- Pelvic floor disorders treatments
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Reproductive System and Pregnancy
- Advancements in Materials Engineering
- Endometrial and Cervical Cancer Treatments
- Structural Engineering and Materials Analysis
- Urinary Bladder and Prostate Research
- Anorectal Disease Treatments and Outcomes
- Gynecological conditions and treatments
- Mechanical Engineering Research and Applications
- Mechanical and Thermal Properties Analysis
- Urinary Tract Infections Management
- Estrogen and related hormone effects
- Cancer-related molecular mechanisms research
- Material Properties and Failure Mechanisms
- Epigenetics and DNA Methylation
- Geotechnical Engineering and Underground Structures
- Economic and Fiscal Studies
- Tribology and Wear Analysis
- Structural Integrity and Reliability Analysis
- Engine and Fuel Emissions
- Pelvic and Acetabular Injuries
- Management Systems and Quality Improvement
Wojskowy Instytut Medycyny Lotniczej
2009-2023
Jagiellonian University
2021
Wojskowy Instytut Medyczny
2010-2021
National Academy of Medicine
2012-2020
Medical University of Warsaw
2019
Częstochowa University of Technology
2003-2017
Lublin Oncology Center
2016-2017
Military Institute
2004-2015
Gynecologic Oncology Group
2014
Military Communication Institute
2008-2010
In patients with Ovarian Cancer (OvCa) exosomes released by tumor cells are present in the plasma and could be involved progression. This study examines association between exosome presence/protein content of OvCa disease outcome, response to standard therapy and/or tumorresistance therapies studied at diagnosis also serially during after therapy.Exosomes were purified from patients' (n=22), benign tumors (n=10) or healthy controls (NC) using ultracentrifugation. Exosomes visualized scanning...
Is endometriosis associated with changes in CD4+ CD25+ FOXP3+ regulatory T cells (Treg cells)? Endometriosis is disturbed compartmentalization of CD25high Treg cells. an abrogated immune response and displays some features autoimmune disorder. play a part the development reactions; however, their role pathogenesis still poorly recognized. Case–control study comparing 17 women laparoscopically histopathologically confirmed ovarian 15 control without visible foci, pelvic inflammation or...
The prevalence of stress urinary incontinence rises and affects up to 30% women after 50 years age. Midurethral slings are currently the mainstay surgical anti-incontinence therapy. Some patients experience recurrent SUI (RSUI) which is defined as a failure surgery period time or persistence procedure aimed at correcting it. urethral bulking agent application decreases invasiveness treatment meets requirements. objective this study was assess safety clinical efficacy Urolastic injection. One...
Citation Jerzak M, Niemiec T, Nowakowska A, Klochowicz Górski Baranowski W. First successful pregnancy after addition of enoxaparin to sildenafil and etanercept immunotherapy in woman with fifteen failed vitro fertilization (IVF) cycles – case report. Am J Reprod Immunol 2010; 64: 93–96 Problem Does improve IVF outcome? Methods Report a striking 15 failures. Result When was added, the 16th cycle generated healthy male baby. Conclusions Combination therapy that includes heparin may allow...
The aim of this study was to evaluate association expression survivin and p53 with the effects neoadjuvant chemotherapy (NAC) in patients advanced ovarian cancer (AOC).We retrospectively evaluated 60 consecutive AOC (International Federation Gynecology Obstetrics stage IIIC-IV) treated NAC. assessed immunohistochemically. median total score equals 2 adopted dichotomize group. positive negative used group.The tumor tissue taken before after NAC a significant difference percentage stained...
As in the case of cardiovascular and metabolic diseases, prevalence pelvic organ prolapse (POP) has been rising with increasing proportion elderly women population. The purpose present cross-sectional study was to evaluate components syndrome (MS) urogynecological patients a variable POP severity.The MS risk factors (elevated waist circumference, elevated triglycerides, decreased high-density lipoprotein cholesterol, blood pressure, hyperglycemia) were assessed 100 who referred our center...
A population-based organised cervical cancer screening programme (OCCSP) was introduced in Poland 2006. In this study we have aimed to analyse whether selected parameters related invasive (ICC) of patients diagnosed two distant gynaecological oncology centres changed after the first round run between 2006–2008. We a retrospective cross-sectional analysis 189 women with ICC 2002–2005 (directly before introduction programme) and 165 2009–2012 (just compared their age at diagnosis, histology,...
Ovarian cancer has one of the highest death/incidence rates and is commonly diagnosed at an advanced stage. In recent WHO classification, new histotypes were classified which respond differently to chemotherapy. The e-standardized synoptic pathology reports offer clinicians essential reliable information. aim our project was develop e-template for standardized reporting ovarian carcinoma [based on checklist College American Pathologists (CAP) WHO/FIGO classification] introduce a uniform...
The aim of this study was to selectively profile the activation status mammalian target rapamycin (mTOR)-associated oncogenes and tumor suppressor genes (TSGs) in ovarian cancer specimens, healthy ovaries benign tumors, including endometrial cysts. We used a novel type microfluidic gene array examine expression 15 human suppressors specimens 53 patients, cysts 29 women (endometrial simple) 11 individuals whom material obtained during total hysterectomies performed because fibroid changes....
Transgenic mice provide a unique tool for studying the tissue specificity and mutagenic potential of chemicals. Because 3-methylcholanthrene (3MC) was found in bacteria, clastogenic bone marrow, induces DNA adducts animals, we were interested to determinine whether this xenobiotic provokes (1) cell proliferation, (2) transcriptional activity changes, (3) adducts, (4) hepatic mutations transgenic Big Blue® carrying λLIZ phage shuttle vector. Blue C57/Bl male treated with single...