days significantly increases...
Some natural alkaloids, e.g. capsaicin and camphor, are known to induce a desensitization state, causing insensitivity pain or noxious temperatures in mammals by acting on TRP receptors. Our research, for the first time, demonstrated that phenomenon of pharmacological blockade heat sensitivity may operate American cockroach, Periplaneta americana (L.). We studied escape reaction time from 50°C cockroaches exposed multiple doses different drugs affecting thermo-TRP. Capsaicin, capsazepine,...
1. Bailey S. E. R. 1981. Circannual and circadian rhythms in the snail Helix aspersa Muller photoperiodic control of annual activity reproduction. J. Comp. Physiol. 142A: 89–94. http://dx.doi.org/10.1007/BF00.... CrossRef Google Scholar