Wojciech Łopuszyński

ORCID: 0000-0002-9875-5449
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Research Areas
  • Veterinary Oncology Research
  • Infectious Diseases and Mycology
  • Virus-based gene therapy research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Microbial infections and disease research
  • Cancer and Skin Lesions
  • Glycosylation and Glycoproteins Research
  • Oral and Maxillofacial Pathology
  • Agriculture, Plant Science, Crop Management
  • Milk Quality and Mastitis in Dairy Cows
  • Hedgehog Signaling Pathway Studies
  • Meat and Animal Product Quality
  • Reproductive Physiology in Livestock
  • Animal Genetics and Reproduction
  • Cancer-related Molecular Pathways
  • Animal health and immunology
  • Effects of Environmental Stressors on Livestock
  • Cancer Diagnosis and Treatment
  • Coccidia and coccidiosis research
  • Neuroendocrine Tumor Research Advances
  • Genital Health and Disease
  • Vector-Borne Animal Diseases
  • Veterinary Equine Medical Research
  • TGF-β signaling in diseases

University of Life Sciences in Lublin
2015-2025

Pathological Society
2016-2017

University of Córdoba
2016

Instytut Środowiska Rolniczego i Leśnego Polskiej Akademii Nauk
2003

In this study, we have determined the prognostic value of presence micrometastases and metastases greater than 2 mm in regional lymph nodes for bitches with mammary carcinomas. The study involved 51 dogs diagnosed a single malignant epithelial tumour 4th or 5th gland. All animals underwent mastectomy; glands were removed together inguinal node. examined immunohistochemically using anti‐cytokeratin antibody, clone AE1/AE3. followed up every 6 months years after surgery to determine...

10.1111/j.1476-5829.2011.00268.x article EN Veterinary and Comparative Oncology 2011-04-21

The degree of differentiation mast cell tumours (MCTs) is the most important feature and reflects morphological characteristics metastatic potential tumour its likely response to treatment prognosis. aim this study was epidemiologically analyse risk MCT development in dogs according breed, age, sex, size anatomical location using Kiupel grading system. analysis involved 492 selected based on a histopathological assessment 2763 canine skin tumours. A logistic regression performed determine...

10.1186/s13028-018-0424-2 article EN cc-by Acta veterinaria Scandinavica 2018-11-03

The emergence of an another bluetongue virus serotype BTV-3 has been causing great losses in animal farming Europe since fall 2023. spreads faster than the epidemic BTV-8, which appeared on continent nine years earlier. study describes first case Poland detected European bison (Bison bonasus), just approx. 15 km from German-Polish border. suffered severe and fatal hemorrhagic disease. symptoms included respiratory problems, bloody diarrhea rapidly progressive cachexia. In addition to...

10.20944/preprints202503.0440.v1 preprint EN 2025-03-06

Since the emergence of serotype BTV-3, another bluetongue virus, in fall 2023, this variant has been causing great losses livestock farming Europe. The virus spreads faster than epidemic BTV-8, which appeared on continent nine years earlier. This study describes first case BTV-3 Poland detected a European bison (Bison bonasus) Poland’s Wolin National Park, approximately 15 km from German–Polish border. animal suffered severe and fatal hemorrhagic disease. symptoms included respiratory...

10.3390/pathogens14040377 article EN cc-by Pathogens 2025-04-12

Abstract The aim of the study was to identify significant relationships between tumour malignancy grade and dogs’ age, breed, sex, size, location mast cell tumours (MCTs). MCTs accounted for 13.27% all diagnosed canine skin tumours. highest incidence recorded among Boxers, Labrador Retrievers, American Staffordshire Terriers, Golden Retrievers. Statistical analysis revealed significantly higher probability occurrence I in French Bulldog head, neck, torso, limb regions, grade-II Boxer,...

10.1515/pjvs-2017-0055 article EN cc-by-nc-nd Polish Journal of Veterinary Sciences 2017-09-26

Abstract In this study, we have determined serum neopterin levels in female dogs with primary malignant mammary tumours. The study involved 50 which had a tumours removed surgically (32 animals carcinoma, 12 sarcoma and 6 carcinosarcoma) 10 clinically healthy dogs. Serum were using commercial ELISA kit. mean lower the tumour groups than but differences statistically significant only carcinoma groups. decrease of may suggest their decreased cellular immunity. Moreover, it might indicate that...

10.1111/j.1476-5829.2012.00347.x article EN Veterinary and Comparative Oncology 2012-08-10

Breed predisposition to cutaneous mast cell tumours (MCT) in a population of dogs Poland affected by various skin was assessed, and the distribution MCT characteristics such as histological grading, sex, age, location, predisposed breeds evaluated. The retrospective epidemiological study included 550 MCTs with reference group 2,557 diagnosed other tumours. A univariable logistic regression analysis performed determine odds ratios (ORs) 95% confidence intervals. risk high-grade highest for...

10.2478/jvetres-2019-0002 article EN cc-by-nc-nd Journal of Veterinary Research 2019-02-05

Summary The aim of the present study was to describe some oxidative stress parameters in bitches suffering from spontaneusly occurring mammary gland tumours. experiment involved 28 which had tumours removed surgically (15 with malignant tumour and 13 benign tumour) as well 10 clinically healthy bitches. activities glutathione peroxidase (GSH‐Px) superoxide dismutase (SOD) were determined haemolysates erythrocytes derived animals. concentrations thiobarbituric acid reactive substances...

10.1111/j.1439-0442.2004.00647.x article EN Journal of Veterinary Medicine Series A 2004-09-01

Abstract The study was carried out in a herd of 280 dairy cows the North-Eastern part Poland summer 2011. During period 5-6 months before study, mastitis cases resistant to routine antibiotic therapy were observed this herd. Bacteriological examination milk samples collected from 70 with clinical or subclinical forms performed. Diagnosis made on basis anamnesis, udder, macroscopic evaluation secretion, California test (CMT), and results bacteriological milk. Protothecal detected 34 (12.6%...

10.2478/bvip-2013-0058 article EN Bulletin of the Veterinary Institute in Pulawy 2013-09-01

In the perianal region of carnivores, skin consists modified sebaceous glands called glands. Tumors originating from are third most frequent type neoplasm in male dogs after neoplastic diseases testes and skin. Ki-67 is a nuclear non-histone protein considered proliferation marker normal proliferating cells. Previous investigations revealed that expression may be used as prognostic factor for breast cancer humans. Thus, aim this study was to estimate diagnostic value evaluation suffering...

10.3409/fb62_3.235 article EN Folia Biologica 2014-07-31

The presented paper provides a reclassification of Eimeria pogonae from Pogona vitticeps into the correct genus Choleoeimeria. A description exogenous and endogenous stages biliary coccidium is given. Sporulation oocysts was endogenous. mature contained four sporocysts each with two sporozoites. Oocysts were ellipsoidal in shape, average length/width ratio 1.7 measured 28.4 (SD1.5) × 16.8 (SD 1.5). micropyle, residuum, polar granules absent sporulated oocysts. Ovoidal sporosysts without...

10.1007/s00436-015-4787-2 article EN cc-by Parasitology Research 2015-10-14

Research has revealed the presence of somatic mutations in mitochondrial DNA (mtDNA) certain types tumours. As this not been studied for canine mast cell tumours, aim study was to identify hypervariable region mtDNA tumours dogs and determine their association with process neoplastic transformation.Samples from 17 histopathologically confirmed were analysed. The samples consisted tumour tissues (n = 17), normal blood 17). Amplicons displacement loop (D-loop) sequenced obtained nucleotide...

10.1186/s13028-016-0210-y article EN cc-by Acta veterinaria Scandinavica 2015-12-01

The aim of the study was to analyze endoparasitic fauna in roe deer a selected area south-western Poland using coproscopic studies and postmortem internal organs (lungs, livers digestive tracts). Microscopic methods included flotation McMaster method. In May June 2015, 53 culled male were examined. Parasites found 96.2% (n=51, SD=19.2) studied animals, but invasion intensity diversified. From 1 7 different taxa (families or genera) parasites each animal. Oocysts Eimeria (3 species (E....

10.21521/mw.5799 article EN Medycyna Weterynaryjna 2017-01-01

Abstract Background The authors report a case of keratinized squamous cell carcinoma (SCC) in 14-year-old dog with extensive cranial bone invasion. To our knowledge, this is the first description such SCC aggressive generalized osteolysis described dog. Case presentation was referred for radiological examination suspicion head trauma clinical signs deformation, exophthalmos and nasal discharge. skull radiographs showed large osteolytic defect frontal parietal region external sagittal crest....

10.1186/s12917-021-02843-8 article EN cc-by BMC Veterinary Research 2021-04-06

Based upon promising preclinical studies, a clinical trial was performed in which encapsulated cells overexpressing cytochrome P450 enzyme isoform 2B1 were implanted around malignant mammary tumours arising spontaneously dogs. The dogs then given cyclophosphamide, one of the standard chemotherapeutic agents used for treatment tumours. assessed number parameters as well reduction tumour size. tolerated with no evidence adverse reactions or side effects being associated administration cells....

10.1371/journal.pone.0102061 article EN cc-by PLoS ONE 2014-07-16

The aim of the study was to compile data on frequency and distribution canine skin tumours determine risk these being malignant as opposed benign. This determination proceeded from tumour histogenesis gave consideration dog's breed, sex, age anatomical location tumours.This retrospective five-year epidemiological included 3,139 collected in Poland. A univariable logistic regression analysis performed odds ratios (ORs) with 95% confidence intervals (CIs).Microscopic showed a significant...

10.2478/jvetres-2023-0048 article EN cc-by-nc-nd Journal of Veterinary Research 2023-08-31

Abstract The subject of the study were dogs divided into two groups according to body weight: up 10 kg and from 30 kg. aim was determine dynamics post-mortem decrease in rectal kidney temperature. temperature measured on both sites at same time using a thermometer connected computer, under constant environmental conditions necropsy room. In these animals, higher kidneys persisted for duration study. Comparative analysis between mean differences small large showed greatest amplitude group...

10.1515/acve-2016-0006 article EN cc-by Acta veterinaria 2016-03-01

Twenty-eight canine mammary tubulopapillary carcinomas and 14 simple adenomas were studied by immunohistochemistry for the expressions of tumor-associated carbohydrate antigens. Sialyl Le(a) was detected in 71.42% malignant 92.84% benign tumors. Staining with anti-T anti-Tn monoclonal antibodies revealed that 85.70% expressed T Tn In contrast, 50% did not express antigen, 42.85% them only weakly stained this structure. case majority (57.14%) samples stained, no binding observed 35.71%...

10.1354/vp.46-2-222 article EN Veterinary Pathology 2009-03-01

A widespread availability of firearms makes animals the victims both intentional and accidental shootings by man. In Poland, statistical surveys on gunshot cases in are not carried out. The present authors attempt to assess frequency character injuries basis their observations from 2000-2009, taking into account changes law regulating firearms. material involved 171 study protocols patients whose radiological evaluation revealed presence bullets. analysis covered different species animals,...

10.21521/mw.5531 article EN Medycyna Weterynaryjna 2016-01-01

The aim of this study was to measure serum neopterin and C-reactive protein (CRP) concentrations in female dogs with mammary tumours evaluate the association between values these indicators some clinical characteristics tumour.Fifty three were used for study, including 43 gland (10 benign 33 malignant) 10 healthy controls.The CRP determined using ELISA technique commercial kits.The mean concentration lower than dogs, but significant difference not found.Similarly, there no differences based...

10.24425/124307 article EN Polish Journal of Veterinary Sciences 2018-08-22

Perianal gland tumors are modified sebaceous glands present in the skin of perianal region dog. Hormonal stimulation may induce hyperplasia or their neoplastic progression. The presence androgen (AR) and estrogen (ER) receptors have been demonstrated both normal as well tumors. aim study was an immunohistochemical assessment expression dogs applicatory marker for antihormonal treatment. Biopsy samples masses were collected from 41 male dogs. A histopathological examination revealed 24...

10.3390/ani11030875 article EN cc-by Animals 2021-03-19
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